2001
Using reporter genes to label selected neuronal populations in transgenic mice for gene promoter, anatomical, and physiological studies
Spergel D, Krüth U, Shimshek D, Sprengel R, Seeburg P. Using reporter genes to label selected neuronal populations in transgenic mice for gene promoter, anatomical, and physiological studies. Progress In Neurobiology 2001, 63: 673-686. PMID: 11165000, DOI: 10.1016/s0301-0082(00)00038-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGreen fluorescent proteinReporter geneGene promoterSubcellular localization signalsCell type-specific expressionPromoter-driven reporter geneCorresponding reporter genesType-specific expressionLocalization signalReporter proteinNeuronal populationsPromoter elementsTransgenic miceFluorescent proteinTransgenic expressionGenesCell typesGonadotropin-releasing hormone (GnRH) neuronsGnRH neuronal networkPhysiological studiesPromoterProteinHormone neuronsBla genesExpression
1986
Segmental differentiation in the leech nervous system: The genesis of cell number in the segmental ganglia of haemopis marmorata
Stewart RR, Spergel D, Macagno ER. Segmental differentiation in the leech nervous system: The genesis of cell number in the segmental ganglia of haemopis marmorata. The Journal Of Comparative Neurology 1986, 253: 253-259. PMID: 3793993, DOI: 10.1002/cne.902530211.Peer-Reviewed Original ResearchConceptsDifferential cell deathPostembryonic developmentHirudinid leechesSegmental gangliaCell deathDifferential cell proliferationExtra cellsHaemopis marmorataCell proliferationSegmental differentiationSexual organsEarly developmentAdult numbersLeech nervous systemAdditional cellsCell additionCell numberCellsMore cellsSex gangliaAdult complementMidbody gangliaNervous systemNeuronal populationsGanglia