2023
CRP Versus SAA for Identification of Inflammatory Hepatic Adenomas
Soon G, Yasir S, Jain D, Kakar S, Wu T, Yeh M, Torbenson M, Chen Z. CRP Versus SAA for Identification of Inflammatory Hepatic Adenomas. Applied Immunohistochemistry & Molecular Morphology 2023, 31: 590-595. PMID: 37698958, DOI: 10.1097/pai.0000000000001155.Peer-Reviewed Original ResearchConceptsC-reactive proteinFocal nodular hyperplasiaHepatic adenomaInflammatory hepatic adenomaInflammatory adenomasNodular hyperplasiaH-scorePositive C-reactive proteinBeta-catenin activationProportion of casesInflammatory hepatocellular adenomaGlutamine synthetase stainingComplication riskRetrospective studyResection specimensPatient managementHepatocellular adenomaImmunohistochemical stainingSerum amyloidPositive stainingControl groupAdenomasIntense stainingMolecular classificationCRP staining
2021
HNF-1β is a More Sensitive and Specific Marker Than C-Reactive Protein for Identifying Biliary Differentiation in Primary Hepatic Carcinomas.
Patil PA, Taddei T, Jain D, Zhang X. HNF-1β is a More Sensitive and Specific Marker Than C-Reactive Protein for Identifying Biliary Differentiation in Primary Hepatic Carcinomas. Archives Of Pathology & Laboratory Medicine 2021, 146: 220-226. PMID: 34086854, DOI: 10.5858/arpa.2020-0725-oa.Peer-Reviewed Original Research
2013
Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma
Joseph NM, Ferrell LD, Jain D, Torbenson MS, Wu TT, Yeh MM, Kakar S. Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma. Modern Pathology 2013, 27: 62-72. PMID: 23807780, DOI: 10.1038/modpathol.2013.114.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Liver CellAdolescentAdultAgedBiomarkers, TumorBiopsyChildChild, PreschoolC-Reactive ProteinDiagnosis, DifferentialDiagnostic ErrorsFemaleFocal Nodular HyperplasiaGlutamate-Ammonia LigaseHumansImmunohistochemistryInflammation MediatorsLiver NeoplasmsMaleMiddle AgedPredictive Value of TestsSerum Amyloid A ProteinYoung AdultConceptsSerum amyloid-associated proteinFocal nodular hyperplasiaAmyloid-associated proteinsInflammatory hepatocellular adenomaNodular hyperplasiaHepatocellular adenomaStaining patternDuctular reactionFibrous stromaFocal nodular hyperplasia casesMap-like patternOverlapping histological featuresGlutamine synthetase stainingHistological featuresProtein immunohistochemistryHyperplasia casesIndeterminate lesionsPositive stainingHyperplasiaDiagnostic utilityAdenomasBlood vesselsFrequent overlapStainingDiagnostic errors