2009
Zoledronate reduces unwanted bone resorption in intercalary bone allografts
Seo SW, Cho SK, Storer SK, Lee FY. Zoledronate reduces unwanted bone resorption in intercalary bone allografts. International Orthopaedics 2009, 34: 599-603. PMID: 19343345, PMCID: PMC2903128, DOI: 10.1007/s00264-009-0748-7.Peer-Reviewed Original ResearchConceptsAllograft resorptionIntercalary allograftsBone resorptionBone allograftControl groupZoledronate solutionIntercalary bone allograftsBone formationBone mineral densitySynthetic pyrophosphate analoguesHigh-dose bisphosphonatesPharmacological modificationGraft incorporationMineral densityBone densityAllograftsIdeal doseResorptionAnimal trialsHistological analysisBisphosphonatesSegmental defectsPyrophosphate analogsExperimental groupRat femur
2004
Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP).
Delloye C, Suratwala SJ, Cornu O, Lee FY. Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP). Acta Orthopaedica Belgica 2004, 70: 591-7. PMID: 15669462.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBone Morphogenetic ProteinsBone NeoplasmsBone TransplantationFemaleFollow-Up StudiesFractures, UnunitedHumansMaleMiddle AgedOsteosarcomaRadiographyRetrospective StudiesRisk AssessmentSampling StudiesSarcoma, EwingSensitivity and SpecificityTransplantation, HomologousTreatment OutcomeConceptsAllograft-host junctionAllograft nonunionRecombinant human bone morphogenetic proteinAllograft fractureIntercalary allograftsFracture nonunionHuman bone morphogenetic proteinAdditional radiation therapyMalignant bone tumorsRhBMP-7Allograft bone transplantationBone morphogenetic proteinAdjuvant chemotherapySterile drainageRadiological evidenceCorticocancellous allograftFemoral allograftsTibial nonunionWide resectionOsteoarticular allograftsTumor recurrenceMain complicationsNonunion siteBone tumorsRadiation therapy
2000
Experimental model for allograft incorporation and allograft fracture repair
Lee F, Hazan E, Gebhardt M, Mankin H. Experimental model for allograft incorporation and allograft fracture repair. Journal Of Orthopaedic Research® 2000, 18: 303-306. PMID: 10815832, DOI: 10.1002/jor.1100180219.Peer-Reviewed Original ResearchConceptsAllograft incorporationFracture repairHost-donor interfaceSprague-Dawley ratsSkeletal defectsAdult LewisImmediate ambulationIntercalary allograftsRat modelHistological examinationOsteotomy healingKirschner wiresMuscle layerOsteotomy siteTransverse osteotomyExperimental modelHealing processAllograftsRepair processRepairAmbulation