2024
Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
Matta K, Viallon V, Botteri E, Peveri G, Dahm C, Nannsen A, Olsen A, Tjønneland A, Elbaz A, Artaud F, Marques C, Kaaks R, Katzke V, Schulze M, Llanaj E, Masala G, Pala V, Panico S, Tumino R, Ricceri F, Derksen J, Nøst T, Sandanger T, Borch K, Quirós J, Castro-Espin C, Sánchez M, Atxega A, Cirera L, Guevara M, Manjer J, Tin Tin S, Heath A, Touvier M, Goldberg M, Weiderpass E, Gunter M, Freisling H, Riboli E, Ferrari P. Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort. BMC Medicine 2024, 22: 210. PMID: 38807179, PMCID: PMC11134634, DOI: 10.1186/s12916-024-03362-7.Peer-Reviewed Original ResearchConceptsHealthy lifestyle indexAssociated with all-causeHealthy lifestyle changesEuropean Prospective InvestigationRisk of deathCancer mortalityFollow-up questionnaireAll-causeLifestyle changesProspective InvestigationRate advancement periodsUnhealthy lifestyle changesRisk of noncommunicable diseasesCancer and NutritionCancer-free adultsBody mass indexBackgroundHealthy lifestylesLifestyle behaviorsNutrition CohortLifestyle indexLifestyle ProfilePhysical activityAssociated with mortalityNoncommunicable diseasesChange scoresOccupation and tongue cancer in Nordic countries
Peltonen J, Nikkilä R, Al-Samadi A, Mäkitie A, Martinsen J, Kjaerheim K, Lynge E, Sparen P, Tryggvadottir L, Weiderpass E, Salo T, Pukkala E. Occupation and tongue cancer in Nordic countries. BMC Oral Health 2024, 24: 506. PMID: 38685000, PMCID: PMC11059716, DOI: 10.1186/s12903-024-04172-2.Peer-Reviewed Original ResearchConceptsStandardized incidence ratioNordic Occupational CancerNational incidence ratesTongue cancerBeverage workersConsumption of alcoholEffects of carcinogen exposureSignificant SIRsIncidence ratiosResultsAmong menInactive personsOccupational cancerIncidence rateNordic countriesOccupational categoriesMethodsThe dataArtistic workersRisk variationMale farmersConclusionsThese findingsCarcinogen exposureWorkersForestry workersCancerTobaccoDietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study
Zheng J, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw Y, Tong T, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm C, Heath A, Ibsen D, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze M, Sieri S, Wareham N, Danesh J, Butterworth A, Forouhi N. Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study. American Journal Of Clinical Nutrition 2024, 119: 1164-1174. PMID: 38479550, PMCID: PMC11130694, DOI: 10.1016/j.ajcnut.2024.03.006.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseDietary protein intakeProtein intakeCase-cohort studyCardiovascular diseaseIncident cardiovascular diseaseFatal strokeAssociated with lower incidenceIncidence of fatal strokeRisk of cardiovascular diseaseEuropean Prospective InvestigationPrentice-weighted Cox regressionAssociated with incident cardiovascular diseaseOverall CVDIncident CVD casesIntake of plantMacronutrient intakeStroke incidenceProtein consumptionSubcohort membersIsocaloric substitutionDietary patternsDietary intakeNever smokersProspective InvestigationBMI and breast cancer risk around age at menopause
