1991
Conversion of a human B cell lymphoma line by Epstein-Barr virus is associated with increased tyrosine phosphorylation of a 50 kilodalton cytosolic protein
Lacy J, Bartiss A, Coleman D. Conversion of a human B cell lymphoma line by Epstein-Barr virus is associated with increased tyrosine phosphorylation of a 50 kilodalton cytosolic protein. Virus Research 1991, 20: 85-96. PMID: 1656626, DOI: 10.1016/0168-1702(91)90063-2.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusB cellsHuman B cellsB-cell lymphoma linePresence of EBVLymphoma linesProtein tyrosine phosphorylationEBV infectionHuman B cell lymphoma lineTyrosine phosphorylationB lymphocytesImmortalized lymphoblastoid cellsBiochemical changesLymphoblastoid cellsInfectionEndogenous tyrosine kinasesContinuous proliferationCytosolic proteinsTyrosine kinaseVirusCellsPhosphorylationPhosphotyrosine antibodiesLymphocytesProtein
1990
Interleukin 6 is an autocrine growth factor for mesangial cells
Ruef C, Budde K, Lacy J, Northemann W, Baumann M, Sterzel R, Coleman D. Interleukin 6 is an autocrine growth factor for mesangial cells. Kidney International 1990, 38: 249-257. PMID: 2402117, DOI: 10.1038/ki.1990.193.Peer-Reviewed Original ResearchConceptsIL-6Autocrine growth factorInterleukin-6T cellsGrowth factorSecrete IL-6Possible paracrine roleAcute phase responseIL-6 mRNADose-dependent increaseIL-6 actsMesangial cell proliferationIL-6 resultsGlomerular inflammationNumber of MCsImmune responseRat MCsParacrine roleB cellsMesangial cellsMC-CMEndothelial cellsAutocrine signalsCell proliferationPlasmacytoma cells