2013
Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors
Nunes E, Randall P, Podurgiel S, Correa M, Salamone J. Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors. Neuroscience & Biobehavioral Reviews 2013, 37: 2015-2025. PMID: 23583616, DOI: 10.1016/j.neubiorev.2013.04.002.Peer-Reviewed Original ResearchConceptsEffort-related choice behaviorMuscarinic acetylcholine receptorsDA antagonismEffort-related processesNAc coreAcetylcholine receptorsFood motivationAspects of appetiteControl site dorsalPrimary food motivationA2A receptor stimulationMuscarinic antagonist scopolamineDA D2 antagonistsAction of pilocarpineAdenosine A2A receptorsAdenosine A2A antagonistsEffects of drugsEffort-related choiceFood-seeking behaviorSites dorsalChow intakeDA depletionDA transmissionMuscarinic receptorsD2 antagonist
2012
THE BEHAVIORAL PHARMACOLOGY OF EFFORT‐RELATED CHOICE BEHAVIOR: DOPAMINE, ADENOSINE AND BEYOND
Salamone J, Correa M, Nunes E, Randall P, Pardo M. THE BEHAVIORAL PHARMACOLOGY OF EFFORT‐RELATED CHOICE BEHAVIOR: DOPAMINE, ADENOSINE AND BEYOND. Journal Of The Experimental Analysis Of Behavior 2012, 97: 125-146. PMID: 22287808, PMCID: PMC3266736, DOI: 10.1901/jeab.2012.97-125.Peer-Reviewed Original ResearchConceptsEffort-related choice behaviorDA depletionAccumbens DA depletionsNucleus accumbens DAAccumbens DAFood-reinforced behaviorDA transmissionMesolimbic DAPsychomotor slowingEffort-related functionsNeurological disordersFood-reinforced tasksBrain structuresDrug abuseAccumbens DA transmissionBehavioral pharmacologyHigh response requirementsRatsBrain systemsPresent reviewPrimary reinforcerAntagonism
2010
Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors
Farrar A, Segovia K, Randall P, Nunes E, Collins L, Stopper C, Port R, Hockemeyer J, Müller C, Correa M, Salamone J. Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors. Neuroscience 2010, 166: 1056-1067. PMID: 20096336, DOI: 10.1016/j.neuroscience.2009.12.056.Peer-Reviewed Original Research