2022
Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation
Akintoye E, Salih M, Aje K, Alvarez P, Sellke F, Briasoulis A, Dorbala S. Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation. Canadian Journal Of Cardiology 2022, 38: 1263-1270. PMID: 35525397, DOI: 10.1016/j.cjca.2022.04.023.Peer-Reviewed Original ResearchConceptsHeart transplantGraft survivalAmyloid cardiomyopathyWaitlist mortalityHeart transplantationRisk factorsSingle-organ heart transplantsStudy periodHeart transplant waitlistUnderwent heart transplantWorse graft survivalGraft survival ratesOutcomes of patientsPropensity-matched cohortOrgan Sharing databaseHigher waitlist mortalityNumber of patientsNumber of transplantsAmyloid recurrenceAdult patientsGraft failureRenal failureIndependent predictorsSharing databaseUnited NetworkTrends In Waitlist And Post-transplant Outcomes After Heart Transplantation In The United States: Analysis OfUNOS Database 1991-2019
Akintoye E, Alvarez P, Shin D, Panos A, Briasoulis A. Trends In Waitlist And Post-transplant Outcomes After Heart Transplantation In The United States: Analysis OfUNOS Database 1991-2019. Journal Of Cardiac Failure 2022, 28: s61-s62. DOI: 10.1016/j.cardfail.2022.03.157.Peer-Reviewed Original ResearchPost-transplant outcomesHeart transplantationWaitlist mortalityPatient characteristicsAdult heart transplant recipientsHeart transplant recipientsHigh-risk comorbiditiesShort-term survivalHospital strokeHospital lengthTransplant recipientsRenal failureWaitlist deathsPatient selectionUnited NetworkPatient outcomesTransplant volumeSurgical techniqueEra 1Organ SharingEra 4PatientsNational databaseStudy periodTime points
2021
Changing Demographics, Temporal Trends in Waitlist, and Posttransplant Outcomes After Heart Transplantation in the United States: Analysis of the UNOS Database 1991–2019
Akintoye E, Alvarez P, Shin D, Egbe A, Panos A, Sellke F, Briasoulis A. Changing Demographics, Temporal Trends in Waitlist, and Posttransplant Outcomes After Heart Transplantation in the United States: Analysis of the UNOS Database 1991–2019. Circulation Heart Failure 2021, 14: e008764. PMID: 34689572, DOI: 10.1161/circheartfailure.121.008764.Peer-Reviewed Original ResearchConceptsHeart transplantationPosttransplant outcomesPatient characteristicsHigh-risk comorbiditiesCharacteristics of patientsShort-term survivalRisk comorbiditiesHospital strokeWaitlist mortalityRenal failureUnited NetworkTransplant volumeEra 1Organ SharingPatientsTransplantationWaitlistEra 4Study periodTime pointsSignificant decreaseTemporal trendsOutcomesSignificant changesUnited StatesShort and long term outcomes of cardiac amyloidosis patients listed for heart transplantation in the united states: a propensity-matched analysis
Akintoye E, Alvarez P, Briasoulis A. Short and long term outcomes of cardiac amyloidosis patients listed for heart transplantation in the united states: a propensity-matched analysis. European Heart Journal 2021, 42: ehab724.0965. DOI: 10.1093/eurheartj/ehab724.0965.Peer-Reviewed Original ResearchPost-transplant graft survivalGraft survivalGraft survival ratesPropensity-matched analysisCA patientsHigher waitlist mortalityHeart transplantationCardiac amyloidosis patientsWaitlist mortalityRestrictive cardiomyopathyRisk factorsDonor heartsAmyloidosis patientsSurvival rateStudy periodComparable graft survivalPoor graft survivalPropensity-matched cohortOrgan Sharing databaseSingle-center experienceCohort of patientsPredictors of survivalLong-term outcomesSignificant risk factorsAmyloid recurrenceChanging demographics, temporal trend in waitlist and post-transplant outcomes after heart transplantation in the United States: analysis of unos database 1991–2019
