2021
Potential novel imaging targets of inflammation in cardiac sarcoidosis
Park J, Young BD, Miller EJ. Potential novel imaging targets of inflammation in cardiac sarcoidosis. Journal Of Nuclear Cardiology 2021, 29: 2171-2187. PMID: 34734365, DOI: 10.1007/s12350-021-02838-w.Peer-Reviewed Original ResearchConceptsCardiac sarcoidosisFDG-PET imagingPositron emission tomographyF-fluorodeoxyglucose positron emission tomographyNon-caseating granulomatous inflammationGranulomatous inflammationHigh morbiditySarcoid granulomasInflammatory diseasesPathognomonic featuresInflammationEmission tomographySarcoidosisMolecular targetsImaging targetsImagingMorbidityGranulomasMortalityDisease
2020
Advances in PET-Based Cardiac Amyloid Radiotracers
Gallegos C, Miller EJ. Advances in PET-Based Cardiac Amyloid Radiotracers. Current Cardiology Reports 2020, 22: 40. PMID: 32430600, DOI: 10.1007/s11886-020-01284-3.Peer-Reviewed Original ResearchConceptsPositron emission tomographyCardiac amyloidosisAmyloid depositionAmyloid radiotracersCardiac amyloid depositionCare of patientsTransthyretin cardiac amyloidosisCardiac imaging techniquesCongo red stainingPurpose of ReviewWeNovel positron emission tomographyEndomyocardial biopsyImaging featuresAmyloid depositsUnmet needInvasive methodEmission tomographyAmyloidosisGold standardAdditive valueRed stainingBiopsyFurther dataDiagnosisRecent studies
2019
Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis
Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ. Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis. JACC Cardiovascular Imaging 2019, 12: 1284-1287. PMID: 30846271, DOI: 10.1016/j.jcmg.2019.01.011.Peer-Reviewed Original ResearchREPRODUCIBILITY AND OPTIMIZATION OF 18-FLUORO-DEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY FOR EVALUATION OF CARDIAC SARCOIDOSIS
Alvi R, Young B, Shahab Z, Pan H, Winkler J, Herzog E, Miller E. REPRODUCIBILITY AND OPTIMIZATION OF 18-FLUORO-DEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY FOR EVALUATION OF CARDIAC SARCOIDOSIS. Journal Of The American College Of Cardiology 2019, 73: 1659. DOI: 10.1016/s0735-1097(19)32265-x.Peer-Reviewed Original ResearchChapter 9 Cardiac Sarcoidosis Questions for the Clinician
Varghese M, Shahab Z, Miller E. Chapter 9 Cardiac Sarcoidosis Questions for the Clinician. 2019, 105-113. DOI: 10.1016/b978-0-323-54429-0.00009-4.ChaptersCardiac sarcoidosisMagnetic resonance imagingImplantable cardiac defibrillator placementManagement of CSTreatment of CSDiagnosis of CSFluorodeoxyglucose positron emission tomographyCardiac magnetic resonance imagingNuances of treatmentUse of immunosuppressionPositron emission tomographySymptom reviewDefibrillator placementDiagnostic consensusMultiple guidelinesMultidisciplinary teamResonance imagingEmission tomographySelect groupDiagnosisControversial areasElectrocardiogramFurther testingTreatmentImmunosuppression
2018
Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients
Feher A, Srivastava A, Quail MA, Boutagy NE, Khanna P, Wilson L, Miller EJ, Liu YH, Lee F, Sinusas AJ. Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients. JACC Cardiovascular Imaging 2018, 13: 109-120. PMID: 30343093, PMCID: PMC6461525, DOI: 10.1016/j.jcmg.2018.08.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery DiseaseFemaleFractional Flow Reserve, MyocardialHeart TransplantationHumansMaleMiddle AgedMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsProspective StudiesRadiopharmaceuticalsReproducibility of ResultsRubidium RadioisotopesTime FactorsTreatment OutcomeConceptsPositron emission tomographyLong-term prognostic valueSerial assessmentPET-2Pet-1Cause mortalityHT patientsPrognostic valueHigh CFRLow CFRRb positron-emission tomographyEmission tomographyRb-82 positron emission tomographyRubidium-82 positron emission tomographyPET imagingHeart transplantation patientsHistory of HTCardiac allograft vasculopathyHeart transplant recipientsLong-term mortalitySingle-center studyMultivariate Cox regressionCoronary flow reserveAllograft vasculopathyHT recipientsIn Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents
Boutagy NE, Wu J, Cai Z, Zhang W, Booth CJ, Kyriakides TC, Pfau D, Mulnix T, Liu Z, Miller EJ, Young LH, Carson RE, Huang Y, Liu C, Sinusas AJ. In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents. JACC Basic To Translational Science 2018, 3: 378-390. PMID: 30062224, PMCID: PMC6058999, DOI: 10.1016/j.jacbts.2018.02.003.Peer-Reviewed Original ResearchLeft ventricular ejection fractionSuperoxide productionReactive oxygen speciesMarkers of ROSNovel positron emission tomography (PET) tracerEarly detectionMyocardial superoxide productionVentricular ejection fractionDoxorubicin-induced cardiotoxicityCardiac superoxide productionPositron emission tomography (PET) tracerPositron emission tomographyEmission tomography tracerEjection fractionCancer patientsCardiotoxicity detectionEmission tomographyTomography tracerCardiotoxicityReactive oxygen species (ROS) detectionWeeksOxygen speciesRodentsEchocardiographyPatients
2017
A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology
Slart R, Glaudemans A, Lancellotti P, Hyafil F, Blankstein R, Schwartz R, Jaber W, Russell R, Gimelli A, Rouzet F, Hacker M, Gheysens O, Plein S, Miller E, Dorbala S, Donal E, Sciagra R, Bucerius J, Verberne H, Lindner O, Übleis C, Agostini D, Signore A, Edvardsen T, Neglia D, Beanlands R, Di Carli M, Chareonthaitawee P, Dilsizian V, Soman P, Habib G, Delgado V, Cardim N, Cosyns B, Flachskampf F, Gerber B, Haugaa K, Lombardi M, Masci P. A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology. European Heart Journal - Cardiovascular Imaging 2017, 18: 1073-1089. PMID: 28984894, DOI: 10.1093/ehjci/jex146.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCardiac Imaging TechniquesCardiologyCardiomyopathiesEuropeFemaleHumansMagnetic Resonance ImagingMaleMultimodal ImagingMyocardial Perfusion ImagingNuclear MedicinePositron Emission Tomography Computed TomographyPractice Guidelines as TopicRadionuclide ImagingSarcoidosisSocieties, MedicalUnited StatesConceptsCardiac sarcoidosisEuropean AssociationManagement of patientsCardiovascular magnetic resonanceMyocardial perfusion imagingPositron emission tomographyJoint position paperInfection committeeMulti-center dataClinical trialsSarcoidosisPerfusion imagingEmission tomographyCardiovascular imagingPosition statementAmerican SocietyNuclear cardiologyPosition paperNuclear medicineMagnetic resonanceAssociationCorrect useImagingEchocardiographyInflammation