Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis
O’Grady T, Rinaldi S, Michels K, Adami H, Buring J, Chen Y, Clendenen T, D’Aloisio A, DeHart J, Franceschi S, Freedman N, Gierach G, Giles G, Lacey J, Lee I, Liao L, Linet M, McCullough M, Patel A, Prizment A, Robien K, Sandler D, Stolzenberg-Solomon R, Weiderpass E, White E, Wolk A, Zheng W, de Gonzalez A, Kitahara C. Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis. International Journal Of Epidemiology 2023, 53: dyad172. PMID: 38110618, PMCID: PMC10859160, DOI: 10.1093/ije/dyad172.Peer-Reviewed Original ResearchConceptsThyroid cancer riskRisk of DTCDTC riskCancer riskMultivariable-adjusted Cox proportional hazards modelsMenopausal hormone therapy useHazard ratioFactors associated with higher riskEstimate hazard ratiosHormonal factorsOral contraceptivesHormone therapy useFactor associated with lower riskCox proportional hazards modelsProspective cohort analysisIncidence of differentiated thyroid cancerPost-menopausal statusMenopausal hormone therapyProportional hazards modelExposure misclassificationReproductive factorsPre-diagnosticTherapy useEvaluate associationsSex steroid hormonesInternational Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts
Timmins I, Jones M, O'Brien K, Adami H, Aune D, Baglietto L, Bertrand K, Brantley K, Chen Y, DeHart J, Clendenen T, Dossus L, Eliassen A, Fletcher O, Fournier A, Håkansson N, Hankinson S, Houlston R, Joshu C, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Lynch B, May A, Mellemkjær L, Milne R, Palmer J, Ricceri F, Rohan T, Ruddy K, Sánchez M, Shu X, Smith-Byrne K, Steindorf K, Sund M, Vachon C, Vatten L, Visvanathan K, Weiderpass E, Willett W, Wolk A, Yuan J, Zheng W, Nichols H, Sandler D, Swerdlow A, Schoemaker M. International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts. Journal Of Clinical Oncology 2023, 42: 927-939. PMID: 38079601, PMCID: PMC10927335, DOI: 10.1200/jco.23.01101.Peer-Reviewed Original ResearchLeisure-time physical activityLevels of leisure-time physical activityBreast cancer riskPremenopausal breast cancerBreast cancer risk factorsPhysical activityCancer risk factorsCancer riskHazard ratioHigher levels of leisure-time physical activityAssociations of leisure-time physical activityLow levels of leisure-time physical activitySelf-reported leisure-time physical activityIncident cases of breast cancerAssociation of physical activityPostmenopausal breast cancer riskPremenopausal breast cancer riskBreast cancerPooled analysis of cohort studiesPooled individual-level dataCohort studyAnalysis of cohort studiesBreast cancer incidenceCases of breast cancerEstimate hazard ratiosDietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries
Tong T, Clarke R, Schmidt J, Huybrechts I, Noor U, Forouhi N, Imamura F, Travis R, Weiderpass E, Aleksandrova K, Dahm C, van der Schouw Y, Overvad K, Kyrø C, Tjønneland A, Kaaks R, Katzke V, Schiborn C, Schulze M, Mayen-Chacon A, Masala G, Sieri S, de Magistris M, Tumino R, Sacerdote C, Boer J, Verschuren W, Brustad M, Nøst T, Crous-Bou M, Petrova D, Amiano P, Huerta J, Moreno-Iribas C, Engström G, Melander O, Johansson K, Lindvall K, Aglago E, Heath A, Butterworth A, Danesh J, Key T. Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries. European Journal Of Nutrition 2023, 63: 209-220. PMID: 37804448, PMCID: PMC10799144, DOI: 10.1007/s00394-023-03251-4.Peer-Reviewed Original ResearchConceptsRisk of ischaemic strokeHaemorrhagic strokeRisk of stroke subtypesMultivariable-adjusted Cox regression modelsHazard ratioIschaemic strokeStroke subtypesCountry-specific dietary questionnairesBlood pressureConfidence intervalsEstimate hazard ratiosProline intakeMethodsWe analysed dataMultiple testingStatistically significant associationDietary recallsDietary questionnaireInverse associationCox regression modelsDiastolic blood pressureEPIC studyHigher intakeDietary amino acidsDietary intakeMutual adjustment