1987
Inability to predict diagnosis in febrile intravenous drug abusers.
Marantz P, Linzer M, Feiner C, Feinstein S, Kozin A, Friedland G. Inability to predict diagnosis in febrile intravenous drug abusers. Annals Of Internal Medicine 1987, 106: 823-8. PMID: 3579068, DOI: 10.7326/0003-4819-106-6-823.Peer-Reviewed Original ResearchConceptsIntravenous drug abusersFinal diagnosisEmergency roomTrivial illnessDrug abusersDistribution of diseaseInfective endocarditisConsecutive admissionsPhysicians' predictionsClinical dataDiagnostic predictionClinical informationPredictive valuePatientsDiagnosisIllnessLaboratory dataEndocarditisAbusersHospitalizationPneumoniaAdmissionFeverDiseaseA Prospective Longitudinal Study of Neuropsychological and Psychosocial Factors in Asymptomatic Individuals at Risk for Htlv-III/Lav Infection in a Methadone Program: Preliminary Findings
Silberstein C, McKegney F, O'dowd M, Selwyn P, Schoenbaum E, Drucker E, Feiner C, Cox C, Friedland G. A Prospective Longitudinal Study of Neuropsychological and Psychosocial Factors in Asymptomatic Individuals at Risk for Htlv-III/Lav Infection in a Methadone Program: Preliminary Findings. International Journal Of Neuroscience 1987, 32: 669-676. PMID: 3596916, DOI: 10.3109/00207458709043321.Peer-Reviewed Original ResearchConceptsProspective longitudinal studyWAIS similaritiesAssociative learning testHTLV-III/LAV infectionDigit Span ForwardLongitudinal studyImpaired neuropsychological functionLearning TestNeuropsychological functionPsychosocial measuresTest performanceFinger tappingPsychosocial factorsPsychological stressCognitive impairmentPreliminary findingsHTLV-III/LAVIntravenous drug abusersHigh-risk populationAbsence of AIDSDrug useDrug abusersAsymptomatic individualsMethadone programsUnivariate analysis
1986
Mycobacterium tuberculosis Bacteremia in the Acquired Immunodeficiency Syndrome
Saltzman B, Motyl M, Friedland G, McKitrick J, Klein R. Mycobacterium tuberculosis Bacteremia in the Acquired Immunodeficiency Syndrome. JAMA 1986, 256: 390-391. PMID: 3088290, DOI: 10.1001/jama.1986.03380030092036.Peer-Reviewed Original ResearchConceptsAcquired Immunodeficiency SyndromeImmunodeficiency syndromeCellular immunityM tuberculosisMycobacterium avium-intracellulare infectionDisease Control case definitionMycobacterium tuberculosis bacteremiaIntravenous drug abusersUnusual malignant neoplasmFive-year historyIntravenous heroinOpportunistic infectionsDisseminated infectionMalignant neoplasmsCase definitionBacteremiaCocaine abuseDrug abusersBacterial infectionsInfectionMycobacterium tuberculosisWeight lossTuberculosisPatientsSyndrome
1985
Intravenous Drug Abusers and the Acquired Immunodeficiency Syndrome (AIDS): Demographic, Drug Use, and Needle-Sharing Patterns
Friedland G, Harris C, Butkus-Small C, Shine D, Moll B, Darrow W, Klein R. Intravenous Drug Abusers and the Acquired Immunodeficiency Syndrome (AIDS): Demographic, Drug Use, and Needle-Sharing Patterns. JAMA Internal Medicine 1985, 145: 1413-1417. DOI: 10.1001/archinte.1985.00360080085012.Peer-Reviewed Original ResearchAcquired Immunodeficiency SyndromeDrug abuser patientsIntravenous drug abusersDrug abusersImmunodeficiency syndromeNeedle sharingHomosexual menSpread of AIDSPutative AIDS agentPercent of patientsBlood-borne routeDrug use patternsDrug use practicesARC patientsSexual habitsDrug usePatientsShooting galleriesAIDS agentsAIDS transmissionMale homosexualsDemographic characteristicsAbusersSyndromeHigh rateIntravenous drug abusers and the acquired immunodeficiency syndrome (AIDS). Demographic, drug use, and needle-sharing patterns.
Friedland G, Harris C, Butkus-Small C, Shine D, Moll B, Darrow W, Klein R. Intravenous drug abusers and the acquired immunodeficiency syndrome (AIDS). Demographic, drug use, and needle-sharing patterns. JAMA Internal Medicine 1985, 145: 1413-7. PMID: 3875327, DOI: 10.1001/archinte.145.8.1413.Peer-Reviewed Original ResearchConceptsDrug abuser patientsIntravenous drug abusersDrug abusersImmunodeficiency syndromeNeedle sharingHomosexual menPutative AIDS agentPercent of patientsEvidence of AIDSBlood-borne routeDrug use patternsDrug use practicesARC patientsSexual habitsDrug usePatientsShooting galleriesSpread of AIDSAIDS agentsAIDSAIDS transmissionMale homosexualsDemographic characteristicsAbusersSyndrome
1983
Immunodeficiency in Female Sexual Partners of Men with the Acquired Immunodeficiency Syndrome
Harris C, Small C, Klein R, Friedland G, Moll B, Emeson E, Spigland I, Steigbigel N. Immunodeficiency in Female Sexual Partners of Men with the Acquired Immunodeficiency Syndrome. New England Journal Of Medicine 1983, 308: 1181-1184. PMID: 6221192, DOI: 10.1056/nejm198305193082001.Peer-Reviewed Original ResearchConceptsFemale sexual partnersMale patientsImmunodeficiency syndromeSexual partnersProdrome of AIDSSuppressor T cellsAcquired Immunodeficiency SyndromeImmunologic abnormalitiesProdromal illnessBiologic agentsT cellsDrug abusersHealthy adultsSyndromeCurrent outbreakDecreased ratioWomenPatientsHeterosexual menIllnessAbnormalitiesAIDSMenLymphadenopathyLymphopeniaCommunity-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men
Small C, Klein R, Friedland G, Moll B, Emeson E, Spigland I. Community-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men. The American Journal Of Medicine 1983, 74: 433-441. PMID: 6219579, DOI: 10.1016/0002-9343(83)90970-1.Peer-Reviewed Original ResearchConceptsOpportunistic infectionsSevere opportunistic infectionsHomosexual menDrug abusersOral thrushCellular immunityT helper/inducer cellsT suppressor/cytotoxic cellsHelper/inducer cellsSuppressor/cytotoxic cellsHealthy young patientsSyndrome of immunodeficiencyPneumocystis carinii pneumoniaMycobacterium intracellulare infectionDefective cellular immunityWhite homosexual menCutaneous anergyCandida esophagitisYounger patientsNonspecific findingsClinical presentationCarinii pneumoniaCytotoxic cellsInducer cellsIntracellulare infection
1982
Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections
Moll B, Emeson E, Small C, Friedland G, Klein R, Spigland I. Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections. Clinical Immunology 1982, 25: 417-423. PMID: 6218947, DOI: 10.1016/0090-1229(82)90206-9.Peer-Reviewed Original ResearchConceptsT lymphocyte subsetsOpportunistic infectionsOnly opportunistic infectionPercentage of T8Pneumocystis carinii pneumoniaPercentage of T4Ratio of inducerCutaneous anergyCarinii pneumoniaImmune statusPeripheral bloodOral candidiasisProliferative responsePatientsDrug abusersDrug abuseMarked reductionInfectionP. cariniiLymphocytesFurther evidencePneumoniaAnergyHistoplasmosisCandidiasis