2023
Prognostic Utility of Left Atrial Strain to Predict Thrombotic Events and Mortality in Amyloid Cardiomyopathy
Akintoye E, Majid M, Klein A, Hanna M. Prognostic Utility of Left Atrial Strain to Predict Thrombotic Events and Mortality in Amyloid Cardiomyopathy. JACC Cardiovascular Imaging 2023, 16: 1371-1383. PMID: 37940322, DOI: 10.1016/j.jcmg.2023.01.015.Peer-Reviewed Original ResearchConceptsThrombotic eventsAmyloid cardiomyopathyAtrial fibrillationLA contractileLA strainLA contractile strainModest discriminatory abilityPrognostic staging systemRisk stratification toolLeft Atrial StrainHigh thrombotic riskAtrial strainPrognostic utilityStratification toolPrognostic valueC-statisticRespective HRsStaging systemThrombotic riskACM patientsSD decreaseAF casesPredictive valuePatientsDiscriminatory abilityTEMPORALITY OF ISCHEMIC STROKE AND NEW-ONSET ATRIAL FIBRILLATION AND THE UTILITY OF LEFT ATRIAL STRAIN IN PATIENTS WITH CARDIAC AMYLOIDOSIS
Akintoye E, Majid M, Hanna M, Klein A. TEMPORALITY OF ISCHEMIC STROKE AND NEW-ONSET ATRIAL FIBRILLATION AND THE UTILITY OF LEFT ATRIAL STRAIN IN PATIENTS WITH CARDIAC AMYLOIDOSIS. Journal Of The American College Of Cardiology 2023, 81: 340. DOI: 10.1016/s0735-1097(23)00784-2.Peer-Reviewed Original Research
2022
Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation
Layoun H, Mentias A, Akintoye E, Matta M, Kanaan C, Daou R, Ramchand J, Burns D, Gillinov A, Bhattacharya S, Puri R, Collier P, Griffin B, Kapadia S, Harb S. Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation. Open Heart 2022, 9: e001996. PMID: 35383126, PMCID: PMC8984044, DOI: 10.1136/openhrt-2022-001996.Peer-Reviewed Original ResearchConceptsSecondary mitral regurgitationAtrial dilationMitral regurgitationPrognostic implicationsSevere left atrial dilationSevere secondary mitral regurgitationLA reservoir strainLeft atrial dilationLeft ventricle dysfunctionPoor prognostic indicatorMV interventionVentricle dysfunctionMore diabetesAdult patientsTransthoracic echocardiographyEjection fractionIndependent predictorsAtrial fibrillationReservoir strainWorse prognosisPrognostic indicatorMR severityBetter outcomesFunctional alterationsPatients
2019
Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestImpact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort
Subahi A, Akintoye E, Yassin A, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L. Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort. Clinical Cardiology 2019, 42: 26-31. PMID: 30284301, PMCID: PMC6436524, DOI: 10.1002/clc.23088.Peer-Reviewed Original ResearchConceptsAtrial fibrillationHospital mortalityHospital outcomesAcute myocarditisICD-9-CM diagnostic codesNon-routine hospital dischargeImpact of AFPropensity score-matched control groupAcute myocarditis patientsAcute kidney injuryUnited States cohortNational Inpatient SampleCardiac tamponadeCardiogenic shockCause mortalityKidney injuryMyocarditis patientsAM patientsHospital dischargeAF groupInpatient SamplePrimary diagnosisDiagnostic codesHigh riskGeneral population
2018
The impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis
Subahi A, Munir A, Abubakar H, Akintoye E, Yassin A, Adegbala O, Alraies M, Elder M, Mohamad T, Kaki A, Schreiber T. The impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis. Journal Of Interventional Cardiology 2018, 31: 925-931. PMID: 30456770, DOI: 10.1111/joic.12568.Peer-Reviewed Original ResearchConceptsTranscatheter mitral valve repairAtrial fibrillationHospital outcomesTranscatheter Mitral Valve Repair OutcomesICD-9-CM diagnostic codesMitral valve repair outcomesNational Inpatient Sample registryNon-routine hospital dischargeImpact of AFPrevalence of AFPropensity score-matched analysisHigher AF burdenPropensity-matched analysisRepresentative United States sampleHospital-level characteristicsMitral valve repairCost of hospitalizationLength of stayHospital mortalityAF burdenHospital dischargePatient characteristicsAF patientsBaseline rhythmTMVR proceduresPredictors, Burden, and the Impact of Arrhythmia on Patients Admitted for Acute Myocarditis
