2024
Maternal Serotonin Levels and Neurodevelopmental Severity in Autistic Children: A Partial Replication and Extension
Jutla A, Shuffrey L, Guter S, Anderson G, O’Reilly K, Montgomery A, Sutcliffe J, Cook E, Veenstra-VanderWeele J. Maternal Serotonin Levels and Neurodevelopmental Severity in Autistic Children: A Partial Replication and Extension. JAACAP Open 2024 DOI: 10.1016/j.jaacop.2024.09.005.Peer-Reviewed Original ResearchLatent profile analysisSevere profileAdaptive functioningAssociated with social impairmentAutistic childrenAutism symptom severityAutism spectrum disorderNonverbal IQSerotonin systemSocial impairmentAutistic traitsRepetitive behaviorsSerotonin levelsSymptom severityHigh-severity groupSpectrum disorderPartial replicationGroup levelSevere groupExploratory modelProfile analysisChildrenStratified participantsSeveritySerotoninLong COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration
Anderson G, Cook E, Blakely R, Sutcliffe J, Veenstra-VanderWeele J. Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration. Journal Of Inflammation Research 2024, 17: 2169-2172. PMID: 38628604, PMCID: PMC11019386, DOI: 10.2147/jir.s456000.Peer-Reviewed Original ResearchPlatelet serotoninSerotonin valuesTrials of SSRIsSerotonin reuptake inhibitorsPlatelet serotonin transportersSerotonin reductionSSRI administrationSSRI treatmentReuptake inhibitorsSerotonin transporterMemory impairmentSerotonin levelsSSRIsSerotoninDepletion of plateletsPlasma serotoninPeripheral serotoninSequelae of COVID-19Viremia patientsCardiovascular sequelaeCirculating serotoninHyperaggregable stateTreatment of COVID-19Clinical trialsLong COVID
2017
4.12 Maternal Whole Blood Serotonin Levels Predict Verbal Ability and Core Symptoms in Children With Autism Spectrum Disorder
Montgomery A, Shuffrey L, Guter S, Anderson G, Jacob S, Sutcliffe J, Turner J, Cook E, Veenstra-VanderWeele J. 4.12 Maternal Whole Blood Serotonin Levels Predict Verbal Ability and Core Symptoms in Children With Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2017, 56: s232. DOI: 10.1016/j.jaac.2017.09.228.Peer-Reviewed Original Research
1998
Tryptophan Depletion During Continuous CSF Sampling in Healthy Human Subjects
Carpenter L, Anderson G, Pelton G, Gudin J, Kirwin P, Price L, Heninger G, McDougle C. Tryptophan Depletion During Continuous CSF Sampling in Healthy Human Subjects. Neuropsychopharmacology 1998, 19: 26-35. PMID: 9608574, DOI: 10.1016/s0893-133x(97)00198-x.Peer-Reviewed Original ResearchConceptsAmino acid drinkCerebrospinal fluidAcid drinkTRP levelsLow TRP dietTryptophan depletion paradigmBrain serotonin levelsPlasma TRP levelsHealthy adult subjectsHealthy human subjectsCSF TRP levelsPlasma TrpIndwelling catheterLumbar punctureSerotonin levelsTryptophan depletionContinuous cerebrospinal fluidSpecial dietAdult subjectsBehavioral effectsPlasma samplesHuman subjectsCorresponding fallCentral levelNadir
1995
Plasma androgens in autism
Tordjman S, Anderson G, McBride P, Hertzig M, Snow M, Hall L, Ferrari P, Cohen D. Plasma androgens in autism. Journal Of Autism And Developmental Disorders 1995, 25: 295-304. PMID: 7559294, DOI: 10.1007/bf02179290.Peer-Reviewed Original ResearchConceptsCerebral palsyPlasma DHEA-S levelsNC individualsAdrenal androgen secretionDHEA-S levelsAdrenal androgen dehydroepiandrosterone sulfateBlood serotonin levelsNormal control subjectsWhole blood serotonin levelsEffect of pubertySignificant group differencesAndrogen secretionDehydroepiandrosterone sulfateControl subjectsPlasma levelsSerotonin levelsNC groupPlasma androgensPlasma testosteroneSignificant negative correlationTestosteroneImpaired subjectsWhole bloodMean levelsGroup differencesLinkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice
Tordjman S, Roubertoux P, Carlier M, Moutier R, Anderson G, Launay M, Degrelle H. Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice. Neuroscience Letters 1995, 183: 190-192. PMID: 7739791, DOI: 10.1016/0304-3940(94)11148-c.Peer-Reviewed Original Research
1992
Platelet and whole blood serotonin content in depressed inpatients: Correlations with acute and life-time psychopathology
Mann J, McBride P, Anderson G, Mieczkowski T. Platelet and whole blood serotonin content in depressed inpatients: Correlations with acute and life-time psychopathology. Biological Psychiatry 1992, 32: 243-257. PMID: 1420642, DOI: 10.1016/0006-3223(92)90106-a.Peer-Reviewed Original ResearchConceptsPlatelet serotonin contentBorderline personality disorderBlood serotonin contentSerotonin contentWhole blood serotonin contentSerotonin levelsHealthy controlsPersonality disorderLower platelet serotonin contentComorbid borderline personality disorderHigher serotonin levelsLow serotonin levelsSeverity of depressionPlatelet serotonin levelsLife-time historyBPD attemptersPatient groupMajor depressionPatientsDepressed inpatientsSuicide attemptsSuicidal behaviorNonborderline patientsWhole bloodDisorders
1987
WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS
Anderson G, Freedman D, Cohen D, Volkmar F, Hoder E, McPhedran P, Minderaa R, Hansen C, Young J. WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS. Journal Of Child Psychology And Psychiatry 1987, 28: 885-900. PMID: 3436995, DOI: 10.1111/j.1469-7610.1987.tb00677.x.Peer-Reviewed Original ResearchConceptsWhole blood serotoninSerotonin levelsBlood serotoninNormal subjectsWhole blood serotonin concentrationAutistic subjectsBlood serotonin concentrationsBlood tryptophan levelsLow serotonin levelsHyperserotonemia of autismPlatelet countSerotonin concentrationsNormal groupTryptophan levelsSerotoninAutistic groupSubjectsPossible causesAnticonvulsantsNeurolepticsGroupLevelsHyperserotonemia
1985
Effect of a Meal on Human Whole Blood Serotonin
Anderson G, Feibel F, Wetlaufer L, Schlicht K, Ort S, Cohen D. Effect of a Meal on Human Whole Blood Serotonin. Gastroenterology 1985, 88: 86-89. PMID: 2578039, DOI: 10.1016/s0016-5085(85)80137-2.Peer-Reviewed Original ResearchConceptsWhole blood serotoninMicrograms/hBlood serotoninGastrointestinal hormonesUrinary excretionSerotonin levelsBlood samplesUrine specimensBaseline levelsSerotoninSecond hourWhole bloodHuman subjectsSpecific high-performance liquid chromatographic methodMealMinSubjectsUrinaryLevelsExcretionBloodHormone