2010
Bioanalytical inaccuracy: a threat to the integrity and efficiency of research
Young S, Anderson G. Bioanalytical inaccuracy: a threat to the integrity and efficiency of research. Journal Of Psychiatry And Neuroscience 2010, 35: 3-6. PMID: 20040241, PMCID: PMC2799499, DOI: 10.1503/jpn.090171.Peer-Reviewed Original Research
2004
Time course of the effects of the serotonin-selective reuptake inhibitor sertraline on central and peripheral serotonin neurochemistry in the rhesus monkey
Anderson GM, Barr CS, Lindell S, Durham AC, Shifrovich I, Higley JD. Time course of the effects of the serotonin-selective reuptake inhibitor sertraline on central and peripheral serotonin neurochemistry in the rhesus monkey. Psychopharmacology 2004, 178: 339-346. PMID: 15452685, DOI: 10.1007/s00213-004-2011-7.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsCisternal cerebrospinal fluid (CSF) samplesPg/Young adult male rhesus monkeysRhesus monkeysSerotonin reuptake inhibitorsAdult male rhesus monkeysPlasma drug levelsCerebrospinal fluid samplesExtent of elevationMale rhesus monkeysTime courseNon-human primatesAutoreceptor desensitizationSerotonin neurochemistryReuptake inhibitorsNeurochemical effectsResponse latencyProlonged administrationDrug levelsDrug accumulationDay 0SertralineDiscontinuationBaseline
2000
Pharmacogenetics and the serotonin system: initial studies and future directions
Veenstra-VanderWeele J, Anderson G, Cook E. Pharmacogenetics and the serotonin system: initial studies and future directions. European Journal Of Pharmacology 2000, 410: 165-181. PMID: 11134668, DOI: 10.1016/s0014-2999(00)00814-1.Peer-Reviewed Original Research
1996
Adenosine diphosphate inhibits the serotonin transporter
Anderson G, Hall L, Horne W, Yang J. Adenosine diphosphate inhibits the serotonin transporter. Biochimica Et Biophysica Acta 1996, 1283: 14-20. PMID: 8765089, DOI: 10.1016/0005-2736(96)00073-9.Peer-Reviewed Original Research
1995
Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice
Tordjman S, Roubertoux P, Carlier M, Moutier R, Anderson G, Launay M, Degrelle H. Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice. Neuroscience Letters 1995, 183: 190-192. PMID: 7739791, DOI: 10.1016/0304-3940(94)11148-c.Peer-Reviewed Original Research
1994
The role of central oxytocin in obsessive compulsive disorder and related normal behavior
Leckman J, Goodman W, North W, Chappell P, Price L, Pauls D, Anderson G, Riddle M, McDougle C, Barr L, Cohen D. The role of central oxytocin in obsessive compulsive disorder and related normal behavior. Psychoneuroendocrinology 1994, 19: 723-749. PMID: 7991761, DOI: 10.1016/0306-4530(94)90021-3.Peer-Reviewed Original ResearchConceptsForms of OCDObsessive-compulsive disorderCompulsive disorderCentral oxytocinFeatures of OCDDimensions of behaviorSeries of predictionsBehavioral symptomsOxytocinChallenge proceduresNormal behaviorSexual behaviorAnecdotal dataDisordersExtreme endsBehaviorAlternative hypothesisTreatment responseRelationship
1992
Differentiation of Neuro-2a neuroblastoma cells by an antibody to GM3 ganglioside
Chatterjee D, Chakraborty M, Anderson G. Differentiation of Neuro-2a neuroblastoma cells by an antibody to GM3 ganglioside. Brain Research 1992, 583: 31-44. PMID: 1324094, DOI: 10.1016/s0006-8993(10)80007-1.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAntibodies, MonoclonalBromodeoxyuridineBucladesineCatecholaminesCell DifferentiationCell DivisionCell LineDNA ReplicationElectrophoresis, Gel, Two-DimensionalElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueG(M3) GangliosideGangliosidesKineticsMethionineMiceModels, BiologicalMolecular WeightNeoplasm ProteinsNeuroblastomaSerotoninThymidineConceptsNeuro-2a cellsTotal cellular proteinProtein kinase A (PKA) inhibitorProtein kinase C activityInhibitors of PKCKinase C activityNeuro-2a neuroblastoma cellsCellular proteinsCellular differentiationCell surface gangliosidesElevated intracellular cAMP levelsDifferentiated cellsIntracellular cAMP levelsCyclase activityMode of actionGi proteinsProteinPKCSurface gangliosidesC activityDifferentiationAdenylate cyclase activityNeuroblastoma cellsA inhibitorsGM2 ganglioside
