2001
Calpain Cleavage Promotes Talin Binding to the β3Integrin Cytoplasmic Domain*
Yan B, Calderwood D, Yaspan B, Ginsberg M. Calpain Cleavage Promotes Talin Binding to the β3Integrin Cytoplasmic Domain*. Journal Of Biological Chemistry 2001, 276: 28164-28170. PMID: 11382782, DOI: 10.1074/jbc.m104161200.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsAntigens, CDBiotinBlood PlateletsCalpainCytoplasmCytoskeletonDNA, ComplementaryDose-Response Relationship, DrugGas Chromatography-Mass SpectrometryHumansIntegrin beta3IntegrinsKineticsMolecular Sequence DataPlatelet Membrane GlycoproteinsProtein BindingProtein Structure, TertiaryRatsRecombinant ProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSurface Plasmon ResonanceTalinTime Factors
1995
Integrin α2 I-domain is a binding site for collagens
Tuckwell D, Calderwood D, Green L, Humphries M. Integrin α2 I-domain is a binding site for collagens. Journal Of Cell Science 1995, 108: 1629-1638. PMID: 7615681, DOI: 10.1242/jcs.108.4.1629.Peer-Reviewed Original ResearchConceptsAlpha 2 beta 1Alpha 1 beta 1I-domainIntegrin alpha 2 beta 1Beta 1N-terminal regionMajor cellular receptorAlpha 2 subunitIntegrins alpha 1 beta 1Complete receptorBacterial expressionAnti-functional antibodiesCollagen-binding domainA-domainInhibits cellAmino acidsCollagen specificityCellular receptorsXI collagenConcentration-dependent mannerVon Willebrand factorAlpha 1BindingWillebrand factorHomology