2020
Primary sclerosing cholangitis associated colitis: Characterization of clinical, histologic features, and their associations with liver transplantation
Aranake-Chrisinger J, Dassopoulos T, Yan Y, Nalbantoglu I. Primary sclerosing cholangitis associated colitis: Characterization of clinical, histologic features, and their associations with liver transplantation. World Journal Of Gastroenterology 2020, 26: 4126-4139. PMID: 32821074, PMCID: PMC7403798, DOI: 10.3748/wjg.v26.i28.4126.Peer-Reviewed Original ResearchMeSH KeywordsCholangitis, SclerosingColitis, UlcerativeCrohn DiseaseHumansInflammatory Bowel DiseasesLiver TransplantationConceptsInflammatory bowel diseaseOrthotopic liver transplantationPSC-IBD patientsUlcerative colitisCrohn's diseasePSC-UCLiver transplantationHistologic featuresLeft colonPSC-UC patientsPrimary sclerosing cholangitisRight-sided diseaseWarrants clinical attentionDifferent disease phenotypesIBD durationIBD patientsPSC patientsSclerosing cholangitisUC patientsActive inflammationRectal involvementBowel diseaseClinical featuresPSC diagnosisLess steroids
2014
Differential expression of miR-31 between inflammatory bowel disease and microscopic colitis.
Zhang C, Zhao Z, Osman H, Watson R, Nalbantoglu I, Lin J. Differential expression of miR-31 between inflammatory bowel disease and microscopic colitis. MicroRNA 2014, 3: 155-9. PMID: 25665881, DOI: 10.2174/2211536604666150209115444.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersColitis, MicroscopicColitis, UlcerativeCrohn DiseaseFemaleHumansMaleMicroRNAsMiddle AgedConceptsIdiopathic inflammatory bowel diseaseMicroscopic colitisInflammatory bowel diseaseLymphocytic colitisCollagenous colitisMiR-31 expressionBowel diseaseMiR-31Colonic tissueSeparate disease processesMC episodesUlcerative colitisCrohn's diseaseExpression patternsColitisIntermittent episodesNormal controlsDisease processUseful biomarkerDifferential expressionPatientsColon tissuesDistinct entityDiseaseQRT-PCR
2011
Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis
Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, Aitken JD, Su Y, Koren O, Walters WA, Knight R, Ley RE, Vijay-Kumar M, Gewirtz AT. Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis. Gut 2011, 61: 373. PMID: 21646247, DOI: 10.1136/gut.2011.240556.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalCecumColitis, UlcerativeDisease Models, AnimalDisease SusceptibilityGene Expression ProfilingInterleukin-1betaMaleMetagenomeMiceMice, KnockoutMyeloid Differentiation Factor 88Receptors, Interleukin-10Reverse Transcriptase Polymerase Chain ReactionSignal TransductionToll-Like Receptor 5ConceptsToll-like receptor 4T5KO miceGut microbiotaColitis modelIL-1βAbsence of TLR4Toll-like receptor 5 deficient (T5KO) miceAnti-inflammatory cytokine interleukin-10Endogenous anti-inflammatory pathwayToll-like receptor 5Loss of TLR5Anti-inflammatory pathwayIL-10 receptorCytokine interleukin-10Double knockoutIL-10 signalingIL-1 receptorProinflammatory gene expressionWild-type littermatesColitogenic microbiotaSpontaneous colitisUniform colitisSevere colitisImmune dysregulationIntestinal inflammation