2016
Fuel not fun: Reinterpreting attenuated brain responses to reward in obesity
Kroemer NB, Small DM. Fuel not fun: Reinterpreting attenuated brain responses to reward in obesity. Physiology & Behavior 2016, 162: 37-45. PMID: 27085908, PMCID: PMC4971522, DOI: 10.1016/j.physbeh.2016.04.020.Peer-Reviewed Original ResearchConceptsFood-related stimuliBrain responsesReward-related learningReward sensitivityReward deficiencyReduced reward sensitivityPrimary food rewardReward receiptMilkshake receiptStriatal responsesReward deficitsFood rewardSubjective valueReinforcement learning frameworkRewardDopamine signalingFood anticipationDorsal striatumAnhedoniaAnticipatoryDopaminergic regionsStimuliConsummatory responsesAlternative viewLearning
2010
Evidence for an Integrated Oral Sensory Module in the Human Anterior Ventral Insula
Rudenga K, Green B, Nachtigal D, Small DM. Evidence for an Integrated Oral Sensory Module in the Human Anterior Ventral Insula. Chemical Senses 2010, 35: 693-703. PMID: 20595201, PMCID: PMC2943409, DOI: 10.1093/chemse/bjq068.Peer-Reviewed Original ResearchConceptsAnterior ventral insulaVentral insulaOral stimulationTasteless control solutionFunctional magnetic resonanceVentral pallidumPhysiological significanceHarmful stimuliInsular responsesInsulaOral sensationNutritive stimulusModalitiesDifferential connectivityPresent studyStimulationMagnetic resonanceSensory modalitiesSubjectsHypothalamusStimuliStriatumPallidum
2007
Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste
Veldhuizen MG, Bender G, Constable RT, Small DM. Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste. Chemical Senses 2007, 32: 569-581. PMID: 17495173, DOI: 10.1093/chemse/bjm025.Peer-Reviewed Original Research
2002
Toward an Understanding of the Brain Substrates of Reward in Humans
Small DM. Toward an Understanding of the Brain Substrates of Reward in Humans. Neuron 2002, 33: 668-671. PMID: 11879644, DOI: 10.1016/s0896-6273(02)00620-7.Peer-Reviewed Original Research
1997
Flavor processing
Small D, Jones-Gotman M, Zatorre R, Petrides M, Evans A. Flavor processing. Neuroreport 1997, 8: 3913-3917. PMID: 9462465, DOI: 10.1097/00001756-199712220-00014.Peer-Reviewed Original ResearchConceptsCerebral blood flow changesBlood flow changesSignificant CBF decreasePositron emission tomographySecondary gustatoryCBF decreaseBasal forebrainCBF increaseOlfactory cortexFlavor processingPrimary gustatoryEmission tomographyGustatory stimuliIndependent presentationFlavor conditionFlow changesGustatoryUnpleasant stimuliIdentical stimuliOlfactorySimultaneous presentationPresentationStimuli