Opium use and risk of colorectal cancer: a multi-center case-referent study in Iran
Hadji M, Marzban M, Rashidian H, Naghibzadeh-Tahami A, Gholipour M, Mohebbi E, Safari-Faramani R, Seyyedsalehi M, Hosseini B, Alizadeh-Navaei R, Rezaianzadeh A, Moradi A, ShahidSales S, Najafi F, Moazed V, Haghdoost A, Rahimi-Movaghar A, Etemadi A, Malekzadeh R, Boffetta P, Weiderpass E, Kamangar F, Zendehdel K, Pukkala E. Opium use and risk of colorectal cancer: a multi-center case-referent study in Iran. Acta Oncologica 2023, 62: 1661-1668. PMID: 37934078, DOI: 10.1080/0284186x.2023.2276326.Peer-Reviewed Original ResearchConceptsRisk of colorectal cancerCase-referent studyOpium useColorectal cancerIncreased risk of CRCOdds ratioMultivariable unconditional logistic regression modelOccupational physical activityUnconditional logistic regression modelsIncreased risk of cancerColorectal cancer casesIncreased riskConsumption of red meatMeasure odds ratiosRisk of cancerInternational Agency for Cancer ResearchLogistic regression modelsPhysical activityTrained interviewersSocioeconomic statusPotential confoundersMarital statusFamily historyRed meatOpium consumptionProspective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
Nimptsch K, Aleksandrova K, Pham T, Papadimitriou N, Janke J, Christakoudi S, Heath A, Olsen A, Tjønneland A, Schulze M, Katzke V, Kaaks R, van Guelpen B, Harbs J, Palli D, Macciotta A, Pasanisi F, Yohar S, Guevara M, Amiano P, Grioni S, Jakszyn P, Figueiredo J, Samadder N, Li C, Moreno V, Potter J, Schoen R, Um C, Weiderpass E, Jenab M, Gunter M, Pischon T. Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer. BMC Medicine 2023, 21: 391. PMID: 37833736, PMCID: PMC10576353, DOI: 10.1186/s12916-023-03104-1.Peer-Reviewed Original ResearchConceptsColorectal cancer riskColorectal cancer casesMendelian randomizationColorectal cancerEpidemiology of Colorectal Cancer ConsortiumAssociated with colorectal cancer riskTwo-sample Mendelian randomization studyColon Cancer Family RegistryPublished genome-wide association studiesColorectal Cancer ConsortiumCancer Family RegistryConditional logistic regression modelsMendelian randomization analysisMendelian randomization studiesCancer and NutritionEuropean Prospective InvestigationNested case-control studyGenome-wide association studiesLogistic regression modelsCase-control studyDevelopment of colorectal cancerFamily RegistryStatistically significant associationCancer ConsortiumCancer risk