2023
Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program
Murphy M, Edemobi P, Leasure A, Gulati M, Miller E, Damsky W, Cohen J. Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program. Rheumatology Advances In Practice 2023, 7: rkad030. PMID: 38606002, PMCID: PMC11007907, DOI: 10.1093/rap/rkad030.Peer-Reviewed Original ResearchCase-control studyAutoimmune diseasesSarcoidosis patientsMultivariable analysisOdds ratioSarcoidosis casesUs Research ProgramDiverse cohortConcomitant autoimmune diseasesRace-matched controlsMultiple autoimmune diseasesAutoimmune comorbiditiesSarcoidosisPatientsLogistic regressionDiseaseSmall sample sizeCareful screeningCohortAssociationSample sizeComposite variablePrior studiesComorbiditiesStudyNovel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers
Shi T, Miller E. Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers. Current Cardiovascular Imaging Reports 2023, 16: 1-9. PMID: 36926261, PMCID: PMC9996562, DOI: 10.1007/s12410-023-09574-4.Peer-Reviewed Original ResearchCardiac sarcoidosisMyocardial inflammatory diseaseDisease activityImmunomodulatory therapyInflammatory cardiomyopathyMyocardial inflammationInflammatory diseasesPrognostic performanceReviewThe purposeNovel radiotracersMyocarditisSarcoidosisTherapy guidanceInflammationMolecular featuresRadiotracerClinical translationMolecular imagingMolecular mechanismsHigh specificityCardiomyopathyImproved mechanistic insightsPathogenesisTherapyDisease
2021
Potential novel imaging targets of inflammation in cardiac sarcoidosis
Park J, Young BD, Miller EJ. Potential novel imaging targets of inflammation in cardiac sarcoidosis. Journal Of Nuclear Cardiology 2021, 29: 2171-2187. PMID: 34734365, DOI: 10.1007/s12350-021-02838-w.Peer-Reviewed Original ResearchConceptsCardiac sarcoidosisFDG-PET imagingPositron emission tomographyF-fluorodeoxyglucose positron emission tomographyNon-caseating granulomatous inflammationGranulomatous inflammationHigh morbiditySarcoid granulomasInflammatory diseasesPathognomonic featuresInflammationEmission tomographySarcoidosisMolecular targetsImaging targetsImagingMorbidityGranulomasMortalityDisease
2020
Treatment of Multiorgan Sarcoidosis With Tofacitinib
Damsky W, Young BD, Sloan B, Miller EJ, Obando JA, King B. Treatment of Multiorgan Sarcoidosis With Tofacitinib. ACR Open Rheumatology 2020, 2: 106-109. PMID: 31916703, PMCID: PMC7011417, DOI: 10.1002/acr2.11112.Peer-Reviewed Original ResearchMultiorgan sarcoidosisTumor necrosis factor α blockadeNecrosis factor α blockadeCutaneous sarcoidosis lesionsEfficacy of tofacitinibIdiopathic inflammatory disorderJanus kinase inhibitorRecalcitrant sarcoidosisΑ-blockadeClinical remissionSarcoidosis lesionsGranulomatous inflammationInflammatory disordersAvid lesionsLesional tissueSarcoidosisJanus kinase-signal transducerSingle patientJAK inhibitorsJAK inhibitionKinase-signal transducerTofacitinibKinase inhibitorsActivator of transcriptionInternal organs
2019
Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis
Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ. Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis. JACC Cardiovascular Imaging 2019, 12: 1284-1287. PMID: 30846271, DOI: 10.1016/j.jcmg.2019.01.011.Peer-Reviewed Original ResearchSURVIVAL FOLLOWING IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR IMPLANTATION IN PATIENTS WITH CARDIAC SARCOIDOSIS
