2020
Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing
Gorecka J, Gao X, Fereydooni A, Dash BC, Luo J, Lee SR, Taniguchi R, Hsia HC, Qyang Y, Dardik A. Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing. Regenerative Medicine 2020, 15: 1277-1293. PMID: 32228292, PMCID: PMC7304438, DOI: 10.2217/rme-2019-0086.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiabetes Mellitus, ExperimentalDiabetic FootHumansInduced Pluripotent Stem CellsMaleMesenchymal Stem CellsMiceMice, NudeMyocytes, Smooth MuscleNeovascularization, PhysiologicWound HealingConceptsSmooth muscle cellsMuscle cellsDiabetic wound healingWound healingPro-angiogenic cytokinesMurine AdiposeStem cellsType macrophagesCollagen scaffoldsCultured mediumM2-type macrophagesCellsNumber of totalNew candidatesAngiogenesisNude miceDiabetic woundsPromising new candidateScaffoldsHealingCytokinesExpressionSecreteWoundsAdipose
2015
SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds
Olekson MA, Faulknor R, Bandekar A, Sempkowski M, Hsia HC, Berthiaume F. SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds. Wound Repair And Regeneration 2015, 23: 711-723. PMID: 26110250, DOI: 10.1111/wrr.12334.Peer-Reviewed Original ResearchMeSH KeywordsAcellular DermisAnimalsCell ProliferationChemokine CXCL12Diabetes Mellitus, ExperimentalHumansLiposomesMiceSkinTissue EngineeringTissue ScaffoldsWound HealingWounds and InjuriesConceptsStromal cell-derived factor-1Acellular dermisCell-derived factor-1Cell proliferationRestoration of skinChronic skin woundsImproved wound closurePersistent cell proliferationCommon complicationGranulation tissue thicknessIschemic tissueProper revascularizationDay 28Day 21Diabetic woundsSuch woundsWound closureSkin woundsDermisFactor 1Tissue thicknessWoundsProliferation