2019
Modulation of Gonadotropin-Releasing Hormone Neuron Activity and Secretion in Mice by Non-peptide Neurotransmitters, Gasotransmitters, and Gliotransmitters
Spergel DJ. Modulation of Gonadotropin-Releasing Hormone Neuron Activity and Secretion in Mice by Non-peptide Neurotransmitters, Gasotransmitters, and Gliotransmitters. Frontiers In Endocrinology 2019, 10: 329. PMID: 31178828, PMCID: PMC6538683, DOI: 10.3389/fendo.2019.00329.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGnRH neuron activityGnRH secretionNeuron activityNon-peptide neurotransmittersGnRH neuronsGonadotropin-Releasing Hormone Neuron ActivityMouse GnRH neuronsProstaglandin E2Central regulationAdult miceGliotransmittersMouse studiesNitric oxideSecretionNeurotransmittersDirect modulationMiceNeuronsGasotransmitterFurther explorationGonadotropinModulationActivityGABAPostnatal
1999
GABA- and Glutamate-Activated Channels in Green Fluorescent Protein-Tagged Gonadotropin-Releasing Hormone Neurons in Transgenic Mice
Spergel D, Krüth U, Hanley D, Sprengel R, Seeburg P. GABA- and Glutamate-Activated Channels in Green Fluorescent Protein-Tagged Gonadotropin-Releasing Hormone Neurons in Transgenic Mice. Journal Of Neuroscience 1999, 19: 2037-2050. PMID: 10066257, PMCID: PMC6782541, DOI: 10.1523/jneurosci.19-06-02037.1999.Peer-Reviewed Original ResearchConceptsGnRH neuronsPreoptic areaNucleated patchesWhole-cell recordingsApplication of GABANMDA receptor channelsGanglion terminaleHormone neuronsOrganum vasculosumSeptal nucleusDiagonal bandLamina terminalisNeuronal somataAxon terminalsOlfactory bulbMedian eminenceTransgenic miceFiring patternsNeuronsNeuronal dendritesReceptor channelsGABAGreen fluorescent proteinL-glutamateAMPA
1994
Gonadotropin-releasing hormone neurons Intrinsic pulsatility and receptor-mediated regulation
Stojilkovic S, Krsmanovic L, Spergel D, Catt K. Gonadotropin-releasing hormone neurons Intrinsic pulsatility and receptor-mediated regulation. Trends In Endocrinology And Metabolism 1994, 5: 201-209. PMID: 18407209, DOI: 10.1016/1043-2760(94)90078-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGnRH neuronsGonadotropin-releasing hormone releaseImmortalized GnRH neuronsIndividual GnRH neuronsGnRH pulse generatorPulse generator activityReceptor-mediated regulationGnRH releaseSynaptic contactsHormone releasePulsatile patternGenerator activityNeuronsEpisodic patternSecretory mechanismCell typesPulse generatorEndothelinGnRHGonadotropinHypothalamusAgonistsCatecholaminesGABAPulsatility