2012
Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies
Tang D, Fellows L, Small D, Dagher A. Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies. Physiology & Behavior 2012, 106: 317-324. PMID: 22450260, DOI: 10.1016/j.physbeh.2012.03.009.Peer-Reviewed Original ResearchConceptsSmoking cuesOrbital frontal cortexNeutral cuesFood cuesVisual foodBlood oxygen level-dependent (BOLD) responseBrain regionsSimilar brain regionsBilateral orbital frontal cortexActivation likelihood estimationFrontal cortexFunctional MRI studyLevel-dependent responsesBrain imaging studiesNeuro-imaging studiesDrug cuesImaging studiesInsula activationSubjective cravingConditioned cuesIncentive salienceBrain responsesBilateral insulaBrain networksLeft amygdala
2010
Genetically Determined Differences in Brain Response to a Primary Food Reward
Felsted JA, Ren X, Chouinard-Decorte F, Small DM. Genetically Determined Differences in Brain Response to a Primary Food Reward. Journal Of Neuroscience 2010, 30: 2428-2432. PMID: 20164326, PMCID: PMC2831082, DOI: 10.1523/jneurosci.5483-09.2010.Peer-Reviewed Original ResearchConceptsBrain responsesPrimary food rewardFunctional magnetic resonanceTaqIA A1 alleleOrbital frontal cortexReward driveIndividual differencesNeural responsesFuture weight gainFood rewardPalatable foodNeuroimaging techniquesPerceptual responsesBiological underpinningsIndividual factorsFrontal cortexImpulsivityDiminished dopamineSimilar ratingsFood reinforcementRewardSpecific associationNeurophysiologyMilkshakeBody mass index