1991
Use of high-performance liquid chromatography for assay of glutamic acid decarboxylase Its limitation in use for post-mortem brain
Chakraborty M, Lahiri P, Anderson G, Chatterjee D. Use of high-performance liquid chromatography for assay of glutamic acid decarboxylase Its limitation in use for post-mortem brain. Journal Of Chromatography 1991, 571: 235-240. PMID: 1810951, DOI: 10.1016/0378-4347(91)80450-q.Peer-Reviewed Original Research
1988
High-performance liquid chromatographic analysis of neurotransmitter amino acids in brain
Durkin T, Anderson G, Cohen D. High-performance liquid chromatographic analysis of neurotransmitter amino acids in brain. Journal Of Chromatography 1988, 428: 9-15. PMID: 2902104, DOI: 10.1016/s0378-4347(00)83885-2.Peer-Reviewed Original Research
1987
Serotonin in cisternal cerebrospinal fluid of the rat: Measurement and use as an index of functionally active serotonin
Anderson G, Teff K, Young S. Serotonin in cisternal cerebrospinal fluid of the rat: Measurement and use as an index of functionally active serotonin. Life Sciences 1987, 40: 2253-2260. PMID: 2438530, DOI: 10.1016/0024-3205(87)90061-0.Peer-Reviewed Original ResearchAmphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups
Wool R, Weldon D, Shaywitz B, Anderson G, Cohen D, Teicher M. Amphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups. Developmental Psychobiology 1987, 20: 219-232. PMID: 3108057, DOI: 10.1002/dev.420200210.Peer-Reviewed Original ResearchConceptsBrain dopamineRat pupsCombination of desmethylimipramineD-amphetamine sulfateVehicle control solutionDays of ageTime of injectionAmphetamine treatmentControl animalsYoung ratsDesmethylimipramineLemon odorPupsDopamineOlfactory sensitivityAnimalsNovel odorOlfactory preferencesStimuliDaysExperiment IVRatsSensitization
1984
Radial arm maze performance in rats following neonatal dopamine depletion
Pearson D, Raskin L, Shywitz B, Anderson G, Cohen D. Radial arm maze performance in rats following neonatal dopamine depletion. Developmental Psychobiology 1984, 17: 505-517. PMID: 6434359, DOI: 10.1002/dev.420170508.Peer-Reviewed Original ResearchSympathetic control of sexual reflexes: Peripheral 6-hydroxydopamine administration facilitates the onset of penile reflexes in male rats
Howard S, Lumia A, Anderson G, Shaywitz B. Sympathetic control of sexual reflexes: Peripheral 6-hydroxydopamine administration facilitates the onset of penile reflexes in male rats. Physiology & Behavior 1984, 32: 791-794. PMID: 6436843, DOI: 10.1016/0031-9384(84)90196-3.Peer-Reviewed Original ResearchConceptsControl subjectsPenile reflexesMale ratsPeripheral norepinephrine levelsSympathetic inhibitionChemical sympathectomyNorepinephrine levelsSympathetic controlSexual reflexesReflexRatsMean numberSignificant differencesFirst reflexAdministrationOne daySubjectsSalineDaysTreatmentOnsetSympathectomy
1983
Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup
