2022
Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population
Santiago C, Peña M, Brown T, Shakil S, Januzzi J, Velazquez E, Miranda J, Rivera D, Checkley W. Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population. Global Heart 2022, 17: 78. PMID: 36382157, PMCID: PMC9615600, DOI: 10.5334/gh.981.Peer-Reviewed Original ResearchConceptsSignificant depressive symptomsDepressive symptomsHeart failureCardiac structureTransthoracic echocardiographyEpidemiological Studies Depression ScaleCRONICAS Cohort StudyDiastolic relaxation velocityCause of disabilityMultivariable linear regressionNon-depressed subjectsCohort studyEchocardiographic measuresMiddle-income countriesWorse outcomesDepressive disorderDepression ScaleCardiac diseaseRelaxation velocityDepression symptomsNon-depressed participantsSymptomsPeruvian populationRelevant covariatesAdult participants
2018
Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL
Peña M, Swett K, Kaplan RC, Perreira K, Daviglus M, Kansal MM, Cai J, Giachello AL, Gellman MD, Velazquez EJ, Rodriguez CJ. Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL. Open Heart 2018, 5: e000831. PMID: 30402256, PMCID: PMC6203071, DOI: 10.1136/openhrt-2018-000831.Peer-Reviewed Original ResearchLeft ventricular global longitudinal strainLeft ventricular ejection fractionIsovolumic relaxation timeSHS exposureCardiac structureTobacco smokersRight ventricular fractional area changeVentricular global longitudinal strainVentricular fractional area changeHousehold SHS exposureAtrial volume indexClinical heart failureSevere valvular diseaseVentricular ejection fractionCoronary artery diseaseGlobal longitudinal strainSecondhand smoke exposureFractional area changeHousehold secondhand smoke exposureAdolescents/adultsECHO-SOLArtery diseaseCardiac systolicDiastolic functionEchocardiographic measures
2011
Incremental value of echocardiographic assessment beyond clinical evaluation for prediction of death and development of heart failure after high-risk myocardial infarction
Verma A, Pfeffer MA, Skali H, Rouleau J, Maggioni A, McMurray JJ, Califf RM, Velazquez EJ, Solomon SD. Incremental value of echocardiographic assessment beyond clinical evaluation for prediction of death and development of heart failure after high-risk myocardial infarction. American Heart Journal 2011, 161: 1156-1162. PMID: 21641363, DOI: 10.1016/j.ahj.2011.03.024.Peer-Reviewed Original ResearchConceptsLV ejection fractionHigh-risk myocardial infarctionOutcome of deathHeart failureEchocardiographic measuresMyocardial infarctionEchocardiographic assessmentEjection fractionPrognostic valueClinical variablesClinical assessmentPredictive valueRight ventricular fractional area changeMultivariable proportional hazards modelsVentricular fractional area changeLeft ventricular ejection fractionMinimal prognostic valueAtrial volume indexIncremental prognostic valuePredictors of deathVentricular mass indexVentricular ejection fractionLeft ventricular functionPrediction of deathImportant prognostic information
2010
Longitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction
Hung CL, Verma A, Uno H, Shin SH, Bourgoun M, Hassanein AH, McMurray JJ, Velazquez EJ, Kober L, Pfeffer MA, Solomon SD, Investigators V. Longitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction. Journal Of The American College Of Cardiology 2010, 56: 1812-1822. PMID: 21087709, DOI: 10.1016/j.jacc.2010.06.044.Peer-Reviewed Original ResearchConceptsCircumferential SRMyocardial infarctionHeart failureLongitudinal SRHigh-risk myocardial infarctionVALIANT Echo studyLong-term outcomesMultivariable logistic regressionStandard echocardiographic measuresClinical prognostic valueVentricular contractile performanceCox proportional hazardsParasternal short-axis viewCircumferential strain rateSpeckle-tracking softwareShort-axis viewHospital stayLV dysfunctionSystolic functionEchocardiographic measuresIndependent predictorsClinical outcomesVentricular enlargementPrognostic valueSystolic SR
2008
Emerging Role of Myocardial Perfusion Imaging to Evaluate Patients for Cardiac Resynchronization Therapy††Conflicts of interest: Dr. Garcia has an ownership interest in and serves as a consultant and advisory board member for Syntermed, Inc., Atlanta, Georgia. Dr. Garcia also receives royalties from the sale of clinical software that was used as part of this research. Dr. Borges-Neto and Dr. Trimble have received research support from the Duke-Medtronic Strategic Alliance, which funded some of the studies reviewed in this report.
