2023
Does lower extremity fracture fixation technique influence neurologic outcomes in patients with traumatic brain injury? The EAST Brain vs. Bone multicenter trial
Ghneim M, Kufera J, Zhang A, Penaloza-Villalobos L, Swentek L, Watras J, Smith A, Hahn A, Mederos D, Dickhudt T, Laverick P, Cunningham K, Norwood S, Fernandez L, Jacobson L, Williams J, Lottenberg L, Azar F, Shillinglaw W, Slivinski A, Nahmias J, Donnelly M, Bala M, Egodage T, Zhu C, Udekwu P, Norton H, Dunn J, Baer R, McBride K, Santos A, Shrestha K, Metzner C, Murphy J, Schroeppel T, Stillman Z, O'Connor R, Johnson D, Berry C, Ratner M, Reynolds J, Humphrey M, Scott M, Hickman Z, Twelker K, Legister C, Glass N, Siebenburgen C, Palmer B, Semon G, Lieser M, McDonald H, Bugaev N, LeClair M, Stein D, Group T. Does lower extremity fracture fixation technique influence neurologic outcomes in patients with traumatic brain injury? The EAST Brain vs. Bone multicenter trial. Journal Of Trauma And Acute Care Surgery 2023, 95: 516-523. PMID: 37335182, DOI: 10.1097/ta.0000000000004095.Peer-Reviewed Original ResearchConceptsNeurologic outcomeFracture fixation techniquesIntramedullary nailingIMN groupTBI patientsGlasgow Coma Scale motor scoreHead Abbreviated Injury Scale scoreAbbreviated Injury Scale scoreFixation techniquesSevere lower extremity injuriesEx-fix groupRancho Los AmigosInjury Scale scoreProspective observational studyScale motor scoreLower extremity fracturesAge 18 yearsLower extremity injuriesTraumatic brain injuryMultivariable regression modelsHead AISORIF groupOperative interventionDefinitive managementExtremity fractures
2013
Successful Nonoperative Management of the Most Severe Blunt Renal Injuries: A Multicenter Study of the Research Consortium of New England Centers for Trauma
van der Wilden GM, Velmahos GC, Joseph DK, Jacobs L, DeBusk MG, Adams CA, Gross R, Burkott B, Agarwal S, Maung AA, Johnson DC, Gates J, Kelly E, Michaud Y, Charash WE, Winchell RJ, Desjardins SE, Rosenblatt MS, Gupta S, Gaeta M, Chang Y, de Moya MA. Successful Nonoperative Management of the Most Severe Blunt Renal Injuries: A Multicenter Study of the Research Consortium of New England Centers for Trauma. JAMA Surgery 2013, 148: 924-931. PMID: 23945834, DOI: 10.1001/jamasurg.2013.2747.Peer-Reviewed Original ResearchConceptsBlunt renal injuriesNonoperative managementNOM failureRenal injuryGrade IVFailure of NOMSevere blunt renal injuryRenal salvage rateSevere renal injuryRetrospective case seriesUrinary tract infectionMechanism of injurySuccessful nonoperative managementYears of ageRoad traffic crashesHemodynamic instabilityKidney injuryAdult patientsRenal failureStable patientsTract infectionsIndependent predictorsSalvage rateCase seriesNonoperative approach
2012
Compared to conventional ventilation, airway pressure release ventilation may increase ventilator days in trauma patients
Maung AA, Schuster KM, Kaplan LJ, Ditillo MF, Piper GL, Maerz LL, Lui FY, Johnson DC, Davis KA. Compared to conventional ventilation, airway pressure release ventilation may increase ventilator days in trauma patients. Journal Of Trauma And Acute Care Surgery 2012, 73: 507-510. PMID: 23019679, DOI: 10.1097/ta.0b013e31825ff653.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedContinuous Positive Airway PressureCritical CareDatabases, FactualFemaleFollow-Up StudiesHumansInjury Severity ScoreIntra-Abdominal HypertensionLength of StayLinear ModelsMaleMiddle AgedMultivariate AnalysisPulmonary Gas ExchangeRespiration, ArtificialRetrospective StudiesRisk AssessmentSurvival RateTime FactorsTrauma CentersTreatment OutcomeVentilator WeaningWounds and InjuriesConceptsAirway pressure release ventilationTotal ventilator daysVentilator daysHospital complicationsMechanical ventilationAIS scoreChest Abbreviated Injury Scale scoreAbbreviated Injury Scale scoreSpontaneous breathing trialAbdominal compartment syndromeAcute lung injuryAcute renal failureInjury Scale scoreStudy entry criteriaInjury Severity ScorePotential confounding factorsAPRV groupAPRV modeBreathing trialRescue therapyCompartment syndromeLung injuryRenal failureIndependent predictorsRetrospective reviewSuccessful Nonoperative Management of the Most Severe Blunt Liver Injuries: A Multicenter Study of the Research Consortium of New England Centers for Trauma
van der Wilden GM, Velmahos GC, Emhoff T, Brancato S, Adams C, Georgakis G, Jacobs L, Gross R, Agarwal S, Burke P, Maung AA, Johnson DC, Winchell R, Gates J, Cholewczynski W, Rosenblatt M, Chang Y. Successful Nonoperative Management of the Most Severe Blunt Liver Injuries: A Multicenter Study of the Research Consortium of New England Centers for Trauma. JAMA Surgery 2012, 147: 423-428. PMID: 22785635, DOI: 10.1001/archsurg.2012.147.Peer-Reviewed Original ResearchConceptsBlunt liver injurySuccessful nonoperative managementFailure of NOMNonoperative managementLiver injuryF-NOMIndependent predictorsSevere blunt liver injuryTrial of NOMGrade 4Level II trauma centerLiver-specific complicationsLife-threatening complicationsAbdominal organ injuriesRetrospective case seriesSystolic blood pressureLife-threatening eventsHemodynamic instabilityAdult patientsMajor sequelaeBlood pressureOrgan injuryCase seriesTrauma centerMulticenter study