Featured Publications
A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging
Damisah EC, Hill RA, Tong L, Murray KN, Grutzendler J. A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging. Nature Neuroscience 2017, 20: 1023-1032. PMID: 28504673, PMCID: PMC5550770, DOI: 10.1038/nn.4564.Peer-Reviewed Original ResearchIn vivo imaging of oligodendrocytes with sulforhodamine 101
Hill RA, Grutzendler J. In vivo imaging of oligodendrocytes with sulforhodamine 101. Nature Methods 2014, 11: 1081-1082. PMID: 25357236, PMCID: PMC4539948, DOI: 10.1038/nmeth.3140.Peer-Reviewed Original Research
2015
Absolute two-photon excitation spectra of red and far-red fluorescent probes.
Velasco MG, Allgeyer ES, Yuan P, Grutzendler J, Bewersdorf J. Absolute two-photon excitation spectra of red and far-red fluorescent probes. Optics Letters 2015, 40: 4915-8. PMID: 26512482, DOI: 10.1364/ol.40.004915.Peer-Reviewed Original Research
2011
Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition
Condello C, Schain A, Grutzendler J. Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition. Scientific Reports 2011, 1: 19. PMID: 22355538, PMCID: PMC3216507, DOI: 10.1038/srep00019.Peer-Reviewed Original ResearchConceptsPlaque burdenAmyloid depositionAlzheimer's diseaseAD mouse modelPlaque enlargementClinicopathological studyNeuritic dystrophyPathogenic rolePostmortem studiesAmyloid plaquesNew plaquesConsequent neurotoxicityMouse modelOld plaquesQuantitative confocal imagingCognitive statusPlaquesPlaque expansionOld animalsAmyloid-binding dyesNeurotoxicityDiseasePoor correlationBurdenCritical determinant
2009
Ballistic delivery of dyes for structural and functional studies of the nervous system.
Gan WB, Grutzendler J, Wong RO, Lichtman JW. Ballistic delivery of dyes for structural and functional studies of the nervous system. Cold Spring Harbor Protocols 2009, 2009: pdb.prot5202. PMID: 20147144, PMCID: PMC2916724, DOI: 10.1101/pdb.prot5202.Peer-Reviewed Original Research
2003
Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes
Grutzendler J, Tsai J, Gan WB. Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes. Methods 2003, 30: 79-85. PMID: 12695105, DOI: 10.1016/s1046-2023(03)00009-4.Peer-Reviewed Original Research