1994
Noradrenergic and adrenergic functioning in autism
Minderaa R, Anderson G, Volkmar F, Akkerhuis G, Cohen D. Noradrenergic and adrenergic functioning in autism. Biological Psychiatry 1994, 36: 237-241. PMID: 7986888, DOI: 10.1016/0006-3223(94)90605-x.Peer-Reviewed Original ResearchConceptsUrinary excretion rateNeurochemical assessmentVanillylmandelic acidAdrenergic functioningExcretion rateNormal control individualsUrinary excretionPlasma levelsNoradrenergic functioningMarked abnormalitiesNormal controlsGroup mean differencesControl groupControl individualsNorepinephrineMean differenceAutistic patients
1986
Rebound Phenomena in Tourette's Syndrome After Abrupt Withdrawal of Clonidine: Behavioral, Cardiovascular, and Neurochemical Effects
Leckman J, Ort S, Caruso K, Anderson G, Riddle M, Cohen D. Rebound Phenomena in Tourette's Syndrome After Abrupt Withdrawal of Clonidine: Behavioral, Cardiovascular, and Neurochemical Effects. JAMA Psychiatry 1986, 43: 1168-1176. PMID: 3465278, DOI: 10.1001/archpsyc.1986.01800120054011.Peer-Reviewed Original ResearchConceptsTourette syndromeNeurochemical effectsAbrupt withdrawalWorsening of ticsClonidine therapyClonidine withdrawalClonidine's effectivenessAdrenergic mechanismsBlood pressureOpen trialTic symptomsUrinary excretionPlasma levelsMotor restlessnessHomovanillic acidClonidine hydrochlorideSyndromeWithdrawal periodPrewithdrawal levelsRebound phenomenonPatientsPulse rateClonidineWithdrawalNorepinephrine
1985
NEUROTRANSMITTER PRECURSORS and METABOLITES IN CSF OF HUMAN NEONATES
Anderson G, Hoder E, Shaywitz B, Cohen D. NEUROTRANSMITTER PRECURSORS and METABOLITES IN CSF OF HUMAN NEONATES. Developmental Medicine & Child Neurology 1985, 27: 207-214. PMID: 2581835, DOI: 10.1111/j.1469-8749.1985.tb03771.x.Peer-Reviewed Original ResearchConceptsHuman neonatesAmino acid precursor tryptophanSignificant subgroup differencesMedical complicationsHomovanillic acidCerebrospinal fluidNeurotransmitter precursorsPrecursor tryptophanNeurotransmitter serotoninOlder childrenMajor metaboliteComplicated groupLatter groupComplicationsSignificant correlationNeonatesSubgroup differencesInfantsPhysiological measuresGroupMetabolitesLarge groupHigh levelsMedicationsNorepinephrineCerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup
Shaywitz B, Anderson G, Cohen D. Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup. Brain Research 1985, 17: 225-232. DOI: 10.1016/0165-3806(85)90146-4.Peer-Reviewed Original Research
1983
Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup
Shaywitz B, Teicher M, Cohen D, Anderson G, Young J, Levitt P. Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup. Psychopharmacology 1983, 82: 73-77. PMID: 6420833, DOI: 10.1007/bf00426384.Peer-Reviewed Original ResearchConceptsRat pupsDays of ageMotor activityBehavioral arousalPostsynaptic dopaminergic mechanismsReduction of norepinephrineReduction of dopamineGeneral motor activityMesolimbic dopaminergic pathwayDopaminergic mechanismsBrain dopaminePreferential reductionEscape latencyNoradrenergic mediationNorepinephrinePostnatal lifeWeek 3PupsSuch treatmentDopamineT-mazeShuttle boxAgeDesmethylimipraminePerformance deficits
1980
Simplified liquid chromatographic—electrochemical determination of norepinephrine and dopamine in rat brain
Anderson G, Batter D, Young J, Shaywitz B, Cohen D. Simplified liquid chromatographic—electrochemical determination of norepinephrine and dopamine in rat brain. Journal Of Chromatography 1980, 181: 453-455. PMID: 7391159, DOI: 10.1016/s0378-4347(00)81148-2.Peer-Reviewed Original Research