2024
Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis
Hussain N, Ma C, Hirschfield G, Walmsley M, Hanford P, Vesterhus M, Kowdley K, Bergquist A, Ponsioen C, Levy C, Assis D, Schramm C, Bowlus C, Trauner M, Aiyegbusi O, Jairath V, Trivedi P. Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis. BMJ Open 2024, 14: e080143. PMID: 38926149, PMCID: PMC11216047, DOI: 10.1136/bmjopen-2023-080143.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisClinical trialsSclerosing cholangitisCore outcome setImmune-mediated liver diseasesPrimary sclerosing cholangitis treatmentOutcome measuresEvaluate novel therapiesSlow disease progressionPatient-reported outcome measuresMedical therapyNovel therapiesLiver fibrosisDisease progressionHistological assessmentLiver diseaseInternational two-round Delphi surveyImaging-based biomarkersIntervention trialsTherapyConsensus meetingHealthcare payersCholangitisSemistructured qualitative interviewsTwo-round Delphi survey
2019
2797 Fenofibrate and PSC: A Case Series From a Single Center Liver Registry
Shah S, Silveira M, Assis D, Cusack L. 2797 Fenofibrate and PSC: A Case Series From a Single Center Liver Registry. The American Journal Of Gastroenterology 2019, 114: s1544-s1545. DOI: 10.14309/01.ajg.0000600720.33625.bb.Peer-Reviewed Original ResearchPrimary sclerosing cholangitisPrimary biliary cholangitisCase seriesUrsodeoxycholic acidLarge-duct primary sclerosing cholangitisTreatment of primary sclerosing cholangitisNo current effective therapyRetrospective single-center case seriesPrimary sclerosing cholangitis patientsSingle-center case seriesAlkaline phosphataseRisk scorePrimary sclerosing cholangitis treatmentPost-FFSAlkaline phosphatase reductionPatients due to lackAcute kidney injuryCholestatic liver diseaseAlkaline phosphatase levelsCurrent effective therapiesSerum alkaline phosphataseInflammatory bowel diseaseIntrahepatic diseaseAutoimmune hepatitisRecurrent cholangitis