2017
Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds
Vora A, Taank V, Dutta SM, Anderson JF, Fish D, Sonenshine DE, Catravas JD, Sultana H, Neelakanta G. Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds. Scientific Reports 2017, 7: 44593. PMID: 28300174, PMCID: PMC5353578, DOI: 10.1038/srep44593.Peer-Reviewed Original ResearchConceptsDifferent immune backgroundsImmune backgroundImmunodeficient animalsImmunocompetent animalsAge-matched miceAntibody-blocking assaysIxodes scapularis ticksFibrinogenolytic activityD-dimerAnti-hemostatic factorsImmune defenseTick feedingScapularis ticksReduced levelsBlood feedingEngorgement weightLC-MS/MSFibrinogenolysisNovel roleAnimalsPCR analysisTicksFeeding
1997
Inhibition of efficient polymerase chain reaction amplification of Borrelia burgdorferi DNA in blood-fed ticks.
Schwartz I, Varde S, Nadelman R, Wormser G, Fish D. Inhibition of efficient polymerase chain reaction amplification of Borrelia burgdorferi DNA in blood-fed ticks. American Journal Of Tropical Medicine And Hygiene 1997, 56: 339-42. PMID: 9129540, DOI: 10.4269/ajtmh.1997.56.339.Peer-Reviewed Original ResearchConceptsB. burgdorferi DNABorrelia burgdorferi DNAB. burgdorferiInfection rateB. burgdorferi infectionPolymerase chain reaction analysisUtility of PCRInhibitory substancesBurgdorferi infectionChain reaction analysisPCR analysisPositive PCR signalUnfed ticksPolymerase chain reaction amplificationBlood-feeding ticksChain reaction amplificationTick lysatesEngorged ticksPCR amplificationBlood mealSuch inhibitionBurgdorferiEquivalent cohortsReaction amplificationInhibitors