1988
Prophylactic Treatment of intraocular Pressure Elevations after Neodymium:YAG Laser Posterior Capsulotomies and Extracapsular Cataract Extractions with Levobunolol
Silverstone D, Novack G, Kelley E, Chen K. Prophylactic Treatment of intraocular Pressure Elevations after Neodymium:YAG Laser Posterior Capsulotomies and Extracapsular Cataract Extractions with Levobunolol. Ophthalmology 1988, 95: 713-718. PMID: 3062528, DOI: 10.1016/s0161-6420(88)33124-6.Peer-Reviewed Original ResearchConceptsYAG laser posterior capsulotomyExtracapsular cataract extractionLaser posterior capsulotomyIntraocular pressure elevationLevobunolol groupPosterior capsulotomyVehicle groupMean IOPPressure elevationProphylactic treatmentCataract extractionPosterior chamber intraocular lensVehicle 1 hourPlacebo-controlled studyUnilateral NDElevated IOPIOP elevationProphylactic effectIntraocular lensLevobunololCapsulotomyMmHgIOPPatientsElevation
1985
Levobunolol A Beta-adrenoceptor Antagonist Effective in the Long-term Treatment of Glaucoma
Group T, Berson F, Epstein D, Partamian L, Cinotti A, Cohen H, Fries P, David R, Gurion B, Duzman E, Novack G, Lue J, Foerster R, Galin M, Lass J, Ober M, Scharrer A, Shin D, Silverstone D. Levobunolol A Beta-adrenoceptor Antagonist Effective in the Long-term Treatment of Glaucoma. Ophthalmology 1985, 92: 1271-1276. PMID: 2865710, DOI: 10.1016/s0161-6420(85)33887-3.Peer-Reviewed Original ResearchConceptsLong-term treatmentDouble-masked studyOcular hypotensive efficacyOcular hypotensive effectOpen-angle glaucomaMean heart rateConcentrations of levobunololTest medicationOcular hypertensionBlood pressureMean IOPSystemic reactionsOcular safetyEffective therapyHeart rateOphthalmic solutionGlaucomaLevobunololPatientsTwo-year periodTimololTreatmentHypertensionMedicationsIOP