2020
Effect of Concurrent Dementia on Heart Failure Hospital Outcomes: Nationwide Inpatient Sample (2007–2014)
Vuong J, Akintoye E, Kim S, Desai A, Dorbala S. Effect of Concurrent Dementia on Heart Failure Hospital Outcomes: Nationwide Inpatient Sample (2007–2014). Journal Of Cardiac Failure 2020, 27: 258-260. PMID: 32505818, DOI: 10.1016/j.cardfail.2020.05.020.Peer-Reviewed Original ResearchPalliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database
Ando T, Adegbala O, Uemura T, Ashraf S, Akintoye E, Pahuja M, Afonso L, Briasoulis A, Takagi H. Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database. Angiology 2020, 71: 633-640. PMID: 32249588, DOI: 10.1177/0003319720917239.Peer-Reviewed Original ResearchConceptsLength of stayHospitalization costsPalliative careAortic aneurysmRepair groupNationwide Inpatient Sample databasePalliative care referralPC referral ratePercutaneous repair groupRuptured Aortic AneurysmSurgical repair groupNationwide Inpatient SamplePC referralCare referralInpatient SampleReferral ratesRetrospective analysisAdmissionStudy periodSample databaseFurther studiesStayAneurysmsReferralCare
2019
Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions
Subahi A, Osman M, Adegbala O, Abubakar H, Kheiri B, Yassin A, Khalid M, Akintoye E, Eljack A, Osman K, Alkhouli M. Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions. Vascular 2019, 28: 81-86. PMID: 31382836, DOI: 10.1177/1708538119868615.Peer-Reviewed Original ResearchConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryKidney injuryIschemic strokePulmonary embolismHigh riskDeep venous thrombosis/pulmonary embolismPercutaneous peripheral arterial interventionsICD-9-CM codesHospital mortality differenceProlonged hospital stayHospital-level characteristicsPeripheral arterial interventionsNational Inpatient SampleHospital outcomesHospital stayIntervention patientsAbsence of heparinBaseline characteristicsHome dischargeLonger hospitalizationArterial interventionsHospitalized patientsInpatient SampleThrombocytopeniaClinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestTrends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient SamplePredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shockImpact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort
Subahi A, Akintoye E, Yassin A, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L. Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort. Clinical Cardiology 2019, 42: 26-31. PMID: 30284301, PMCID: PMC6436524, DOI: 10.1002/clc.23088.Peer-Reviewed Original ResearchConceptsAtrial fibrillationHospital mortalityHospital outcomesAcute myocarditisICD-9-CM diagnostic codesNon-routine hospital dischargeImpact of AFPropensity score-matched control groupAcute myocarditis patientsAcute kidney injuryUnited States cohortNational Inpatient SampleCardiac tamponadeCardiogenic shockCause mortalityKidney injuryMyocarditis patientsAM patientsHospital dischargeAF groupInpatient SamplePrimary diagnosisDiagnostic codesHigh riskGeneral population
2018
Regional disparity in outcomes among patients hospitalized for Takotsubo cardiomyopathy in the United States✰
Adegbala O, Olagoke O, Adejumo A, Oluwole A, Akintoye E, Ando T, Tavares M, Williams K, Afonso L. Regional disparity in outcomes among patients hospitalized for Takotsubo cardiomyopathy in the United States✰. Heart & Lung 2018, 48: 79-84. PMID: 30446395, DOI: 10.1016/j.hrtlng.2018.10.024.Peer-Reviewed Original ResearchNational trends in Fontan operation and in-hospital outcomes in the USA
Akintoye E, Miranda W, Veldtman G, Connolly H, Egbe A. National trends in Fontan operation and in-hospital outcomes in the USA. Heart 2018, 105: 708. PMID: 30377261, DOI: 10.1136/heartjnl-2018-313680.Peer-Reviewed Original ResearchConceptsFontan operationHospital mortalityPostoperative complicationsClinical Modification procedure codesHypoplastic left heart syndromePostoperative cardiac complicationsCongenital heart disease diagnosisNationwide Inpatient SampleAcute care facilitiesLength of stayNumber of patientsDiseases-Ninth RevisionVolume of proceduresSignificant declineNumber of proceduresCardiac complicationsRespiratory complicationsHospital dischargeHospital outcomesPatient demographicsMedian ageHeart syndromeHospitalisation costsPatient populationSignificant changesEffect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Bhama J, Alvarez P. Effect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States. The Annals Of Thoracic Surgery 2018, 107: 527-532. PMID: 30316859, DOI: 10.1016/j.athoracsur.2018.08.051.Peer-Reviewed Original ResearchOutcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation
Yassin A, Subahi A, Abubakar H, Akintoye E, Alhusain R, Adegbala O, Ahmed A, Elmoughrabi A, Subahi E, Pahuja M, Sahlieh A, Elder M, Kaki A, Schreiber T, Mohamad T. Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 455-460. PMID: 30041889, DOI: 10.1016/j.amjcard.2018.04.013.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationLiver cirrhosisCirrhotic patientsValve implantationUnderwent Transcatheter Aortic Valve ImplantationNational Inpatient Sample databasePropensity score-matched analysisNonroutine hospital dischargeSevere aortic stenosisAortic valve replacementReasonable therapeutic optionCost of hospitalizationHospital mortalityHospital stayVascular complicationsHospital dischargeInpatient mortalitySecondary outcomesValve replacementAortic stenosisPacemaker implantationPrimary outcomeProcedural complicationsClinical outcomesClinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database)
