2005
Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder
Tordjman S, Anderson GM, Pichard N, Charbuy H, Touitou Y. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biological Psychiatry 2005, 57: 134-138. PMID: 15652871, DOI: 10.1016/j.biopsych.2004.11.003.Peer-Reviewed Original ResearchConceptsAutistic disorderNocturnal urinary excretionPineal gland hormoneLow melatonin productionNormal control individualsMelatonin physiologyGroup of childrenUrinary excretionMelatonin administrationTanner stageSleep problemsNormal controlsReported alterationNocturnal excretionControl individualsExcretion rateDisordersGland hormoneMelatoninMelatonin productionAutistic impairmentsExcretionCircadian rhythmBehavioral expressionVerbal communication
1994
Noradrenergic and adrenergic functioning in autism
Minderaa R, Anderson G, Volkmar F, Akkerhuis G, Cohen D. Noradrenergic and adrenergic functioning in autism. Biological Psychiatry 1994, 36: 237-241. PMID: 7986888, DOI: 10.1016/0006-3223(94)90605-x.Peer-Reviewed Original ResearchConceptsUrinary excretion rateNeurochemical assessmentVanillylmandelic acidAdrenergic functioningExcretion rateNormal control individualsUrinary excretionPlasma levelsNoradrenergic functioningMarked abnormalitiesNormal controlsGroup mean differencesControl groupControl individualsNorepinephrineMean differenceAutistic patients
1989
Neurochemical Study of Dopamine Functioning in Autistic and Normal Subjects
MINDERAA R, ANDERSON G, VOLKMAR F, AKKERHUIS G, COHEN D. Neurochemical Study of Dopamine Functioning in Autistic and Normal Subjects. Journal Of The American Academy Of Child & Adolescent Psychiatry 1989, 28: 190-194. PMID: 2925571, DOI: 10.1097/00004583-198903000-00007.Peer-Reviewed Original ResearchConceptsPlasma PRLPlasma prolactinHVA levelsUrinary HVANormal controlsNormal subjectsUrinary DA excretionUrinary HVA excretionHomovanillic acid levelsDose of neurolepticPlasma PRL valuesDopamine functioningDopamine excretionNeuroleptic doseHVA excretionNeuroleptic medicationDA excretionNeurochemical studiesPRL valuesPeripheral indicesExcretion rateAcid levelsHVAExcretionSignificant differences