2013
Decreased food pleasure and disrupted satiety signals in chronic low back pain
Geha P, deAraujo I, Green B, Small DM. Decreased food pleasure and disrupted satiety signals in chronic low back pain. Pain 2013, 155: 712-722. PMID: 24384160, DOI: 10.1016/j.pain.2013.12.027.Peer-Reviewed Original ResearchConceptsChronic low back painCLBP patientsLow back painHealthy controlsBack painSugary drinksFat calorie intakeHedonic perceptionSatiety signalsCalorie intakePatientsIntake testFood pleasureFunctional brainAd libitumPotential mechanismsPainObesityIntakeStructural alterationsPhysiological mechanismsHedonic ratingsAlterationsDrinksSensory evaluation
2012
Acute stress potentiates brain response to milkshake as a function of body weight and chronic stress
Rudenga KJ, Sinha R, Small DM. Acute stress potentiates brain response to milkshake as a function of body weight and chronic stress. International Journal Of Obesity 2012, 37: 309-316. PMID: 22430303, PMCID: PMC3381866, DOI: 10.1038/ijo.2012.39.Peer-Reviewed Original ResearchConceptsBody mass indexFunctional magnetic resonance imagingChronic stressOrbitofrontal cortexRight amygdalaBody weightPalatable foodAcute stressBasal cortisol levelsBrain responsesAmygdala responseMagnetic resonance imagingStress-related eatingMilkshake receiptPalatable milkshakeObese womenOverweight womenMass indexRight amygdala responseOFC responsesPotentiates responsesCortisol levelsLeft amygdalaResonance imagingVentral striatum
2005
Increased taste intensity perception exhibited by patients with chronic back pain
Small DM, Apkarian A. Increased taste intensity perception exhibited by patients with chronic back pain. Pain 2005, 120: 124-130. PMID: 16360267, DOI: 10.1016/j.pain.2005.10.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultBack PainChronic DiseaseDifferential ThresholdFemaleHumansMaleMiddle AgedTasteTaste ThresholdVisual PerceptionConceptsChronic back painCBP patientsBack painControl subjectsSpecific brain sitesSpecific brain abnormalitiesSuprathreshold taste intensityCortical injuryTaste disturbanceBrain atrophyTaste intensity perceptionPain perceptionBrain abnormalitiesBrain sitesPainBrain regionsSense of tastePatientsGustatory stimuliBitter stimuliRecognition thresholdSubjectsVisual assessmentFurther evidenceSpecific patterns