2018
Treating Sleep-Related Breathing Disorders
Won C, Mohsenin V, Kryger M. Treating Sleep-Related Breathing Disorders. 2018, 105-123. DOI: 10.1007/978-1-4939-8607-1_9.Peer-Reviewed Original ResearchPositive airway pressure therapySignificant symptomatic benefitAirway pressure therapySleep-disordered breathingMental health outcomesNeuropsychomotor functionsPAP therapyMainstay treatmentSymptomatic benefitPAP adherenceBreathing disordersPressure therapySide effectsHealth outcomesPatientsTherapyEffective alternativeAdherenceRobust evidenceTolerabilityBreathingSleep
2017
Impact of Sleep Breathing Disorders in Obese Critically Ill Patients
Al-Halawani M, Won C. Impact of Sleep Breathing Disorders in Obese Critically Ill Patients. 2017, 77-85. DOI: 10.1007/978-3-319-49253-7_8.Peer-Reviewed Original ResearchSleep breathing disordersBreathing disordersObesity hypoventilation syndromeObstructive sleep apneaSleep-disordered breathingIntensive care unitObese patientsHypoventilation syndromeIll patientsCare unitSleep apneaIll populationMajor causeObesePatientsDisordersRiskSerious riskApneaICUMorbidityComplicationsSyndromeMortalityBreathing
2016
The use of positive airway pressure therapy for treatment of resistant hypertension
Won C, Guilleminault C. The use of positive airway pressure therapy for treatment of resistant hypertension. Expert Review Of Cardiovascular Therapy 2016, 14: 505-511. PMID: 26671301, DOI: 10.1586/14779072.2016.1132626.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPositive airway pressure therapyObstructive sleep apneaAirway pressure therapyBlood pressure controlResistant hypertensionPressure therapyPressure controlSubgroup of patientsHigh-risk populationBlood pressureSleep apneaRisk factorsPathological mechanismsHypertensionNovel targetPatientsTherapyPotential mechanismsApneaMedicationsBreathingSleepTrials
2015
Gender differences in sleep disordered breathing: implications for therapy
Won C, Guilleminault C. Gender differences in sleep disordered breathing: implications for therapy. Expert Review Of Respiratory Medicine 2015, 9: 221-231. PMID: 25739831, DOI: 10.1586/17476348.2015.1019478.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep-disordered breathingSeverity of OSAUpper airway functionGender-related differencesAirway functionEndothelial dysfunctionLung functionComorbid conditionsSleep apneaTreatment optionsRespiratory stabilityImproved outcomesGender differencesGreater riskAdverse effectsWomenLimited dataAge increasesBreathingFemale presentationsHypertensionApneaAirwayPregnancy