Ando T, Akintoye E, Holmes A, Briasoulis A, Pahuja M, Takagi H, Schreiber T, Grines C, Afonso L. Clinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database). The American Journal Of Cardiology 2018, 122: 279-283. PMID: 29880287, DOI: 10.1016/j.amjcard.2018.03.356.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAortic ValveAortic Valve StenosisCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesYoung AdultConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationAortic valve replacementShorter hospital stayAortic valve implantationHospital mortalityHospital stayValve replacementValve implantationNational Inpatient Sample databaseSafe alternativeAcute kidney injuryOlder patient populationClinical end pointsAcute myocardial infarctionPropensity score analysisYears of agePostprocedure strokeKidney injuryValve surgeryVascular complicationsMajor complicationsPacemaker implantationPatient populationMyocardial infarctionIs Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis
Ando T, Adegbala O, Akintoye E, Ashraf S, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis. Journal Of The American Heart Association 2018, 7: e008408. PMID: 29606641, PMCID: PMC5907603, DOI: 10.1161/jaha.117.008408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCost SavingsCost-Benefit AnalysisDatabases, FactualFemaleHealth StatusHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCOPD patientsChronic obstructive pulmonary disease patientsAortic valve replacement resultsNationwide Inpatient Sample AnalysisSurgical aortic valve replacementObstructive pulmonary disease patientsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databaseRespiratory-related complicationsAcute kidney injuryAcute respiratory failurePropensity-matched cohortPulmonary disease patientsNoninvasive mechanical ventilationObstructive pulmonary diseaseAcute myocardial infarctionRespiratory related complicationsHospital mortalitySAVR patientsHospital stayKidney injuryRespiratory failure
2017
National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014)
Akintoye E, Briasoulis A, Egbe A, Dunlay S, Kushwaha S, Levine D, Afonso L, Mozaffarian D, Weinberger J. National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014). Journal Of The American Heart Association 2017, 6: e006955. PMID: 29187385, PMCID: PMC5779014, DOI: 10.1161/jaha.117.006955.Peer-Reviewed Original ResearchConceptsPrimary HF admissionsHospital mortality rateHF admissionsHospital mortalityMortality ratePrimary HF hospitalizationsIn-Hospital MortalityNational Inpatient SampleRate of admissionHospital mortality trendsAnnual national estimatesAnnual rateHF hospitalizationAverage annual rateHF guidelinesHeart failureSecondary diagnosisInpatient SampleHospitalization trendsAmerican CollegeAdmissionMortality trendsNational estimatesMortalityManagement guidelinesComparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients
Ando T, Akintoye E, Trehan N, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Comparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients. The American Journal Of Cardiology 2017, 120: 1858-1862. PMID: 28860018, DOI: 10.1016/j.amjcard.2017.07.098.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveAortic Valve StenosisBody Mass IndexComorbidityFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsMaleObesityPostoperative ComplicationsPrevalencePrognosisPropensity ScoreRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationSurgical aortic valve replacementAortic valve replacementTAVI patientsNonroutine dischargeObese patientsValve replacementTranscatheter Aortic Valve Implantation Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databaseHigher co-morbidity burdenCertain perioperative complicationsAcute kidney injuryIn-Hospital OutcomesShorter hospital stayAortic valve implantationCo-morbidity burdenMedian hospital costsAcute myocardial infarctionLength of stayCharlson scoreDeyo's modificationHospital mortalityCardiac complicationsHospital stayKidney injuryRegional Variation in Mortality, Length of Stay, Cost, and Discharge Disposition Among Patients Admitted for Heart Failure in the United States
Akintoye E, Briasoulis A, Egbe A, Adegbala O, Sheikh M, Singh M, Alliu S, Ahmed A, Asleh R, Kushwaha S, Levine D. Regional Variation in Mortality, Length of Stay, Cost, and Discharge Disposition Among Patients Admitted for Heart Failure in the United States. The American Journal Of Cardiology 2017, 120: 817-824. PMID: 28705376, DOI: 10.1016/j.amjcard.2017.05.058.Peer-Reviewed Original ResearchEffect of Hospital Ownership on Outcomes of Heart Failure Hospitalization
Akintoye E, Briasoulis A, Egbe A, Orhurhu V, Ibrahim W, Kumar K, Alliu S, Nas H, Levine D, Weinberger J. Effect of Hospital Ownership on Outcomes of Heart Failure Hospitalization. The American Journal Of Cardiology 2017, 120: 831-837. PMID: 28689752, DOI: 10.1016/j.amjcard.2017.06.009.Peer-Reviewed Original ResearchConceptsInpatient mortalityFemale patientsGovernment hospitalsHospitalization outcomesHospital ownershipSignificant differencesCharge of hospitalizationRoutine home dischargeHeart failure hospitalizationMean lengthNational Inpatient SampleCost of hospitalizationHF hospitalizationFailure hospitalizationHome dischargeHospital dischargeMale patientsInpatient SamplePrimary diagnosisProfit hospitalsHospitalizationMedian costMedian chargeMortality rateHospital