2001
Infection of Mice with the Agent of Human Granulocytic Ehrlichiosis after Different Routes of Inoculation
Hodzic E, Feng S, Fish D, Leutenegger C, Freet K, Barthold S. Infection of Mice with the Agent of Human Granulocytic Ehrlichiosis after Different Routes of Inoculation. The Journal Of Infectious Diseases 2001, 183: 1781-1786. PMID: 11372031, DOI: 10.1086/320735.Peer-Reviewed Original ResearchConceptsBone marrow samplesReal-time polymerase chain reactionPolymerase chain reactionHuman granulocytic ehrlichiosisMarrow samplesDay 20Granulocytic ehrlichiosisInfection of miceRate of infectionKinetics of infectionLymph nodesGene targetsInfected miceC3H miceEarly disseminationVascular perfusionDay 10Experimental infectionInfectionMiceNeedle inoculationChain reactionBloodEhrlichiosisInoculation
1998
Acquisition and Transmission of the Agent of Human Granulocytic Ehrlichiosis by Ixodes scapularis Ticks
Hodzic E, Fish D, Maretzki C, De Silva A, Feng S, Barthold S. Acquisition and Transmission of the Agent of Human Granulocytic Ehrlichiosis by Ixodes scapularis Ticks. Journal Of Clinical Microbiology 1998, 36: 3574-3578. PMID: 9817875, PMCID: PMC105242, DOI: 10.1128/jcm.36.12.3574-3578.1998.Peer-Reviewed Original ResearchConceptsInfected miceHuman granulocytic ehrlichiosisHGE agentIxodes scapularis ticksGranulocytic ehrlichiosisUninfected larval ticksAcquisition of infectionScapularis ticksMedian infectious doseLarval ticksNymphal ticksTick-borne transmissionC3H miceImmunodeficient miceInfectious doseMiceHuman isolatesInfectionOnset of feedingBloodEhrlichiosisPresent studyMammalian hostsCompetitive PCRTicksGranulocytic Ehrlichiosis in the Laboratory Mouse
Hodzic E, IJdo J, Feng S, Katavolos P, Sun W, Maretzki C, Fish D, Fikrig E, Telford S, Barthold S. Granulocytic Ehrlichiosis in the Laboratory Mouse. The Journal Of Infectious Diseases 1998, 177: 737-745. PMID: 9498456, DOI: 10.1086/514236.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisMouse passageGranulocytic ehrlichiosisHL-60 cell culturesPeripheral bloodC3H miceLate infectionEarly infectionCell culturesDay 17Day 5Blood smearsNormal valuesDay 24Polymerase chain reaction amplificationHGE agentChain reaction amplificationSpleen smearsMiceInfectionInfectivity assaysBloodLaboratory miceSmearsReaction amplification