2000
Adrenomedullary Function During Cognitive Testing in Attention-Deficit/Hyperactivity Disorder
ANDERSON G, DOVER M, YANG B, HOLAHAN J, SHAYWITZ S, MARCHIONE K, HALL L, FLETCHER J, SHAYWITZ B. Adrenomedullary Function During Cognitive Testing in Attention-Deficit/Hyperactivity Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2000, 39: 635-643. PMID: 10802982, DOI: 10.1097/00004583-200005000-00018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenal MedullaAttention Deficit Disorder with HyperactivityCatecholaminesChildCognition DisordersEpinephrineHumansMaleNeuropsychological TestsNorepinephrinePredictive Value of TestsPsychiatric Status Rating ScalesConceptsAttention-deficit/hyperactivity disorderEPI excretionHyperactivity disorderCognitive testingOppositional defiant/conduct disorderCognitive test batteryADHD inattentive subtypeTeacher-rated behaviorDiagnostic group differencesCognition-enhancing effectsInattentive behaviorCognitive challengesLearning disorderInattention factorTest batteryConduct disorderCorrelational analysisGroup differencesClassroom performanceContrast groupSympathoadrenomedullary functionDisordersBoysIndividualsFunctioning
1994
Aspartame, behavior, and cognitive function in children with attention deficit disorder.
Shaywitz B, Sullivan C, Anderson G, Gillespie S, Sullivan B, Shaywitz S. Aspartame, behavior, and cognitive function in children with attention deficit disorder. Pediatrics 1994, 93: 70-5. PMID: 7505423, DOI: 10.1542/peds.93.1.70.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAspartameAttention Deficit Disorder with HyperactivityCatecholaminesChildChild BehaviorChild, PreschoolCognitionDouble-Blind MethodFemaleHomovanillic AcidHumansHydroxyindoleacetic AcidMalePhenylalanineConceptsAttention deficit disorderWisconsin Card Sorting TestDeficit disorderTreatment Emergent Symptom ScalePlacebo-controlled crossover studyComplete blood cell countStudy centersLiver function testsUrinary excretion rateBlood cell countAdministration of aspartameMental Disorders criteriaCognitive testsMeasurement of catecholaminesCrossover studyFunction testsMonoamine metabolismInpatient admissionsMetabolite excretionLarge dosesSymptom ScaleUsual consumptionCell countPlasma phenylalanineBiochemical measures
1990
Growth hormone and prolactin response to methylphenidate in children with attention deficit disorder
Shaywitz B, Shaywitz S, Sebrechts M, Anderson G, Cohen D, Jatlow P, Young J. Growth hormone and prolactin response to methylphenidate in children with attention deficit disorder. Life Sciences 1990, 46: 625-633. PMID: 2308471, DOI: 10.1016/0024-3205(90)90131-a.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityChildChild BehaviorDouble-Blind MethodGrowth HormoneHumansMaleMethylphenidateProlactinPsychological Tests
1988
Plasma MHPG: Within- and across-day stability in children and adults with tourette's syndrome
Riddle M, Leckman J, Anderson G, Ort S, Hardin M, Stevenson J, Cohen D. Plasma MHPG: Within- and across-day stability in children and adults with tourette's syndrome. Biological Psychiatry 1988, 24: 391-398. PMID: 2457395, DOI: 10.1016/0006-3223(88)90175-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAttention Deficit Disorder with HyperactivityChildCircadian RhythmDevelopmental DisabilitiesFemaleGlycolsHumansMaleMethoxyhydroxyphenylglycolMiddle AgedObsessive-Compulsive DisorderSex FactorsTourette Syndrome
1987
Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation
