2023
Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients
Ash M, Dimisko L, Chalhoub R, Howard B, Cawley C, Matouk C, Pabaney A, Spiotta A, Jabbour P, Maier I, Wolfe S, T A, Kim J, Psychogios M, Mascitelli J, Starke R, Shaban A, Yoshimura S, De Leacy R, Kan P, Fragata I, Polifka A, Arthur A, Park M, Crosa R, Williamson R, Dumont T, Levitt M, Al Kasab S, Tjoumakaris S, Liman J, Saad H, Samaniego E, Fargen K, Grossberg J, Alawieh A. Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients. Journal Of NeuroInterventional Surgery 2023, 16: 1069-1075. PMID: 37875342, DOI: 10.1136/jnis-2023-020792.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageSubpopulation of patientsProcedure timePosterior circulation strokeModified Rankin ScaleTissue plasminogen activatorEndovascular thrombectomyCirculation strokePoor outcomeGroin puncture to successful recanalizationAlberta Stroke Program Early CT ScoreAssociated with worse clinical outcomesRate of symptomatic intracranial hemorrhageIV tissue plasminogen activatorSymptomatic intracranial hemorrhage rateEffects of procedure timeIV tPA treatmentAge groupsOnset-to-groin timeAssociated with higher oddsAcute ischemic strokeCT scoreIntracranial hemorrhageDelayed presentationMulticenter study
2020
Stem Cell Therapy for Stroke
Robert S, Matouk C. Stem Cell Therapy for Stroke. 2020, 331-345. DOI: 10.1007/978-3-030-56954-9_15.ChaptersTissue plasminogen activatorCell therapyIntravenous tissue plasminogen activatorSurvival of patientsPost-ischemic brainCause of disabilityDevastating neurological disorderEffectiveness of treatmentStem cell therapyMechanical thrombectomyAcute settingSafety profileFunctional outcomeBrain damageCurrent treatmentBlood flowAnimal modelsPromising treatmentNeurological disordersBrain vasculaturePreclinical trialsStrokeTherapyPreclinical researchPatients