Von Holle A, Adami H, Baglietto L, Berrington de Gonzalez A, Bertrand K, Blot W, Chen Y, DeHart J, Dossus L, Eliassen A, Fournier A, Garcia-Closas M, Giles G, Guevara M, Hankinson S, Heath A, Jones M, Joshu C, Kaaks R, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Masala G, Mellemkjaer L, Milne R, O'Brien K, Palmer J, Riboli E, Rohan T, Shrubsole M, Sund M, Tamimi R, Tin Tin S, Visvanathan K, Vermeulen R, Weiderpass E, Willett W, Yuan J, Zeleniuch-Jacquotte A, Nichols H, Sandler D, Swerdlow A, Schoemaker M, Weinberg C. BMI and breast cancer risk around age at menopause. Cancer Epidemiology 2024, 89: 102545. PMID: 38377945, PMCID: PMC10942753, DOI: 10.1016/j.canep.2024.102545.Peer-Reviewed Original ResearchConceptsBreast cancer riskCancer riskHazard ratioBreast cancer hazard ratioCancer hazard ratioFive-unit incrementNatural menopauseBreast cancer etiologyHigher body mass indexLoss to follow-upAssociated with decreased riskBreast cancer diagnosisMenopausal status groupsBody mass indexYears age rangeMenopausal hormone therapyPrimary time scalePerson-timeCancer etiologyLoss of ovarian functionCancer diagnosisMass indexBMIPositive associationStatus groupsFemale reproductive histories and the risk of chronic obstructive pulmonary disease
Liang C, Chung H, Dobson A, Sandin S, Weiderpass E, Mishra G. Female reproductive histories and the risk of chronic obstructive pulmonary disease. Thorax 2024, 79: 508-514. PMID: 38350732, DOI: 10.1136/thorax-2023-220388.Peer-Reviewed Original ResearchConceptsRisk of chronic obstructive pulmonary diseaseChronic obstructive pulmonary diseaseFemale reproductive factorsReproductive factorsObstructive pulmonary diseaseNatural menopauseBirth yearIncreased risk of COPDPulmonary diseaseBody mass indexDevelopment of chronic obstructive pulmonary diseaseEducation levelCox regression modelsMass indexReproductive historyIncreased riskCohort differencesStillbirthRegression modelsFemale reproductive historyMenarcheMedian follow-upWomenFemale hormonal environmentCohort
2023
Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses
Collaboration E, Sofianopoulou E, Kaptoge S, Afzal S, Jiang T, Gill D, Gundersen T, Bolton T, Allara E, Arnold M, Mason A, Chung R, Pennells L, Shi F, Sun L, Willeit P, Forouhi N, Langenberg C, Sharp S, Panico S, Engström G, Melander O, Tong T, Perez-Cornago A, Norberg M, Johansson I, Katzke V, Srour B, Sánchez M, Redondo-Sánchez D, Olsen A, Dahm C, Overvad K, Brustad M, Skeie G, Moreno-Iribas C, Onland-Moret N, van der Schouw Y, Tsilidis K, Heath A, Agnoli C, Krogh V, de Boer I, Kobylecki C, Çolak Y, Zittermann A, Sundström J, Welsh P, Weiderpass E, Aglago E, Ferrari P, Clarke R, Boutron M, Severi G, MacDonald C, Providencia R, Masala G, Zamora-Ros R, Boer J, Verschuren M, Cawthon P, Schierbeck L, Cooper C, Schulze M, Bergmann M, Hannemann A, Kiechl S, Brenner H, van Schoor N, Albertorio J, Sacerdote C, Linneberg A, Kårhus L, Huerta J, Imaz L, Joergensen C, Ben-Shlomo Y, Lundqvist A, Gallacher J, Sattar N, Wood A, Wareham N, Nordestgaard B, Di Angelantonio E, Danesh J, Butterworth A, Burgess S. Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. The Lancet Diabetes & Endocrinology 2023, 12: e2-e11. PMID: 38048800, PMCID: PMC7615586, DOI: 10.1016/s2213-8587(23)00287-5.Peer-Reviewed Original ResearchMeSH KeywordsCoronary DiseaseHumansMiddle AgedMyocardial InfarctionProspective StudiesStrokeVitamin DVitaminsConceptsMendelian randomisation analysisCoronary heart diseaseRandomisation analysesAll-cause mortalityMortality outcomesFatal ischaemic heart diseaseHeart diseaseIncident coronary heart diseaseHistory of coronary heart diseasePopulation-based cohort studyHealth Data Research UKCause-specific mortality outcomesNational Institute for Health ResearchMendelian randomisation frameworkDose-response relationshipIndividuals of European ancestryRisk of coronary heart diseaseRandomised trials of vitamin D supplementationLow vitamin D statusBritish Heart FoundationCancer Research UKInternational Agency for Research on CancerMiddle-aged individualsIschaemic heart diseaseMedical Research CouncilDietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries
Fiolet T, Nicolas G, Casagrande C, Horvath Z, Frenoy P, Weiderpass E, Gunter M, Manjer J, Sonestedt E, Palli D, Simeon V, Tumino R, Bueno-de-Mesquita B, Huerta J, Rodriguez-Barranco M, Abilleira E, Sacerdote C, Schulze M, Heath A, Rylander C, Skeie G, Nøst T, Tjønneland A, Olsen A, Pala V, Kvaskoff M, Huybrechts I, Mancini F. Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries. International Journal Of Hygiene And Environmental Health 2023, 255: 114287. PMID: 37989047, DOI: 10.1016/j.ijheh.2023.114287.Peer-Reviewed Original ResearchConceptsDietary intakeCause mortalityCohort studyIntake of dioxinsCancer mortalityGeneral populationEPIC cohort studyMultivariable Cox regressionEuropean Prospective InvestigationCardiovascular-specific mortalityMain exposure sourceNDL-PCBsFood consumption dataFood contamination dataSerum/plasmaNon-linear associationNutrition CohortCardiovascular mortalityHazard ratioCox regressionNon-monotonic dose responsesProspective InvestigationEuropean Food Safety AuthorityMortalityInconsistent associationsEthnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies.
Chung H, Dobson A, Hayashi K, Hardy R, Kuh D, Anderson D, van der Schouw Y, Greenwood D, Cade J, Demakakos P, Brunner E, Eastwood S, Sandin S, Weiderpass E, Mishra G. Ethnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies. Diabetes Care 2023, 46: 2024-2034. PMID: 37747341, PMCID: PMC10696407, DOI: 10.2337/dc23-1209.Peer-Reviewed Original ResearchConceptsIncreased risk of T2DPremature ovarian insufficiencyRisk of T2DType 2 diabetesPooled individual-level dataCohort studyHazard ratioIncident type 2 diabetesRisk of type 2 diabetesEthnic groupsNatural menopauseChinese womenEarly menopauseIncreased riskYears of follow-upIndividual-level dataBirth yearEducation levelInvestigate associationsRisk estimatesOvarian insufficiencyPostmenopausal womenEthnic differencesRisk factorsPooled analysisAge at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women
Tschiderer L, Peters S, van der Schouw Y, van Westing A, Tong T, Willeit P, Seekircher L, Moreno‐Iribas C, Huerta J, Crous‐Bou M, Söderholm M, Schulze M, Johansson C, Själander S, Heath A, Macciotta A, Dahm C, Ibsen D, Pala V, Mellemkjær L, Burgess S, Wood A, Kaaks R, Katzke V, Amiano P, Rodriguez‐Barranco M, Engström G, Weiderpass E, Tjønneland A, Halkjær J, Panico S, Danesh J, Butterworth A, Onland‐Moret N. Age at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women. Journal Of The American Heart Association 2023, 12: e030280. PMID: 37681566, PMCID: PMC10547274, DOI: 10.1161/jaha.123.030280.Peer-Reviewed Original ResearchConceptsMendelian randomization analysisRisk of strokeStatistically significant associationRandomization analysisSignificant associationHistory of strokeEPIC-CVDPooled mean ageHigh risk of strokeUK BiobankYears younger ageBaseline ageHazard ratioStroke subtypesObservational studyPooled hazard ratioHemorrhagic strokeEarly menopauseYounger ageMean ageHigh riskMedian follow-upStrokeRegression analysisWomen