COHEN D, ORT S, CARUSO K, ANDERSON G, HUNT R, SHAYWITZ B, KREMENITZER M, LECKMAN J. Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation. Journal Of The American Academy Of Child & Adolescent Psychiatry 1987, 26: 65-68. PMID: 3034852, DOI: 10.1097/00004583-198701000-00013.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildClonidineFemaleHumansMaleParotid GlandReceptors, AdrenergicTourette SyndromeConceptsAttention deficit disorderTourette syndromeSalivary amylase concentrationTS patientsAmylase concentrationSalivary secretionNeurochemical regulationReceptor functioningTreatment of TSDeficit disorderSalivary amylase secretionParotid gland secretionSingle dosesSalivary volumeClonidinePatientsAmylase secretionSyndromeADD patientsSalivary measuresSecretionTotal amylaseSalivary amylaseDisordersChildren
1986
Brief debrisoquin administration to assess central dopaminergic function in children
Riddle M, Shaywitz B, Leckman J, Anderson G, Shaywitz S, Hardin M, Ort S, Cohen D. Brief debrisoquin administration to assess central dopaminergic function in children. Life Sciences 1986, 38: 1041-1048. PMID: 3456480, DOI: 10.1016/0024-3205(86)90239-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildDebrisoquinDopamineFemaleHomovanillic AcidHumansIsoquinolinesKineticsMaleTourette SyndromeConceptsCentral dopaminergic functionDopaminergic functionHomovanillic acid levelsBehavioral side effectsActive antihypertensive agentDebrisoquin sulfatePHVA levelsAntihypertensive agentsSix-hour periodSide effectsBrief administrationNeuropsychiatric disordersAdministration methodsMarked reductionPeripheral techniquesAcid levelsAdministrationPatientsChildrenDebrisoquinPHVAComponents of attention, methylphenidate dosage, and blood levels in children with attention deficit disorder.
Sebrechts M, Shaywitz S, Shaywitz B, Jatlow P, Anderson G, Cohen D. Components of attention, methylphenidate dosage, and blood levels in children with attention deficit disorder. Pediatrics 1986, 77: 222-8. PMID: 3945535, DOI: 10.1542/peds.77.2.222.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttentionAttention Deficit Disorder with HyperactivityChildChild BehaviorDouble-Blind MethodDrug Administration ScheduleHumansImpulsive BehaviorIndividualityMaleMemoryMethylphenidateReadingConceptsAttention deficit disorderDeficit disorderComponents of attentionDoses of methylphenidateCognitive resourcesCognitive componentsAttentional deficitsParent ratingsMethylphenidate dosageTest batteryMethylphenidateChildrenDisordersTaskDeficitsRatingsSingle testAttentionPerformanceTeachersBlood levelsBatteries
1984
Neurochemical Correlates of Attention Deficit Disorder
Raskin L, Shaywitz S, Shaywitz B, Anderson G, Cohen D. Neurochemical Correlates of Attention Deficit Disorder. Pediatric Clinics Of North America 1984, 31: 387-396. PMID: 6728523, DOI: 10.1016/s0031-3955(16)34584-9.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityChildDextroamphetamineDopamineHumansMethoxyhydroxyphenylglycolMethylphenidateNorepinephrineSerotonin
1982
Psychopharmacology of attention deficit disorder: pharmacokinetic, neuroendocrine, and behavioral measures following acute and chronic treatment with methylphenidate.
Shaywitz S, Hunt R, Jatlow P, Cohen D, Young J, Pierce R, Anderson G, Shaywitz B. Psychopharmacology of attention deficit disorder: pharmacokinetic, neuroendocrine, and behavioral measures following acute and chronic treatment with methylphenidate. Pediatrics 1982, 69: 688-94. PMID: 7079034, DOI: 10.1542/peds.69.6.688.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityChildGrowth HormoneHumansKineticsMaleMethylphenidateModels, BiologicalProlactinTime FactorsConceptsAcute studyMPH concentrationsGrowth hormoneObserved maximal concentrationCentral dopaminergic mechanismsPeak plasma concentrationAdministration of medicationsPharmacokinetics of methylphenidatePlasma growth hormoneConcentrations of methylphenidatePlasma MPH concentrationsAttention deficit disorderClinical responseChronic treatmentDopaminergic mechanismsGroup of childrenDisorders of attentionAbbreviated Conners' Rating ScaleSchool-aged childrenOral administrationPlasma concentrationsClinical pharmacologyMPH administrationProlactin concentrationsPercentage of improvement