2022
Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records
Thompson EJ, Williams DM, Walker AJ, Mitchell RE, Niedzwiedz CL, Yang TC, Huggins CF, Kwong ASF, Silverwood RJ, Di Gessa G, Bowyer RCE, Northstone K, Hou B, Green MJ, Dodgeon B, Doores KJ, Duncan EL, Williams FMK, Steptoe A, Porteous D, McEachan R, Tomlinson L, Goldacre B, Patalay P, Ploubidis G, Katikireddi S, Tilling K, Rentsch C, Timpson N, Chaturvedi N, Steves C. Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records. Nature Communications 2022, 13: 3528. PMID: 35764621, PMCID: PMC9240035, DOI: 10.1038/s41467-022-30836-0.Peer-Reviewed Original ResearchConceptsLong COVIDRisk factorsCardio-metabolic parametersOverweight/obesityElectronic healthcare recordsCOVID-19Community-based individualsSelf-reported COVID-19Electronic health recordsLongitudinal study sampleProlonged symptomsCOVID-19 casesFemale sexDiagnostic codesWhite ethnicityUK longitudinal studyMental healthHealth recordsStudy sampleEHR dataLongitudinal studySymptomsHealthcare recordsSpring 2021Burden
2020
Factors associated with COVID-19-related death using OpenSAFELY
Williamson EJ, Walker AJ, Bhaskaran K, Bacon S, Bates C, Morton CE, Curtis HJ, Mehrkar A, Evans D, Inglesby P, Cockburn J, McDonald HI, MacKenna B, Tomlinson L, Douglas IJ, Rentsch CT, Mathur R, Wong AYS, Grieve R, Harrison D, Forbes H, Schultze A, Croker R, Parry J, Hester F, Harper S, Perera R, Evans SJW, Smeeth L, Goldacre B. Factors associated with COVID-19-related death using OpenSAFELY. Nature 2020, 584: 430-436. PMID: 32640463, PMCID: PMC7611074, DOI: 10.1038/s41586-020-2521-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAge FactorsAgedAged, 80 and overAgingAsian PeopleAsthmaBetacoronavirusBlack PeopleCohort StudiesCoronavirus InfectionsCOVID-19Diabetes MellitusFemaleHumansHypertensionMaleMiddle AgedPandemicsPneumonia, ViralProportional Hazards ModelsRisk AssessmentSARS-CoV-2Sex CharacteristicsSmokingState MedicineYoung AdultConceptsCOVID-19-related deathsPrimary care electronic health recordsPrimary care recordsLarge cohort studyCoronavirus disease 2019Electronic health recordsSevere asthmaCohort studyClinical factorsSouth Asian peopleSevere outcomesDisease 2019Medical conditionsHigh riskOpenSAFELYWhite ethnicityCare recordsNHS EnglandPatient recordsPatient dataHealth recordsDeathGreater ageAsian peopleRisk