Akintoye E, Alvarez P, Shin D, Egbe A, Panos A, Briasoulis A. Changing demographics, temporal trend in waitlist and post-transplant outcomes after heart transplantation in the United States: analysis of unos database 1991–2019. European Heart Journal 2021, 42: ehab724.0953. DOI: 10.1093/eurheartj/ehab724.0953.Peer-Reviewed Original ResearchPost-transplant outcomesHeart transplantationWaitlist mortalityPatient characteristicsAdult heart transplant recipientsHeart transplant recipientsHigh-risk comorbiditiesCharacteristics of patientsShort-term survivalHospital strokeHospital lengthTransplant recipientsRenal failureWaitlist deathsPatient selectionUnited NetworkPatient outcomesTransplant volumeSurgical techniqueEra 1Organ SharingPatientsEra 4National databaseStudy period
2020
State-Level Variation in Waitlist Mortality and Transplant Outcomes Among Patients Listed for Heart Transplantation in the US From 2011 to 2016
Akintoye E, Shin D, Alvarez P, Briasoulis A. State-Level Variation in Waitlist Mortality and Transplant Outcomes Among Patients Listed for Heart Transplantation in the US From 2011 to 2016. JAMA Network Open 2020, 3: e2028459. PMID: 33295970, PMCID: PMC7726636, DOI: 10.1001/jamanetworkopen.2020.28459.Peer-Reviewed Original ResearchConceptsHeart transplantationGraft survivalWaitlist mortalityStatus 1AAdult patientsTransplant ratesSignificant state-level variationNationwide retrospective cohort studyAdult heart transplantationOutcomes of patientsRetrospective cohort studyMultivariable-adjusted modelsOrgan Sharing databaseRate of transplantRate of deathState-level variationRisk-adjustment modelsTransplant outcomesCohort studySharing databaseMedian timeScientific RegistryUnited NetworkLowest quartileOutcome measuresTrends in Adult Heart Transplantation and Associated Outcomes- Analysis of the Unos Registry
Akintoye E, Alvarez P, Briasoulis A. Trends in Adult Heart Transplantation and Associated Outcomes- Analysis of the Unos Registry. Journal Of Cardiac Failure 2020, 26: s83-s84. DOI: 10.1016/j.cardfail.2020.09.244.Peer-Reviewed Original ResearchAdult heart transplantationProcedure-related strokeHeart transplantationRenal failureHospital dischargePacemaker implantationStudy periodAdult donor heartsRate of strokePost-transplant survivalLength of hospitalizationPermanent pacemaker implantationHospitalization stayMedian hospitalizationGraft survivalSecondary outcomesPrimary outcomeDonor heartsUnited NetworkOutcome analysisOrgan SharingSurvival trendsOutcome trendsTransplantationSurvival endpointsCharacteristics and Outcomes of Patients Undergoing Combined Organ Transplantation (from the United Network for Organ Sharing)
Briasoulis A, Akintoye E, Kuno T, Alvarez P. Characteristics and Outcomes of Patients Undergoing Combined Organ Transplantation (from the United Network for Organ Sharing). The American Journal Of Cardiology 2020, 129: 42-45. PMID: 32540168, DOI: 10.1016/j.amjcard.2020.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack or African AmericanCardiomyopathy, DilatedCardiomyopathy, RestrictiveFemaleGraft RejectionHeart Defects, CongenitalHeart FailureHeart TransplantationHeart-Lung TransplantationHispanic or LatinoHumansKidney DiseasesKidney TransplantationLiver DiseasesLiver TransplantationLung DiseasesMaleMiddle AgedMortalityProportional Hazards ModelsRegistriesReoperationSurvival RateWhite PeopleConceptsHeart-liver transplantPrimary heart transplantationLong-term survivalHeart transplantationOrgan transplantsStage D heart failureD heart failureOutcomes of patientsOrgan Sharing registryLong-term outcomesCongenital heart diseaseAdult patientsMedian survivalHeart failureTransplantation ratesUnited NetworkList timeHeart diseaseOperative characteristicsOrgan transplantationSurvival analysisPatientsTransplantInverse probabilityStudy periodTemporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation
