2018
Amygdala functional connectivity is associated with social impairments in preterm born young adults
Johns CB, Lacadie C, Vohr B, Ment LR, Scheinost D. Amygdala functional connectivity is associated with social impairments in preterm born young adults. NeuroImage Clinical 2018, 21: 101626. PMID: 30545688, PMCID: PMC6413301, DOI: 10.1016/j.nicl.2018.101626.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaBrain MappingChild DevelopmentFemaleHumansInfant, NewbornMagnetic Resonance ImagingMaleSocial BehaviorConceptsVineland Adaptive Behavior ScalesYouth Self-ReportAmygdala functional connectivitySocial impairmentChild Behavior ChecklistFunctional connectivityAmygdala connectivityPreterm participantsSocial functioningSocial functioning correlatesSocial functioning deficitsResting-state functional magnetic resonanceFunctional magnetic resonancePreterm-born adolescentsAdaptive Behavior ScalesAge 16Term-born peersEmotional developmentPreterm birth experienceParent reportDevelopmental trajectoriesRisk of depressionLate adolescentsBehavior ChecklistSelf-ReportMaternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior
Spann MN, Monk C, Scheinost D, Peterson BS. Maternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior. Journal Of Neuroscience 2018, 38: 2877-2886. PMID: 29487127, PMCID: PMC5852665, DOI: 10.1523/jneurosci.2272-17.2018.Peer-Reviewed Original ResearchConceptsMaternal immune activationC-reactive proteinFetal heart rate variabilityNeonatal functional connectivityInterleukin-6Postmenstrual ageImmune activationSalience networkFunctional connectivityPsychiatric disordersCRP levelsEpidemiological studiesMaternal C-reactive proteinResting-state imaging dataC-reactive protein levelsMaternal CRP levelsMaternal IL-6Months postmenstrual agePrenatal maternal immune activationSame psychiatric disordersWeeks postmenstrual ageIL-6 levelsAlters functional connectivityAltered brain developmentSame gestational age
2014
GABA, Resting-State Connectivity and the Developing Brain
Kwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR. GABA, Resting-State Connectivity and the Developing Brain. Neonatology 2014, 106: 149-155. PMID: 24970028, PMCID: PMC4134402, DOI: 10.1159/000362433.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidTerm-equivalent agePreterm infantsGABA concentrationTerm controlsFunctional connectivityMagnetic resonance imaging (MRI) scansFunctional magnetic resonance imaging (fMRI) scansResting-state functional connectivityRegional GABA concentrationTerm control groupResonance imaging scansResting-state connectivityRight frontal lobeConcentration of GABANAA/cholineMagnetic resonance spectroscopyPreclinical dataImaging scansFrontal lobeControl groupInfantsBrainMRI dataAge