KRAS Mutations are Associated With Specific Morphologic Features in Colon Cancer
Gunal A, Hui P, Kilic S, Xu R, Jain D, Mitchell K, Robert M, Kenney B. KRAS Mutations are Associated With Specific Morphologic Features in Colon Cancer. Journal Of Clinical Gastroenterology 2013, 47: 509-514. PMID: 23090042, DOI: 10.1097/mcg.0b013e3182703030.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultColonic NeoplasmsFemaleHumansMaleMiddle AgedMutationProto-Oncogene ProteinsProto-Oncogene Proteins p21(ras)Ras ProteinsRetrospective StudiesConceptsKRAS mutation statusKRAS mutationsSpecific morphologic featuresColon cancerMorphologic featuresMutation statusAnti-epidermal growth factor receptor therapyDNA mismatch repair gene mutationsPeritumoral lymphocytic responseT3-T4 statusStage IV diseaseMismatch repair gene mutationsColon cancer resectionTime of resectionRight-sided locationRepair gene mutationsPearson χ2 testAdenocarcinoma morphologyKRAS testingCancer resectionLymphovascular invasionHistologic featuresReceptor therapyLymphocytic responseHistologic characteristics