2017
A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
Gremel G, Djureinovic D, Niinivirta M, Laird A, Ljungqvist O, Johannesson H, Bergman J, Edqvist P, Navani S, Khan N, Patil T, Sivertsson Å, Uhlén M, Harrison D, Ullenhag G, Stewart G, Pontén F. A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma. BMC Cancer 2017, 17: 9. PMID: 28052770, PMCID: PMC5215231, DOI: 10.1186/s12885-016-3030-6.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaCell carcinomaClear cell RCC patientsPrimary renal cell carcinomaPositive prognostic indicatorIndependent prognostic markerUnmet clinical needMalignant human tissuesNew diagnostic markersVenous tumorNodal statusBetter prognosisMetastatic lesionsNegative tumorsSystematic search strategyT stagePatient survivalPoor prognosisPositive tumorsRCC patientsPrognostic indicatorFuhrman gradePrognostic markerRCC cohortTissue microarray
2013
A systematic analysis of commonly used antibodies in cancer diagnostics
Gremel G, Bergman J, Djureinovic D, Edqvist P, Maindad V, Bharambe B, Khan W, Navani S, Elebro J, Jirström K, Hellberg D, Uhlén M, Micke P, Pontén F. A systematic analysis of commonly used antibodies in cancer diagnostics. Histopathology 2013, 64: 293-305. PMID: 24330150, DOI: 10.1111/his.12255.Peer-Reviewed Original ResearchConceptsDifferential diagnosticsCancer typesBenefit of immunohistochemistryTissue microarray cohortProstate-specific antigenEvidence-based dataCombination of antibodiesNumber of antibodiesMicroarray cohortMetastatic lesionsPrimary tumorClinical ImmunohistochemistryNovel markerImmunohistochemistryTumor samplesAntibodiesTumorsDiagnostic powerConsecutive sectionsDiagnostic antibodiesDifferent organsPresent studyPivotal roleCancer diagnosticsOptimal use