Shaywitz B, Teicher M, Cohen D, Anderson G, Young J, Levitt P. Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup. Psychopharmacology 1983, 82: 73-77. PMID: 6420833, DOI: 10.1007/bf00426384.Peer-Reviewed Original ResearchConceptsRat pupsDays of ageMotor activityBehavioral arousalPostsynaptic dopaminergic mechanismsReduction of norepinephrineReduction of dopamineGeneral motor activityMesolimbic dopaminergic pathwayDopaminergic mechanismsBrain dopaminePreferential reductionEscape latencyNoradrenergic mediationNorepinephrinePostnatal lifeWeek 3PupsSuch treatmentDopamineT-mazeShuttle boxAgeDesmethylimipraminePerformance deficitsDifferential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat
Raskin L, Shaywitz B, Anderson G, Cohen D, Teicher M, Linakis J. Differential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat. Pharmacology Biochemistry And Behavior 1983, 19: 743-749. PMID: 6647508, DOI: 10.1016/0091-3057(83)90073-4.Peer-Reviewed Original ResearchConceptsDays of ageT-mazeCentral catecholamine systemsSelective dopamine depletionSelective norepinephrine depletionDopamine depletionNE levelsNorepinephrine depletionCatecholamine depletionSevere learning impairmentIntraperitoneal injectionCatecholamine systemsSelective lesionsDay 28Selective dopamineNeonatal depletionLearning impairmentSelective depletionCatecholaminesClinical researchBehavioral effectsDeficit disorderShuttlebox performanceActivity levelsConstellation of behaviors
1982
Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups
Weldon D, Wool R, Teicher M, Shaywitz B, Cohen D, Anderson G. Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups. Pharmacology Biochemistry And Behavior 1982, 17: 1281-1284. PMID: 6819587, DOI: 10.1016/0091-3057(82)90134-4.Peer-Reviewed Original ResearchConceptsApomorphine administrationRat pupsCombination of desmethylimipramineEffects of apomorphinePostnatal day 5Brain dopamineControl injectionsDrug treatmentNormal pupsIsotonic salineDay 5Appetitive responsesPupsImpaired performanceNext dayDesmethylimipramineApomorphineBaby formulaAnise odorAppetitive conditioningAdministrationSalineDopamineNovel odorAnimalsEnvironmental and biologic interactions on behavior: Effects of artificial rearing in rat pups treated with 6‐hydroxydopamine
Goldenring J, Shaywitz B, Wool R, Batter D, Anderson G, Cohen D. Environmental and biologic interactions on behavior: Effects of artificial rearing in rat pups treated with 6‐hydroxydopamine. Developmental Psychobiology 1982, 15: 297-307. PMID: 6809512, DOI: 10.1002/dev.420150403.Peer-Reviewed Original ResearchClinical neurochemistry of autism and associated disorders
Young J, Kavanagh M, Anderson G, Shaywitz B, Cohen D. Clinical neurochemistry of autism and associated disorders. Journal Of Autism And Developmental Disorders 1982, 12: 147-165. PMID: 6184361, DOI: 10.1007/bf01531305.Peer-Reviewed Original ResearchConceptsNorepinephrine metabolismNeurochemical methodsClinical neurochemistryClinical studiesNeurochemical studiesBehavioral deficitsBiochemical dysfunctionBrain functionAutistic syndromeInfantile autismLow levelsNew studiesAutismDysfunctionSerotoninSyndromeAutistic individualsSymptomsNeurochemistryBrainMajor obstacleDetermination of indoles in human and rat pineal
Anderson G, Young J, Cohen D, Young S. Determination of indoles in human and rat pineal. Journal Of Chromatography 1982, 228: 155-163. PMID: 6176588, DOI: 10.1016/s0378-4347(00)80428-4.Peer-Reviewed Original ResearchFactors Influencing Melatonin, 5-Hydroxytryptophol, 5-Hydroxyindoleacetic Acid, 5-Hydroxytryptamine and Tryptophan in Rat Pineal Glands
Young S, Anderson G. Factors Influencing Melatonin, 5-Hydroxytryptophol, 5-Hydroxyindoleacetic Acid, 5-Hydroxytryptamine and Tryptophan in Rat Pineal Glands. Neuroendocrinology 1982, 35: 464-468. PMID: 6185873, DOI: 10.1159/000123423.Peer-Reviewed Original Research