2024
Pre‐diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: Results from the European Prospective Investigation into Cancer and Nutrition study
Pham T, Nimptsch K, Aleksandrova K, Jenab M, Fedirko V, Wu K, Eriksen A, Tjønneland A, Severi G, Rothwell J, Kaaks R, Katzke V, Catalano A, Agnoli C, Masala G, De Magistris M, Tumino R, Vermeulen R, Aizpurua A, Trobajo‐Sanmartín C, Chirlaque M, Sánchez M, San Moon Lu S, Cross A, Christakoudi S, Weiderpass E, Pischon T. Pre‐diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: Results from the European Prospective Investigation into Cancer and Nutrition study. International Journal Of Cancer 2024, 154: 1596-1606. PMID: 38200695, DOI: 10.1002/ijc.34830.Peer-Reviewed Original ResearchColorectal cancer diagnosisCRC-specific mortalityEuropean Prospective InvestigationAll-cause mortalityCox proportional hazards modelsProportional hazards modelColorectal cancerCRC-specificAssociated with CRC-specific mortalityPre-diagnosticResistin concentrationsProspective InvestigationHazards modelHazard ratioIncident CRC casesFine-Gray proportional subdistribution hazards modelCause-specific Cox proportional hazards modelsSubgroup analysisBody mass indexNutrition CohortProportional subdistribution hazards modelMedian follow-upAssociated with increased mortalitySubdistribution hazard modelCRC cases
2023
Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses
Collaboration E, Sofianopoulou E, Kaptoge S, Afzal S, Jiang T, Gill D, Gundersen T, Bolton T, Allara E, Arnold M, Mason A, Chung R, Pennells L, Shi F, Sun L, Willeit P, Forouhi N, Langenberg C, Sharp S, Panico S, Engström G, Melander O, Tong T, Perez-Cornago A, Norberg M, Johansson I, Katzke V, Srour B, Sánchez M, Redondo-Sánchez D, Olsen A, Dahm C, Overvad K, Brustad M, Skeie G, Moreno-Iribas C, Onland-Moret N, van der Schouw Y, Tsilidis K, Heath A, Agnoli C, Krogh V, de Boer I, Kobylecki C, Çolak Y, Zittermann A, Sundström J, Welsh P, Weiderpass E, Aglago E, Ferrari P, Clarke R, Boutron M, Severi G, MacDonald C, Providencia R, Masala G, Zamora-Ros R, Boer J, Verschuren M, Cawthon P, Schierbeck L, Cooper C, Schulze M, Bergmann M, Hannemann A, Kiechl S, Brenner H, van Schoor N, Albertorio J, Sacerdote C, Linneberg A, Kårhus L, Huerta J, Imaz L, Joergensen C, Ben-Shlomo Y, Lundqvist A, Gallacher J, Sattar N, Wood A, Wareham N, Nordestgaard B, Di Angelantonio E, Danesh J, Butterworth A, Burgess S. Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. The Lancet Diabetes & Endocrinology 2023, 12: e2-e11. PMID: 38048800, PMCID: PMC7615586, DOI: 10.1016/s2213-8587(23)00287-5.Peer-Reviewed Original ResearchConceptsMendelian randomisation analysisCoronary heart diseaseRandomisation analysesAll-cause mortalityMortality outcomesFatal ischaemic heart diseaseHeart diseaseIncident coronary heart diseaseHistory of coronary heart diseasePopulation-based cohort studyHealth Data Research UKCause-specific mortality outcomesNational Institute for Health ResearchMendelian randomisation frameworkDose-response relationshipIndividuals of European ancestryRisk of coronary heart diseaseRandomised trials of vitamin D supplementationLow vitamin D statusBritish Heart FoundationCancer Research UKInternational Agency for Research on CancerMiddle-aged individualsIschaemic heart diseaseMedical Research Council