Higgins A, Annapureddy A, Wang Y, Minges K, Lampert R, Rosenfeld L, Jacoby D, Curtis J, Miller E, Freeman J. SURVIVAL FOLLOWING IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR IMPLANTATION IN PATIENTS WITH CARDIAC SARCOIDOSIS. Journal Of The American College Of Cardiology 2019, 73: 306. DOI: 10.1016/s0735-1097(19)30914-3.Peer-Reviewed Original ResearchREPRODUCIBILITY AND OPTIMIZATION OF 18-FLUORO-DEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY FOR EVALUATION OF CARDIAC SARCOIDOSIS
Alvi R, Young B, Shahab Z, Pan H, Winkler J, Herzog E, Miller E. REPRODUCIBILITY AND OPTIMIZATION OF 18-FLUORO-DEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY FOR EVALUATION OF CARDIAC SARCOIDOSIS. Journal Of The American College Of Cardiology 2019, 73: 1659. DOI: 10.1016/s0735-1097(19)32265-x.Peer-Reviewed Original ResearchUsing FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis
Sharp MB, Soufer A, Abdelmessih M, Rosenfeld LE, Baldassarre LA, Miller EJ. Using FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis. Journal Of Nuclear Cardiology 2019, 27: 688-690. PMID: 30737635, DOI: 10.1007/s12350-019-01640-z.Peer-Reviewed Original Research
2017
A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology
Slart R, Glaudemans A, Lancellotti P, Hyafil F, Blankstein R, Schwartz R, Jaber W, Russell R, Gimelli A, Rouzet F, Hacker M, Gheysens O, Plein S, Miller E, Dorbala S, Donal E, Sciagra R, Bucerius J, Verberne H, Lindner O, Übleis C, Agostini D, Signore A, Edvardsen T, Neglia D, Beanlands R, Di Carli M, Chareonthaitawee P, Dilsizian V, Soman P, Habib G, Delgado V, Cardim N, Cosyns B, Flachskampf F, Gerber B, Haugaa K, Lombardi M, Masci P. A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology. European Heart Journal - Cardiovascular Imaging 2017, 18: 1073-1089. PMID: 28984894, DOI: 10.1093/ehjci/jex146.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCardiac Imaging TechniquesCardiologyCardiomyopathiesEuropeFemaleHumansMagnetic Resonance ImagingMaleMultimodal ImagingMyocardial Perfusion ImagingNuclear MedicinePositron Emission Tomography Computed TomographyPractice Guidelines as TopicRadionuclide ImagingSarcoidosisSocieties, MedicalUnited StatesConceptsCardiac sarcoidosisEuropean AssociationManagement of patientsCardiovascular magnetic resonanceMyocardial perfusion imagingPositron emission tomographyJoint position paperInfection committeeMulti-center dataClinical trialsSarcoidosisPerfusion imagingEmission tomographyCardiovascular imagingPosition statementAmerican SocietyNuclear cardiologyPosition paperNuclear medicineMagnetic resonanceAssociationCorrect useImagingEchocardiographyInflammation
2016
The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis
Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. Journal Of Nuclear Cardiology 2016, 24: 413-424. PMID: 27457527, DOI: 10.1007/s12350-016-0490-7.Peer-Reviewed Original ResearchConceptsFDG PET/CTPET/CTFDG uptakeCardiac sarcoidosisFDG PET/CT studiesPET/CT studiesImmunosuppressive treatmentCardiac inflammationPartial responseComplete resolutionImproved outcomesSUV thresholdImmunosuppressionFDG responseCT studiesPatientsCTSarcoidosisFurther studiesQuantitative changesUptakeResponseInflammationSUVmaxCMV
2015
Multimodality Imaging of Cardiac Sarcoidosis
Blankstein R, Miller E. Multimodality Imaging of Cardiac Sarcoidosis. 2015, 51-72. DOI: 10.1007/978-3-319-14624-9_7.ChaptersCardiac sarcoidosisCardiac MRIImaging testsHigh negative predictive valueExtra-cardiac diseasePreferred imaging testLate gadolinium enhancementFuture adverse eventsNegative predictive valueActive myocardial inflammationImmunosuppressive therapyCardiac involvementMyocardial inflammationAdverse eventsExcellent prognosisClinical criteriaReliable reference standardGadolinium enhancementSarcoidosisPredictive valueMultimodality imagingPatientsTherapyMRIDiagnosis