2022
Pharmacogenomics driven decision support prototype with machine learning: A framework for improving patient care
Kidwai-Khan F, Rentsch C, Pulk R, Alcorn C, Brandt C, Justice A. Pharmacogenomics driven decision support prototype with machine learning: A framework for improving patient care. Frontiers In Big Data 2022, 5: 1059088. PMID: 36458283, PMCID: PMC9705957, DOI: 10.3389/fdata.2022.1059088.Peer-Reviewed Original ResearchK-Nearest NeighborSupport vector machinePreventable adverse eventsDecision support mechanismAdverse eventsCurrent medicationsExtreme gradient boostingPredictive modelingSoftware interfaceMachine learningVeterans AffairsData integrationF1 scoreLarge integrated healthcare systemNearest NeighborPatient's current medicationsVector machineOutpatient clinic visitsRandom forestDecision treeGradient boostingAUC scoreComplex treatment decisionsEHR dataIntegrated healthcare system
2019
Association Between Gabapentin Receipt for Any Indication and Alcohol Use Disorders Identification Test—Consumption Scores Among Clinical Subpopulations With and Without Alcohol Use Disorder
Rentsch CT, Fiellin DA, Bryant KJ, Justice AC, Tate JP. Association Between Gabapentin Receipt for Any Indication and Alcohol Use Disorders Identification Test—Consumption Scores Among Clinical Subpopulations With and Without Alcohol Use Disorder. Alcohol Clinical And Experimental Research 2019, 43: 522-530. PMID: 30620410, PMCID: PMC6397056, DOI: 10.1111/acer.13953.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol Use Disorders Identification Test-Consumption scoresAUDIT-C scoresAlcohol consumptionUnexposed patientsClinical trialsUse disordersBaseline levelsVeterans Aging Cohort StudyDoses of gabapentinAging Cohort StudyImpact of gabapentinSubstance use treatmentDifferences linear regression modelGabapentin doseCohort studyCurrent medicationsBaseline auditMultivariable differenceClinical indicationsAUD historyPatientsGabapentinClinical subpopulationsConsecutive days