2024
Antibiotic prescribing for acute respiratory infections during the coronavirus disease 2019 (COVID-19) pandemic: Patterns in a nationwide telehealth service provider
Linder J, Persell S, Kelley M, Friedberg M, Goldstein N, Knight T, Kaiser K, Doctor J, Mack W, Tibbels J, McCabe B, Haenchen S, Meeker D. Antibiotic prescribing for acute respiratory infections during the coronavirus disease 2019 (COVID-19) pandemic: Patterns in a nationwide telehealth service provider. Infection Control And Hospital Epidemiology 2024, 45: 777-780. PMID: 38329093, PMCID: PMC11102822, DOI: 10.1017/ice.2023.292.Peer-Reviewed Original Research
2022
The protocol of improving safe antibiotic prescribing in telehealth: A randomized trial
McCabe B, Linder J, Doctor J, Friedberg M, Fox C, Goldstein N, Knight T, Kaiser K, Tibbels J, Haenchen S, Persell S, Warberg R, Meeker D. The protocol of improving safe antibiotic prescribing in telehealth: A randomized trial. Contemporary Clinical Trials 2022, 119: 106834. PMID: 35724841, DOI: 10.1016/j.cct.2022.106834.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsInappropriate antibiotic prescribingAntibiotic prescribing ratesAntibiotic prescribingPrescribing ratesRandomized quality improvement trialAntibiotic stewardship interventionsInappropriate antibiotic prescriptionsUrgent care visitsPrevious randomized trialsPrimary care clinicsQuality improvement trialEffective antibiotic useElectronic health recordsARI visitsInappropriate prescribingAntibiotic prescriptionsCare visitsSecondary outcomesPrimary outcomeRespiratory infectionsCare clinicsRandomized trialsStewardship interventionsAntibiotic use
2019
A Multifaceted Intervention Improves Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings
Yadav K, Meeker D, Mistry R, Doctor J, Fleming‐Dutra K, Fleischman R, Gaona S, Stahmer A, May L. A Multifaceted Intervention Improves Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings. Academic Emergency Medicine 2019, 26: 719-731. PMID: 31215721, PMCID: PMC8146207, DOI: 10.1111/acem.13690.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsEmergency departmentARI visitsRespiratory infectionsStewardship interventionsUrgent care center visitsViral acute respiratory infectionsHierarchical mixed-effects logistic regression modelsCluster-randomized clinical trialHealth systemAntibiotic stewardship interventionsUrgent care settingsOutpatient antibiotic prescriptionsPediatric emergency departmentMixed effects logistic regression modelsAcademic health systemLogistic regression modelsInappropriate prescribingAntibiotic prescribingAntibiotic prescriptionsInappropriate prescriptionsInfluenza seasonAntibiotic stewardshipClinical trialsOdds ratio
2018
1633. A Multifaceted Intervention to Improve Prescribing for Acute Respiratory Infection in Adults and Children in Emergency Department and Urgent Care Settings (MITIGATE Trial)
Yadav K, Meeker D, Mistry R, Doctor J, Fleming-Dutra K, Fleischman R, Gaona S, Stahmer A, May L. 1633. A Multifaceted Intervention to Improve Prescribing for Acute Respiratory Infection in Adults and Children in Emergency Department and Urgent Care Settings (MITIGATE Trial). Open Forum Infectious Diseases 2018, 5: s43-s43. PMCID: PMC6252972, DOI: 10.1093/ofid/ofy209.103.Peer-Reviewed Original ResearchAcute respiratory infectionsEmergency departmentRespiratory infectionsAntibiotic useCare settingsUrgent care center visitsViral acute respiratory infectionsHierarchical mixed-effects logistic regression modelsHealth systemOverall antibiotic prescribingUnnecessary antibiotic useUrgent care settingsAcute care settingInappropriate antibiotic usePediatric emergency departmentMixed effects logistic regression modelsAcademic health systemLow baseline ratesEffects logistic regression modelsImplementation science strategiesLogistic regression modelsARI visitsInappropriate prescribingAdverse eventsAntibiotic prescribingBehavioral Economics Interventions to Improve Outpatient Antibiotic Prescribing for Acute Respiratory Infections: a Cost-Effectiveness Analysis