Briasoulis A, Adegbala O, Akintoye E, Alvarez P. Temporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation. Clinical Transplantation 2020, 34: e13857. PMID: 32167606, DOI: 10.1111/ctr.13857.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceRight ventricular assist deviceVentricular assist deviceOutcomes of patientsTime of listingTime of transplantationHeart transplantationAssist deviceOrgan Sharing registryTerms of survivalStatus 1AInotropic therapyLVAD recipientsUnited NetworkWorse outcomesInotropesHigh riskWaiting listPatientsTransplantationLower ratesOutcomesTemporal trendsConfoundersRegistryTemporal Trends and Outcomes of Patients Undergoing Combined Organ Transplantation: Insights from the United Network for Organ Sharing (UNOS)
Briasoulis A, Akintoye E, Alvarez P. Temporal Trends and Outcomes of Patients Undergoing Combined Organ Transplantation: Insights from the United Network for Organ Sharing (UNOS). The Journal Of Heart And Lung Transplantation 2020, 39: s167-s168. DOI: 10.1016/j.healun.2020.01.1126.Peer-Reviewed Original ResearchHeart-liver transplantPrimary heart transplantationLong-term survivalHeart transplantationUnited NetworkOrgan transplantsStage D heart failureD heart failureMethods Adult patientsOutcomes of patientsOrgan Sharing registryLong-term outcomesCongenital heart diseaseAdult patientsMedian survivalHeart failureTransplantation ratesList timeHeart diseaseOperative characteristicsOrgan transplantationOrgan SharingSurvival analysisPatientsTransplant
2019
Temporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant
Akintoye E, Briasoulis A, Duque E, Inampudi C, Bhama J, Alvarez P. Temporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant. The Journal Of Heart And Lung Transplantation 2019, 38: s347. DOI: 10.1016/j.healun.2019.01.880.Peer-Reviewed Original ResearchLeft ventricular assist deviceOutcomes of patientsTime of listingSub-hazard ratiosVentricular assist deviceInotropic therapyHeart transplantationAssist deviceHigher mean pulmonary arterial pressureMean pulmonary arterial pressureHigh wedge pressurePrior cardiac surgeryOrgan Sharing registryPulmonary arterial pressureTime of transplantNew allocation systemTerms of survivalWedge pressureLVAD patientsMethods PatientsArterial pressureCardiac surgeryHeart transplantPrimary outcomeLVAD supportTrends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015)
Briasoulis A, Akintoye E, Mohsen A, Inampudi C, Briasouli A, Asleh R, Alvarez P. Trends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015). Hellenic Journal Of Cardiology 2019, 61: 407-412. PMID: 30790715, DOI: 10.1016/j.hjc.2019.02.002.Peer-Reviewed Original ResearchConceptsLength of stayTotal artificial heartHospital mortalityHeart transplantationTAH implantationMajor complicationsLeft ventricular assist device implantationVentricular assist device implantationTotal artificial heart implantationComplex congenital heart diseaseStudy periodAcute kidney injuryAssist device implantationSame hospital staySevere biventricular failureDisposition of patientsNational Inpatient SampleTime of dischargeContinuous-flow LVADCost of hospitalizationArtificial heart implantationCongenital heart diseaseHospital complicationsMajor bleedingBiventricular failure
2017
Role of Doppler echocardiography for cardiac output assessment in Fontan patients
Egbe A, Khan A, Khan S, Anavekar N, Said S, Young P, Akintoye E, Miranda W, Al-Otaibi M, Veldtman G, Connolly H. Role of Doppler echocardiography for cardiac output assessment in Fontan patients. American Heart Journal 2017, 195: 91-98. PMID: 29224651, DOI: 10.1016/j.ahj.2017.09.014.Peer-Reviewed Original ResearchConceptsStroke volume indexSystemic left ventricleSystemic right ventricleFontan failureRight ventricleLeft ventricleFontan patientsTransthoracic echocardiographyLV patientsProtein-losing enteropathyCardiac output assessmentAge 17 yearsMean age 17 yearsHeart transplantationCardiac thrombusFontan conversionEjection fractionHeart failureDoppler echocardiographyPatientsVolume indexCMRIML/CirrhosisEchocardiography