2007
Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid Deposits in Alzheimer's Disease
GRUTZENDLER J, HELMIN K, TSAI J, GAN W. Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid Deposits in Alzheimer's Disease. Annals Of The New York Academy Of Sciences 2007, 1097: 30-39. PMID: 17413007, DOI: 10.1196/annals.1379.003.Peer-Reviewed Original ResearchConceptsAmyloid depositsAlzheimer's diseasePSAPP miceFibrillar amyloid depositsAmyloid depositionDendritic abnormalitiesHuman AD tissueFibrillar amyloid depositionHuman AD brainsTransgenic mouse modelHuman postmortem brainDystrophic neuritesSpine lossAD brainAD tissueAmyloid plaquesCommon abnormalityMouse modelPostmortem brainsDendritic spinesNeuronal circuitsVaricosity formationSynaptic structureDiseaseDendritic branches
2000
Multicolor “DiOlistic” Labeling of the Nervous System Using Lipophilic Dye Combinations
Gan W, Grutzendler J, Wong W, Wong R, Lichtman J. Multicolor “DiOlistic” Labeling of the Nervous System Using Lipophilic Dye Combinations. Neuron 2000, 27: 219-225. PMID: 10985343, DOI: 10.1016/s0896-6273(00)00031-3.Peer-Reviewed Original ResearchConceptsNervous systemGolgi-like labelingNormal synaptic responsesComplex neuronal networksDendritic remodelingSynaptic responsesNeuronal preparationsNeuronal connectivityNeuronal circuitsIndividual neuronsNeuronsDye-coated particlesGene gunNeuronal networksStructural plasticityLipophilic dyeCellsGliaDiOlisticsLabeling