Trimble MA, Borges-Neto S, Velazquez EJ, Chen J, Shaw LK, Pagnanelli R, Garcia EV, Iskandrian AE. Emerging Role of Myocardial Perfusion Imaging to Evaluate Patients for Cardiac Resynchronization Therapy††Conflicts of interest: Dr. Garcia has an ownership interest in and serves as a consultant and advisory board member for Syntermed, Inc., Atlanta, Georgia. Dr. Garcia also receives royalties from the sale of clinical software that was used as part of this research. Dr. Borges-Neto and Dr. Trimble have received research support from the Duke-Medtronic Strategic Alliance, which funded some of the studies reviewed in this report. The American Journal Of Cardiology 2008, 102: 211-217. PMID: 18602524, DOI: 10.1016/j.amjcard.2008.03.043.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyMechanical dyssynchronyElectrical dyssynchronyMyocardial perfusionSignificant heart failure symptomsTomographic myocardial perfusion imagingLV functional improvementHeart failure symptomsLV systolic dysfunctionSevere LV dysfunctionSelection of patientsManagement of patientsLV mechanical dyssynchronyLeft ventricular dyssynchronyMyocardial perfusion imagingCurrent selection criteriaLV dysfunctionSystolic dysfunctionEchocardiographic measuresResynchronization therapyVentricular dyssynchronyCardiac resynchronizationClinical statusLV remodelingFailure symptoms
2005
Changes in Ventricular Size and Function in Patients Treated With Valsartan, Captopril, or Both After Myocardial Infarction
Solomon SD, Skali H, Anavekar NS, Bourgoun M, Barvik S, Ghali JK, Warnica JW, Khrakovskaya M, Arnold JM, Schwartz Y, Velazquez EJ, Califf RM, McMurray JV, Pfeffer MA. Changes in Ventricular Size and Function in Patients Treated With Valsartan, Captopril, or Both After Myocardial Infarction. Circulation 2005, 111: 3411-3419. PMID: 15967846, DOI: 10.1161/circulationaha.104.508093.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiotensin-Converting Enzyme InhibitorsCaptoprilDrug Therapy, CombinationElectrocardiographyFemaleHeart VentriclesHospitalizationHumansHypertrophy, Left VentricularMaleMiddle AgedMyocardial InfarctionPrognosisStroke VolumeTetrazolesTreatment OutcomeValineValsartanVentricular Dysfunction, LeftConceptsAngiotensin receptor blockersMyocardial infarctionEjection fractionEchocardiographic measuresPo bidPo tidHeart failureTreatment armsInfarct segment lengthProgressive LV enlargementVALIANT Echo studyLV ejection fractionLeft ventricular enlargementCombination of captoprilACE inhibitor captoprilEnd-diastolic volumeARB valsartanEchocardiographic characteristicsVALIANT studyCardiovascular eventsEchocardiographic parametersLV dysfunctionReceptor blockersLV enlargementVentricular enlargement
2004
Importance of echocardiography in patients with severe nonischemic heart failure: the second prospective randomized amlodipine survival evaluation (PRAISE-2) echocardiographic study
Cabell CH, Trichon BH, Velazquez EJ, Dumesnil JG, Anstrom KJ, Ryan T, Miller AB, Belkin RN, Cropp AB, O'Connor CM, Jollis JG. Importance of echocardiography in patients with severe nonischemic heart failure: the second prospective randomized amlodipine survival evaluation (PRAISE-2) echocardiographic study. American Heart Journal 2004, 147: 151-157. PMID: 14691434, DOI: 10.1016/j.ahj.2003.07.010.Peer-Reviewed Original ResearchConceptsHeart failureEchocardiographic studyEchocardiographic parametersNonischemic cardiomyopathyEchocardiographic examinationPrognostic informationClinical informationRestrictive left ventricular filling patternLeft ventricular filling patternSevere nonischemic heart failureAvailable echocardiographic parametersBaseline clinical findingsVentricular filling patternSignificant clinical predictorsIncremental prognostic informationClinical examination findingsImportance of echocardiographyNonischemic heart failureVentricular ejection fractionEchocardiographic predictorsClinical predictorsEchocardiographic measuresEjection fractionExamination findingsClinical findings