2024
Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review
Barbieri P, Posa A, Lancellotta V, Madoff D, Maresca A, Cornacchione P, Tagliaferri L, Iezzi R. Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review. Current Oncology 2024, 31: 7403-7413. PMID: 39590176, PMCID: PMC11592455, DOI: 10.3390/curroncol31110546.Peer-Reviewed Original ResearchConceptsCRC liver metastasesLiver metastasesColorectal cancerComplete responseOverall survivalProgressive diseaseInclusion criteriaResection of CRC liver metastasesTreatment of CRC liver metastasisColorectal cancer liver metastasesSystematic searches of PubMedFrequent liver metastasesMedian overall survivalSecondary liver cancerFollow-up durationColorectal Liver MetastasesMultiple risk factorsCancer-related mortalitySearch of PubMedECT-related complicationsEvidence qualityLocoregional treatmentSurgical resectionIdentified articlesGRADE approachShort-Term Out-of-Pocket and Total Costs of Care After Ablation, Resection, or Transplant for Early-Stage Hepatocellular Carcinoma: A National SEER-Medicare Cost Comparison.
Charalel R, Mushlin A, Zheng X, Mao J, Carlos R, Brown R, Ibrahim S, Fortune B, Talenfeld A, Madoff D, Johnson M, Sedrakyan A. Short-Term Out-of-Pocket and Total Costs of Care After Ablation, Resection, or Transplant for Early-Stage Hepatocellular Carcinoma: A National SEER-Medicare Cost Comparison. American Journal Of Roentgenology 2024, 223: e2431272. PMID: 38899842, DOI: 10.2214/ajr.24.31272.Peer-Reviewed Original ResearchEarly-stage hepatocellular carcinomaHepatocellular carcinomaPost-procedure periodIndex procedureOut-of-pocket costsPatient out-of-pocket costsDrivers of high costsDays post-procedureSubgroup of patientsTreated with ablationPropensity-matched subgroupsU.S. population-based studyPopulation-based studySurgical resectionMultivariate linear regression modelSurgical treatmentPrognostic indicatorPost-procedureTreatment modalitiesTreatment optionsSEER-MedicareResectionMultivariate analysisTransplantationPropensity-score
2023
Predictors for Early Liver Cancer Survival After Ablation and Surgical Resection: A Surveillance, Epidemiology, and End Results Program-Medicare Study
Charalel R, Mushlin A, Zheng X, Mao J, Carlos R, Brown R, Fortune B, Talenfeld A, Madoff D, Ibrahim S, Johnson M, Sedrakyan A. Predictors for Early Liver Cancer Survival After Ablation and Surgical Resection: A Surveillance, Epidemiology, and End Results Program-Medicare Study. Journal Of The American College Of Radiology 2023, 21: 295-308. PMID: 37922972, DOI: 10.1016/j.jacr.2023.10.017.Peer-Reviewed Original ResearchCancer-specific mortalityCancer-specific deathSurgical resectionSocial determinantsPortal hypertensionTumor sizeTreatment characteristicsSmall HCCAsian raceDisease factorsMultivariable Cox regression modelsSEER-Medicare studyChronic kidney diseaseHigh-volume centersLarger tumor sizeCox regression modelSignificant protective factorCause mortalityClinical factorsEsophageal varicesIndependent predictorsSEER-MedicareKidney diseaseVolume centersProcedure yearBeyond Survival: Adverse Events and Care Delivery Outcomes after Early Liver Cancer Treatment in a Nationally Representative Cohort
Charalel R, Mushlin A, Zheng X, Mao J, Carlos R, Brown R, Fortune B, Talenfeld A, Madoff D, Ibrahim S, Johnson M, Sedrakyan A. Beyond Survival: Adverse Events and Care Delivery Outcomes after Early Liver Cancer Treatment in a Nationally Representative Cohort. Journal Of Vascular And Interventional Radiology 2023, 34: 1997-2005.e3. PMID: 37468093, DOI: 10.1016/j.jvir.2023.07.010.Peer-Reviewed Original ResearchConceptsLiver transplantSurgical resectionHepatocellular carcinomaLT cohortBiliary injuryReadmission ratesAbscess formationIntensive care unit-level careLess healthcare utilizationNationally Representative CohortInitial hospital stayICU-level careAdverse event ratesEnd Results ProgramSmall hepatocellular carcinomaCare delivery outcomesFisher's exact testHealthcare Common Procedure Coding SystemChi-square testLow-intensity careLiver cancer treatmentPostprocedural hemorrhageHospital stayAdverse eventsSecondary outcomes
