2022
An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis
Pi H, Weiss A, Laut C, Grunenwald C, Lin H, Yi X, Stauff D, Skaar E. An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis. Nature Communications 2022, 13: 1491. PMID: 35314695, PMCID: PMC8938561, DOI: 10.1038/s41467-022-29209-4.Peer-Reviewed Original ResearchConceptsHuman pathogen Bacillus anthracisRNA-binding proteinPost-transcriptional modulatorsPathogen Bacillus anthracisDetectable nuclease activityTwo-component systemBacillus anthracisGenetic competenceRNA turnoverDNA repairMRNA stabilityCellular metabolismNuclease activityEnvelope damageRNAProteinMultiple processesAnthracisHITRSporulationGenesMRNAExpressionMetabolismTurnoverA Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress
Wendel B, Pi H, Krüger L, Herzberg C, Stülke J, Helmann J. A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress. MBio 2022, 13: e00092-22. PMID: 35164567, PMCID: PMC8844918, DOI: 10.1128/mbio.00092-22.Peer-Reviewed Original ResearchConceptsResumption of growthOsmotic stressCompatible solutesCellular responsesBacillus subtilisDomains of lifeHigh salt stressCommon cellular responseEssential second messengerSpecific efflux pumpsSalt stressProtein translationOsmotic upshiftHyperosmotic stressSecond messengerHigh osmolarityReimportLiving cellsTransient growth inhibitionEfflux pumpsModel system
2011
Sortase independent and dependent systems for acquisition of haem and haemoglobin in Listeria monocytogenes
Xiao Q, Jiang X, Moore K, Shao Y, Pi H, Dubail I, Charbit A, Newton S, Klebba P. Sortase independent and dependent systems for acquisition of haem and haemoglobin in Listeria monocytogenes. Molecular Microbiology 2011, 80: 1581-1597. PMID: 21545655, PMCID: PMC3115469, DOI: 10.1111/j.1365-2958.2011.07667.x.Peer-Reviewed Original Research
2002
A novel human SCAN/(Cys)2(His)2 zinc-finger transcription factor ZNF323 in early human embryonic development
Pi H, Li Y, Zhu C, Zhou L, Luo K, Yuan W, Yi Z, Wang Y, Wu X, Liu M. A novel human SCAN/(Cys)2(His)2 zinc-finger transcription factor ZNF323 in early human embryonic development. Biochemical And Biophysical Research Communications 2002, 296: 206-213. PMID: 12147252, DOI: 10.1016/s0006-291x(02)00772-6.Peer-Reviewed Original ResearchIdentification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development
Zhou L, Zhu C, Luo K, Li Y, Pi H, Yuan W, Wang Y, Huang C, Liu M, Wu X. Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development. Biochemical And Biophysical Research Communications 2002, 295: 862-868. PMID: 12127974, DOI: 10.1016/s0006-291x(02)00759-3.Peer-Reviewed Original ResearchConceptsZinc finger geneAmino acid proteinFinger geneKRAB domainTranscription factorsCDNA sequenceAcid proteinC2H2 zinc finger motifsN-terminal KRAB domainNovel zinc finger geneDevelopment-specific expression patternsN-terminal signal peptideHuman heart cDNA libraryZinc finger motifsHeart cDNA librarySingle largest classNorthern blot analysisC2H2 motifFinger motifRegulatory genesHuman genomeSignal peptideEmbryonic developmentCDNA libraryCardiac development