2021
Dietary lipids as regulators of reward processes: multimodal integration matters
Berland C, Small DM, Luquet S, Gangarossa G. Dietary lipids as regulators of reward processes: multimodal integration matters. Trends In Endocrinology And Metabolism 2021, 32: 693-705. PMID: 34148784, DOI: 10.1016/j.tem.2021.05.008.Peer-Reviewed Original ResearchConceptsDietary lipidsFunctional modulatorsModern food environmentLipid sensingPalatable dietObesity pandemicDopamine transmissionDA circuitsFeeding behaviorBody homeostasisDA signalingReward circuitRecent findingsDA systemEnergy-related signalsGenetic conditionsFood environmentFood overconsumptionNeural substratesLipidsRecent reportsSignalingRegulatorHomeostasisReward processes
2017
DRD2: Bridging the Genome and Ingestive Behavior
Sun X, Luquet S, Small DM. DRD2: Bridging the Genome and Ingestive Behavior. Trends In Cognitive Sciences 2017, 21: 372-384. PMID: 28372879, PMCID: PMC5745142, DOI: 10.1016/j.tics.2017.03.004.Peer-Reviewed Original ResearchConceptsGenetic variantsCommon gene variantsMetabolic dysfunctionNeurocognitive impairmentAppetitive functionsDA signalingCognitive declinePolygenic obesityBrain structures× environment interactionGene variantsConfer riskIngestive behaviorGene × environment interactionsNeurotransmitter dopamineObesityCognitive changesDopamineMetabolic signalsEnvironment interactionPivotal roleRiskSignalingFeedingDysfunction