Gong C, Zangwill K, Hay J, Meeker D, Doctor J. Behavioral Economics Interventions to Improve Outpatient Antibiotic Prescribing for Acute Respiratory Infections: a Cost-Effectiveness Analysis. Journal Of General Internal Medicine 2018, 34: 846-854. PMID: 29740788, PMCID: PMC6544688, DOI: 10.1007/s11606-018-4467-x.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsQuality-adjusted life yearsInappropriate antibiotic prescriptionsAntibiotic prescriptionsBehavioral economic interventionsElectronic health recordsAntibiotic prescribingRespiratory infectionsProvider educationAccountable justificationSymptoms of ARIComputerized clinical decision supportIncremental cost-effectiveness ratioOutpatient antibiotic prescribingInappropriate antibiotic prescribingAssociated adverse eventsHealthcare resource utilizationTotal quality-adjusted life yearsHigher quality-adjusted life yearsCost-effectiveness ratioCDC surveillance dataPatients' electronic health recordsCost-effectiveness analysisUS societal perspectiveAdverse events
2016
Prescriber preferences for behavioural economics interventions to improve treatment of acute respiratory infections: a discrete choice experiment
Gong C, Hay J, Meeker D, Doctor J. Prescriber preferences for behavioural economics interventions to improve treatment of acute respiratory infections: a discrete choice experiment. BMJ Open 2016, 6: e012739. PMID: 27660322, PMCID: PMC5051402, DOI: 10.1136/bmjopen-2016-012739.Peer-Reviewed Original ResearchDiscrete choice experimentBehavioral economic interventionsChoice experimentStated preferencesEconomic interventionsSuggested alternativesInappropriate antibiotic prescribingWTP estimatesNon-antibiotic treatment optionsPeer comparisonPerformance incentivesAntibiotic prescribingAccountable justificationPrescriber preferencePreferencesEffective interventionsActual behaviorAntibiotic prescribing ratesAcute respiratory infectionsPrimary care centersPrimary care providersIncentivesPrescribing ratesPayRespiratory infectionsBehavioral interventions to reduce inappropriate antibiotic prescribing: a randomized pilot trial
Persell S, Doctor J, Friedberg M, Meeker D, Friesema E, Cooper A, Haryani A, Gregory D, Fox C, Goldstein N, Linder J. Behavioral interventions to reduce inappropriate antibiotic prescribing: a randomized pilot trial. BMC Infectious Diseases 2016, 16: 373. PMID: 27495917, PMCID: PMC4975897, DOI: 10.1186/s12879-016-1715-8.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAnti-Bacterial AgentsBehaviorDecision MakingDecision Support Systems, ClinicalEducation, Medical, ContinuingFemaleHumansInappropriate PrescribingInterprofessional RelationsMaleMiddle AgedPharyngitisPhysicians, Primary CarePilot ProjectsPractice Patterns, Physicians'PrescriptionsRespiratory Tract InfectionsSinusitisConceptsAcute respiratory infectionsInappropriate antibiotic prescribingAntibiotic prescribingRespiratory infectionsDiagnosis/symptomsARI diagnosesBehavioral interventionsAntibiotic prescribing ratesRandomized pilot trialPre-intervention yearInappropriate prescribingPrescribing ratesCare cliniciansAccountable justificationPilot trialPrescribingIntervention yearPharyngitisInfectionFloor effectsSymptomsDiagnosisPeer comparisonInterventionHawthorne effectCognitive reflection and antibiotic prescribing for acute respiratory infections
