2013
Point-of-Care Focused Cardiac Ultrasound for Prediction of Pulmonary Embolism Adverse Outcomes
Taylor RA, Davis J, Liu R, Gupta V, Dziura J, Moore CL. Point-of-Care Focused Cardiac Ultrasound for Prediction of Pulmonary Embolism Adverse Outcomes. Journal Of Emergency Medicine 2013, 45: 392-399. PMID: 23827166, DOI: 10.1016/j.jemermed.2013.04.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overEchocardiographyEmergency Service, HospitalFemaleHemorrhageHospital MortalityHumansMaleMiddle AgedPoint-of-Care SystemsPredictive Value of TestsPrognosisPulmonary EmbolismRecurrenceRespiratory InsufficiencyRetrospective StudiesRisk FactorsShockVenous ThromboembolismVentricular Dysfunction, RightConceptsRight ventricular strainHospital adverse outcomesRetrospective chart reviewPulmonary embolismAdverse outcomesEmergency departmentChart reviewCardiac ultrasoundHighest positive likelihood ratioRecurrent venous thromboembolismLow negative likelihood ratioSignificant predictorsEmergency care practitionersFocused cardiac ultrasoundFOCUS examinationPositive likelihood ratioNegative likelihood ratioMajor bleedingLikelihood ratioRespiratory failureVenous thromboembolismTransthoracic echocardiographyHospital admissionIndependent predictorsVentricular strain
2010
Clinical Features From the History and Physical Examination That Predict the Presence or Absence of Pulmonary Embolism in Symptomatic Emergency Department Patients: Results of a Prospective, Multicenter Study
Courtney DM, Kline JA, Kabrhel C, Moore CL, Smithline HA, Nordenholz KE, Richman PB, Plewa MC. Clinical Features From the History and Physical Examination That Predict the Presence or Absence of Pulmonary Embolism in Symptomatic Emergency Department Patients: Results of a Prospective, Multicenter Study. Annals Of Emergency Medicine 2010, 55: 307-315.e1. PMID: 20045580, PMCID: PMC2847003, DOI: 10.1016/j.annemergmed.2009.11.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultChest PainConfidence IntervalsEmergency Service, HospitalFemaleHumansLogistic ModelsMaleMedical History TakingMiddle AgedOdds RatioPhysical ExaminationPredictive Value of TestsProspective StudiesPulmonary EmbolismRisk FactorsSex FactorsThrombophiliaTomography, X-Ray ComputedVenous ThromboembolismVenous ThrombosisConceptsPleuritic chest painDeep venous thrombosisPulmonary embolismEmergency department patientsVenous thromboembolismChest painOdds ratioDepartment patientsVenous thrombosisFamily historySymptomatic emergency department (ED) patientsUS emergency department patientsPrediction rulePossible pulmonary embolismSubsternal chest painUnilateral leg swellingVenous thromboembolism outcomesProspective cohort studyAdjusted odds ratioActive malignancyRecent surgeryCohort studyLeg swellingPrimary outcomeFemale patients
2009
Potential Impact of Adjusting the Threshold of the Quantitative D‐dimer Based on Pretest Probability of Acute Pulmonary Embolism
Kabrhel C, Courtney D, Camargo CA, Moore CL, Richman PB, Plewa MC, Nordenholtz KE, Smithline HA, Beam DM, Brown MD, Kline JA. Potential Impact of Adjusting the Threshold of the Quantitative D‐dimer Based on Pretest Probability of Acute Pulmonary Embolism. Academic Emergency Medicine 2009, 16: 325-332. PMID: 19298619, DOI: 10.1111/j.1553-2712.2009.00368.x.Peer-Reviewed Original ResearchConceptsNegative predictive valuePulmonary embolismD-dimer testingQuantitative D-dimerPretest probabilityD-dimerVenous thromboembolismQuantitative D-dimer testingPossible pulmonary embolismAcute pulmonary embolismObservational multicenter studyMajority of patientsEmergency department patientsIntermediate pretest probabilityEmergency medicine cliniciansD-dimer cutoffHigh pretest probabilityDifferent D-dimer assaysD-dimer assayEligible patientsDepartment patientsMulticenter studyMedicine cliniciansUnstructured estimatePatientsRisk of Thromboembolism Varies, Depending on Category of Immobility in Outpatients
Beam DM, Courtney DM, Kabrhel C, Moore CL, Richman PB, Kline JA. Risk of Thromboembolism Varies, Depending on Category of Immobility in Outpatients. Annals Of Emergency Medicine 2009, 54: 147-152. PMID: 19135280, DOI: 10.1016/j.annemergmed.2008.10.033.Peer-Reviewed Original ResearchConceptsVenous thromboembolismOdds ratioSymptomatic ED patientsPrevious venous thromboembolismEmergency department patientsSignificant risk factorsLongitudinal outcome studyPositive imaging resultsCause of immobilityActive malignancyLimb immobilityNeurologic paralysisRecent surgeryDepartment patientsClinical featuresED patientsRisk factorsThromboembolismLarge cohortPresence of limbsOutcome studiesUnilateral legPatientsTypes of immobilityMultivariate analysis