International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts
Timmins I, Jones M, O'Brien K, Adami H, Aune D, Baglietto L, Bertrand K, Brantley K, Chen Y, DeHart J, Clendenen T, Dossus L, Eliassen A, Fletcher O, Fournier A, Håkansson N, Hankinson S, Houlston R, Joshu C, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Lynch B, May A, Mellemkjær L, Milne R, Palmer J, Ricceri F, Rohan T, Ruddy K, Sánchez M, Shu X, Smith-Byrne K, Steindorf K, Sund M, Vachon C, Vatten L, Visvanathan K, Weiderpass E, Willett W, Wolk A, Yuan J, Zheng W, Nichols H, Sandler D, Swerdlow A, Schoemaker M. International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts. Journal Of Clinical Oncology 2023, 42: 927-939. PMID: 38079601, PMCID: PMC10927335, DOI: 10.1200/jco.23.01101.Peer-Reviewed Original ResearchLeisure-time physical activityLevels of leisure-time physical activityBreast cancer riskPremenopausal breast cancerBreast cancer risk factorsPhysical activityCancer risk factorsCancer riskHazard ratioHigher levels of leisure-time physical activityAssociations of leisure-time physical activityLow levels of leisure-time physical activitySelf-reported leisure-time physical activityIncident cases of breast cancerAssociation of physical activityPostmenopausal breast cancer riskPremenopausal breast cancer riskBreast cancerPooled analysis of cohort studiesPooled individual-level dataCohort studyAnalysis of cohort studiesBreast cancer incidenceCases of breast cancerEstimate hazard ratiosDietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries
Fiolet T, Nicolas G, Casagrande C, Horvath Z, Frenoy P, Weiderpass E, Gunter M, Manjer J, Sonestedt E, Palli D, Simeon V, Tumino R, Bueno-de-Mesquita B, Huerta J, Rodriguez-Barranco M, Abilleira E, Sacerdote C, Schulze M, Heath A, Rylander C, Skeie G, Nøst T, Tjønneland A, Olsen A, Pala V, Kvaskoff M, Huybrechts I, Mancini F. Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries. International Journal Of Hygiene And Environmental Health 2023, 255: 114287. PMID: 37989047, DOI: 10.1016/j.ijheh.2023.114287.Peer-Reviewed Original ResearchConceptsDietary intakeCause mortalityCohort studyIntake of dioxinsCancer mortalityGeneral populationEPIC cohort studyMultivariable Cox regressionEuropean Prospective InvestigationCardiovascular-specific mortalityMain exposure sourceNDL-PCBsFood consumption dataFood contamination dataSerum/plasmaNon-linear associationNutrition CohortCardiovascular mortalityHazard ratioCox regressionNon-monotonic dose responsesProspective InvestigationEuropean Food Safety AuthorityMortalityInconsistent associationsEthnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies.
Chung H, Dobson A, Hayashi K, Hardy R, Kuh D, Anderson D, van der Schouw Y, Greenwood D, Cade J, Demakakos P, Brunner E, Eastwood S, Sandin S, Weiderpass E, Mishra G. Ethnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies. Diabetes Care 2023, 46: 2024-2034. PMID: 37747341, PMCID: PMC10696407, DOI: 10.2337/dc23-1209.Peer-Reviewed Original ResearchConceptsIncreased risk of T2DPremature ovarian insufficiencyRisk of T2DType 2 diabetesPooled individual-level dataCohort studyHazard ratioIncident type 2 diabetesRisk of type 2 diabetesEthnic groupsNatural menopauseChinese womenEarly menopauseIncreased riskYears of follow-upIndividual-level dataBirth yearEducation levelInvestigate associationsRisk estimatesOvarian insufficiencyPostmenopausal womenEthnic differencesRisk factorsPooled analysis