Pineros D, Doctor J, Friedberg M, Meeker D, Linder J. Cognitive reflection and antibiotic prescribing for acute respiratory infections. Family Practice 2016, 33: 309-311. PMID: 27006411, PMCID: PMC4931815, DOI: 10.1093/fampra/cmw015.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsAntibiotic prescribing ratesAntibiotic prescribingPrescribing ratesRespiratory infectionsCommon clinical decisionsPrescription of antibioticsElectronic health record dataPrimary care practicesHealth record dataCare practicesClinicians' tendenciesClinical decisionPrescribingRecord dataCliniciansInfectionAntibioticsHigher scoresScoresPsychological testsCare
2014
Nudging Physician Prescription Decisions by Partitioning the Order Set: Results of a Vignette-Based Study
Tannenbaum D, Doctor J, Persell S, Friedberg M, Meeker D, Friesema E, Goldstein N, Linder J, Fox C. Nudging Physician Prescription Decisions by Partitioning the Order Set: Results of a Vignette-Based Study. Journal Of General Internal Medicine 2014, 30: 298-304. PMID: 25394536, PMCID: PMC4351289, DOI: 10.1007/s11606-014-3051-2.Peer-Reviewed Original ResearchConceptsEHR order setsPrimary care providersElectronic health recordsNarrow-spectrum antibioticsOrder setsTreatment menuTreatment choiceCare providersMain MeasuresThe main outcomeAggressive treatment optionsAcute respiratory infectionsPhysician prescription decisionsBroad-spectrum antibioticsRespiratory infectionsPrescribing practicesCounter medicationsTreatment optionsPrescription decisionsMAIN OUTCOMEPatient careTypical signsBackgroundHealthcare professionalsPrescription drugsProvider decisionsAggressive optionsNudging Guideline-Concordant Antibiotic Prescribing: A Randomized Clinical Trial
Meeker D, Knight T, Friedberg M, Linder J, Goldstein N, Fox C, Rothfeld A, Diaz G, Doctor J. Nudging Guideline-Concordant Antibiotic Prescribing: A Randomized Clinical Trial. JAMA Internal Medicine 2014, 174: 425-431. PMID: 24474434, PMCID: PMC4648560, DOI: 10.1001/jamainternmed.2013.14191.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsInappropriate antibiotic prescribingAntibiotic prescribing ratesPrescribing ratesAntibiotic prescribingClinical trialsIntervention periodOutpatient primary care clinicsInappropriate prescribing ratePrimary care clinicsAppropriate antibiotic prescriptionRandomized clinical trialsExamination roomLow-cost interventionStandard practice controlsQuality improvement effortsARI diagnosesARI visitsAntibiotic prescriptionsPatient ageRespiratory infectionsCare clinicsInsurance statusMAIN OUTCOMEClinical practice
2013
Use of behavioral economics and social psychology to improve treatment of acute respiratory infections (BEARI): rationale and design of a cluster randomized controlled trial [1RC4AG039115-01] - study protocol and baseline practice and provider characteristics
Persell S, Friedberg M, Meeker D, Linder J, Fox C, Goldstein N, Shah P, Knight T, Doctor J. Use of behavioral economics and social psychology to improve treatment of acute respiratory infections (BEARI): rationale and design of a cluster randomized controlled trial [1RC4AG039115-01] - study protocol and baseline practice and provider characteristics. BMC Infectious Diseases 2013, 13: 290. PMID: 23806017, PMCID: PMC3701464, DOI: 10.1186/1471-2334-13-290.Peer-Reviewed Original ResearchConceptsAcute respiratory infectionsInappropriate antibiotic prescribingAntibiotic prescribingInappropriate prescribingRespiratory infectionsComputerized clinical decision supportAntibiotic prescribing ratesTrial study protocolInappropriate antibiotic useAdverse drug eventsCost of careUnit of randomizationPatients' electronic health recordsElectronic health recordsPersistence of effectsARI diagnosesNonbacterial infectionsAntibiotic prescriptionsSecondary outcomesClinical decision supportPrescribing ratesPrimary outcomeBehavioral economic strategiesGuideline recommendationsYear follow