Adegbala O, Olagoke O, Akintoye E, Adejumo A, Oluwole A, Jara C, Williams K, Briasoulis A, Afonso L. Predictors, Burden, and the Impact of Arrhythmia on Patients Admitted for Acute Myocarditis. The American Journal Of Cardiology 2018, 123: 139-144. PMID: 30539745, DOI: 10.1016/j.amjcard.2018.09.017.Peer-Reviewed Original ResearchConceptsImpact of arrhythmiasCardiac arrhythmiasAcute myocarditisNonroutine hospital dischargePredictors of arrhythmiasPropensity-matched analysisMechanical circulatory supportSudden cardiac deathOccurrence of arrhythmiasCost of hospitalizationLength of staySignificant proportionHospital mortalityCardiogenic shockHospital outcomesHospital dischargeMyocarditis casesCardiac deathIndependent predictorsPacemaker implantationAtrial fibrillationCirculatory supportCommon arrhythmiaVentricular tachycardiaWorse outcomesSafety and Efficacy of Novel Oral Anticoagulants Versus Warfarin in Medicare Beneficiaries With Atrial Fibrillation and Valvular Heart Disease
Briasoulis A, Inampudi C, Akintoye E, Alvarez P, Panaich S, Vaughan‐Sarrazin M. Safety and Efficacy of Novel Oral Anticoagulants Versus Warfarin in Medicare Beneficiaries With Atrial Fibrillation and Valvular Heart Disease. Journal Of The American Heart Association 2018, 7: e008773. PMID: 29622591, PMCID: PMC6015407, DOI: 10.1161/jaha.118.008773.Peer-Reviewed Original ResearchConceptsValvular heart diseaseAtrial fibrillationMedicare beneficiariesIschemic strokeHeart diseaseNew-onset atrial fibrillationNon-vitamin K anticoagulantsGastrointestinal bleeding ratesLarge community-based samplePropensity-matched sampleCommunity-based sampleMajor bleedingNongastrointestinal bleedingCause mortalitySystemic thromboembolismVersus WarfarinPrimary outcomePropensity matchingMyocardial infarctionBleeding rateLower riskPatientsRivaroxabanWarfarinDabigatranRelation of Cannabis Use and Atrial Fibrillation Among Patients Hospitalized for Heart Failure
Adegbala O, Adejumo A, Olakanmi O, Akinjero A, Akintoye E, Alliu S, Edo-Osagie E, Chatterjee A. Relation of Cannabis Use and Atrial Fibrillation Among Patients Hospitalized for Heart Failure. The American Journal Of Cardiology 2018, 122: 129-134. PMID: 29685570, DOI: 10.1016/j.amjcard.2018.03.015.Peer-Reviewed Original ResearchConceptsDiagnosis of HFAtrial fibrillationHeart failureNervous systemCannabis usersOccurrence of AFUtilization Project National Inpatient SampleDiagnosis of AFCannabis useLeft ventricular dysfunctionCo-morbid conditionsSympathetic nervous systemCannabis user groupAutonomic nervous systemInotropic supportVentricular dysfunctionCardiovascular effectsSympathetic effectsSympathetic activityAutonomic effectsInpatient SampleAF diagnosisInsurance typeMain exposureLower oddsFinancial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
Abubakar H, Yassin A, Akintoye E, Bakhit K, Pahuja M, Shokr M, Lieberman R, Afonso L. Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database). The American Journal Of Cardiology 2018, 121: 1587-1592. PMID: 29622287, DOI: 10.1016/j.amjcard.2018.02.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisArrhythmias, CardiacAtrial FibrillationCardiac Pacing, ArtificialCardiac TamponadeComorbidityDatabases, FactualFemaleHeart ArrestHeart FailureHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMyocardial InfarctionPacemaker, ArtificialPericardial EffusionPostoperative ComplicationsPostoperative HemorrhageStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationPre-existing atrial fibrillationLength of stayPeriprocedural cardiac complicationsAortic valve implantationAtrial fibrillationCost of hospitalizationCardiac complicationsHospital mortalityEnd pointValve implantationLonger hospital LOSUnderwent Transcatheter Aortic Valve ImplantationPre-existing AFHospital LOSIncidence of AFLonger LOSNationwide Inpatient Sample databaseIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsMixed-effects logistic modelTAVI patients
2017
Factors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery
Akintoye E, Sellke F, Marchioli R, Tavazzi L, Mozaffarian D. Factors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 242-251.e10. PMID: 28890081, DOI: 10.1016/j.jtcvs.2017.07.063.Peer-Reviewed Original ResearchConceptsPostoperative atrial fibrillationMajor adverse cardiovascular eventsCoronary artery bypassAdverse cardiovascular eventsArtery bypassAtrial fibrillationCardiovascular eventsCardiac surgeryHigh riskConcomitant valvularValvular surgeryCardiopulmonary bypassAdverse outcomesVentricular pacingBypass useCoronary artery bypass graft surgeryConcomitant coronary artery bypassArtery bypass graft surgeryBypass graft surgeryMultivariable-adjusted modelsCardiopulmonary bypass useType of surgeryData of patientsSpecific adverse outcomesSurgery characteristics