2022
Long-Term Survival After Surgery Versus Ablation for Early Liver Cancer in a Large, Nationally Representative Cohort
Charalel RA, Mushlin AI, Li D, Mao J, Ibrahim S, Carlos R, Kwan SW, Fortune B, Talenfeld AD, Brown RS, Madoff DC, Johnson MS, Sedrakyan A. Long-Term Survival After Surgery Versus Ablation for Early Liver Cancer in a Large, Nationally Representative Cohort. Journal Of The American College Of Radiology 2022, 19: 1213-1223. PMID: 36208842, DOI: 10.1016/j.jacr.2022.07.010.Peer-Reviewed Original ResearchConceptsCancer-specific survivalSurgical resectionSmall hepatocellular carcinomaPrior treatment groupsHepatocellular carcinomaSurvival outcomesTreatment groupsSR groupPrior treatmentEnd Results Program-MedicarePropensity-matched hazard ratiosPropensity score-matched comparisonMedian study followNationally Representative CohortCancer-specific mortalityDisease-free survivalCox regression analysisKaplan-Meier curvesLog-rank testEarly liver cancerDifferential survival outcomesHealthcare Common Procedure Coding SystemCause mortalityCause survivalLiver transplant
2020
3:00 PM Abstract No. 32 Ablation versus surgical resection for small hepatocellular carcinoma: a risk-adjusted SEER-Medicare analysis
Charalel R, Mao J, Li S, Kwan S, Brunner M, Talenfeld A, Madoff D, Abramson E, Fortune B, Ibrahim S, Mushlin A, Sedrakyan A. 3:00 PM Abstract No. 32 Ablation versus surgical resection for small hepatocellular carcinoma: a risk-adjusted SEER-Medicare analysis. Journal Of Vascular And Interventional Radiology 2020, 31: s18-s19. DOI: 10.1016/j.jvir.2019.12.054.Peer-Reviewed Original Research
2018
Role of interventional radiology in the management of hepatocellular carcinoma: current status.
Holzwanger DJ, Madoff DC. Role of interventional radiology in the management of hepatocellular carcinoma: current status. Chinese Clinical Oncology 2018, 7: 49. PMID: 30180753, DOI: 10.21037/cco.2018.07.04.Peer-Reviewed Original ResearchConceptsEarly-stage diseaseStage diseaseHepatocellular carcinomaBarcelona Clinic Liver CancerIntermediate-grade diseaseGold standard therapyTrans-arterial chemoembolizationAvailable treatment optionsTreatment of patientsAdequate oncologic controlAdvanced diseaseLiver transplantationPalliative interventionsPerformance statusStandard therapySurgical resectionGrade diseaseOncologic controlLiver functionTreatment optionsRadiofrequency ablationEffective therapyLiver cancerBetter outcomesClinical practice
2017
Portal Vein Embolization in the Treatment of Metastatic Colorectal Cancer: Optimal Approach and Current Controversies
Gans D, Siegel C, Patel I, Tavri S, Madoff D, Sutter C. Portal Vein Embolization in the Treatment of Metastatic Colorectal Cancer: Optimal Approach and Current Controversies. Digestive Disease Interventions 2017, 01: 171-183. DOI: 10.1055/s-0037-1606204.Peer-Reviewed Original ResearchPreoperative portal vein embolizationMetastatic colorectal cancerPortal vein embolizationPortal vein ligationSurgical alternativeSurgical resectionVein embolizationVein ligationColorectal cancerResectable metastatic colorectal cancerColorectal carcinoma metastaticNew surgical alternativeResidual liver volumeSubsequent surgical resectionTreatment of patientsLiver volume measurementCurrent controversiesCarcinoma metastaticLiver metastasesMetastatic diseaseLobe hypertrophyPatient selectionProper liver functionLiver functionLiver partition