2009
Molecular bases for sensitivity to figitumumab (CP-751,871) in NSCLC
Gualberto A, Dolled-Filhart M, Hixon M, Christensen J, Rimm D, Lee A, Wang Y, Pollak M, Paz-Ares L, Karp D. Molecular bases for sensitivity to figitumumab (CP-751,871) in NSCLC. Journal Of Clinical Oncology 2009, 27: 8091-8091. DOI: 10.1200/jco.2009.27.15_suppl.8091.Peer-Reviewed Original ResearchIGF-binding proteinsFree IGF-1IGF-IR overexpressionIGF-IR expressionNSCLC cell linesNSCLC ptsPlasma levelsIGF-1F trialsHigher IGF-IR expressionIGF type 1 receptorBioavailability of IGFIGF-IR pathwaySquamous cell tumorsType 1 receptorIGF-IR inhibitorCell linesLow E-cadherinE-cadherin expressionE-cadherin levelsPhase 2 activitySquamous NSCLCCell histologyClinical benefitSquamous cells
2001
Diagnosis of “ASCUS” in women over age 50 is less likely to be associated with dysplasia
Flynn K, Rimm D. Diagnosis of “ASCUS” in women over age 50 is less likely to be associated with dysplasia. Diagnostic Cytopathology 2001, 24: 132-136. PMID: 11169895, DOI: 10.1002/1097-0339(200102)24:2<132::aid-dc1026>3.0.co;2-n.Peer-Reviewed Original Research
1997
Degree of dysplasia following diagnosis of atypical squamous cells of undetermined significance is influenced by patient history and type of follow‐up
Ghoussoub R, Rimm D. Degree of dysplasia following diagnosis of atypical squamous cells of undetermined significance is influenced by patient history and type of follow‐up. Diagnostic Cytopathology 1997, 17: 14-19. PMID: 9218897, DOI: 10.1002/(sici)1097-0339(199707)17:1<14::aid-dc3>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsHigh-grade lesionsAtypical squamous cellsSelection of patientsGrade lesionsSquamous cellsUndetermined significanceDiagnosis of ASCUSSignificant past historyDegree of dysplasiaBethesda System criteriaASCUS diagnosisRetrospective studySignificant lesionsPatient historyVaginal smearsBiopsyCurrent literature findingsPatientsLesions
1996
Atypical reparative change on cervical/vaginal smears may be associated with dysplasia
Rimm D, Gmitro S, Frable W. Atypical reparative change on cervical/vaginal smears may be associated with dysplasia. Diagnostic Cytopathology 1996, 14: 374-379. PMID: 8725141, DOI: 10.1002/(sici)1097-0339(199605)14:4<374::aid-dc17>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsHigh-grade squamous intraepithelial lesionsLow-grade squamous intraepithelial lesionsAtypical reparative changesDiagnosis of ASCUSSquamous intraepithelial lesionsReparative changesIntraepithelial lesionsAtypical repairVaginal smearsSignificant histologic abnormalitiesUniversity Pathology DepartmentAtypical squamous cellsPercentage of casesChronic cervicitisSquamous cellsSquamous metaplasiaHistologic abnormalitiesHistologic findingsClinical managementHistologic changesCytologic diagnosisBethesda SystemClinical concernPathology departmentMedical College