1999
Stimulation of Sodium Chloride Absorption from Secreting Rat Colon by Short-Chain Fatty Acids
Krishnan S, Ramakrishna BS, Binder H. Stimulation of Sodium Chloride Absorption from Secreting Rat Colon by Short-Chain Fatty Acids. Digestive Diseases And Sciences 1999, 44: 1924-1930. PMID: 10505736, DOI: 10.1023/a:1018871412748.Peer-Reviewed Original ResearchConceptsShort-chain fatty acidsNa absorptionNaCl absorptionControl normal mucosaNet Cl secretionRat distal colonSodium chloride absorptionPresence of SCFAEffect of butyrateElectroneutral NaCl absorptionVoltage-clamp conditionsFatty acidsDistal colonNormal mucosaRat colonAbsorptive pathwaysCl(-) secretionChloride absorptionColonCAMP elevationSCFAMucosaSecretagoguesAdenosine monophosphateSecretionDifferential regulation of NHE isoforms by sodium depletion in proximal and distal segments of rat colon
Ikuma M, Kashgarian M, Binder H, Rajendran V. Differential regulation of NHE isoforms by sodium depletion in proximal and distal segments of rat colon. American Journal Of Physiology 1999, 276: g539-g549. PMID: 9950829, DOI: 10.1152/ajpgi.1999.276.2.g539.Peer-Reviewed Original ResearchConceptsDietary sodium depletionSodium depletionDistal colonRat colonProtein expressionMRNA abundanceBlot analysisDose-dependent inhibitorApical membrane vesiclesElectroneutral NaCl absorptionWestern blot analysisDifferential regulationNormal ratsProximal colonHOE 694Multiple diverse effectsColonDistal segmentsNaCl absorptionNHE isoformsExchange activityExchanger isoformsNorthern blot analysisDifferential effectsPretranslational level
1983
Role of calcium in the regulation of colonic secretion in the rat
Zimmerman T, Dobbins J, Binder H. Role of calcium in the regulation of colonic secretion in the rat. American Journal Of Physiology 1983, 244: g552-g560. PMID: 6133455, DOI: 10.1152/ajpgi.1983.244.5.g552.Peer-Reviewed Original ResearchConceptsSerosal calciumRole of calciumExtracellular calciumElectrolyte transportNeutral sodium chloride absorptionEffect of bethanecholEffect of theophyllineMuscarinic cholinergic agonistNet sodium absorptionSodium chloride absorptionNet chloride absorptionCalcium-free mediumNeutral NaCl absorptionColonic secretionCholinergic agonistsIntracellular calciumBethanecholNet sodiumRat colonChloride secretionJNanetSodium absorptionChloride absorptionJClnetNaCl absorption